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IDEAYA Biosciences clinical trials

Source: ClinicalTrials.gov, U.S. National Library of Medicine and the EU Clinical Trials Information System (CTIS) — current trials in our USA, UK and EU (CTIS) registers with IDEAYA Biosciences as lead sponsor. Synced 26 Sep 2026
14Current trials
7Recruiting now
14Drugs in these trials
3Trial registers
Maintained by Sreepriya Prasannan
MSc Digital Transformation of Life Sciences (Innopharma Education / Griffith College); MSc & BSc Botany HSE Spark Ignite 2026 — Top 14 finalist
Compiled from ClinicalTrials.gov and CTIS registry records · Last verified · Editorial standards
At a glance

IDEAYA Biosciences is the lead sponsor of 14 current clinical trials in our USA, UK and EU (CTIS) registers. 7 are recruiting patients now. The most common phase is Phase 1. The drugs named most often in its trials are Darovasertib, Crizotinib and Durvalumab. The most-studied condition is Uveal Melanoma.

ClinicalTrials.gov trials by status

  • Recruiting764%
  • Active, closed436%

Trials by phase

  • Phase 1545%
  • Phase 3218%
  • Phase 1/2218%
  • Phase 2/319%
  • Phase 219%
01

Clinical trials sponsored by IDEAYA Biosciences

11 on ClinicalTrials.gov
StudyPhaseStatusStartRegisters
Neoadjuvant Darovasertib in Primary Uveal Melanoma
NCT07015190 · Uveal Melanoma
Phase 3 Recruiting 2026-01 UK, USA
Study of Adjuvant Darovasertib and Crizotinib in Participants With Primary Non-metastatic Uveal Melanoma
NCT07804186 · Uveal Melanoma
Phase 3 Recruiting 2026-09 USA
Study of IDE196 in Patients With Solid Tumors Harboring GNAQ/11 Mutations or PRKC Fusions
NCT03947385 · ClinicalTrials.gov ↗ · Metastatic Uveal Melanoma, Cutaneous Melanoma, Colorectal Cancer
Phase 1/2 Recruiting 2019-06 USA
A Study to Investigate the Safety, Pharmacokinetics, and Preliminary Efficacy of IDE574 Therapy in Adult Participants With Advanced Solid Tumors
NCT07540572 · ClinicalTrials.gov ↗ · ER+, HER 2- Breast Cancer, Non-small Cell Lung Cancer (NSCLC), Castration-resistant Prostate Cancer (CRPC)
Phase 1 Recruiting 2026-03 USA
A Study of IDE849 in Patients With DLL3 Expressing Tumors Including Small Cell Lung Cancer
NCT07174583 · ClinicalTrials.gov ↗ · Small-cell Lung Cancer, Neuroendocrine Carcinomas, Solid Tumor Show to Express DLL3
Phase 1/2 Recruiting 2025-10 USA
A Study of IDE892 as Monotherapy and Combination in MTAP-deleted Advanced Solid Tumors
NCT07277413 · ClinicalTrials.gov ↗ · NSCLC Adenocarcinoma, Gastroesophageal Cancer (GC), Gastric Adenocarcinoma
Drug: IDE397
Phase 1 Recruiting 2026-03 USA
A Study of IDE034 in Adult Participants With Locally Advanced/Metastatic Solid Tumors Types
NCT07503808 · ClinicalTrials.gov ↗ · Esophageal Squamous Cell Carcinoma, High Grade Serous Ovarian Cancer, Head and Neck Squamous Cell Carcinoma
Phase 1 Recruiting 2026-02 USA
IDE196 (Darovasertib) in Combination With Crizotinib as First-line Therapy in Metastatic Uveal Melanoma
NCT05987332 · Metastatic Uveal Melanoma
Phase 2/3 Active, closed 2023-10 UK, USA
(Neo)Adjuvant IDE196 (Darovasertib) in Patients With Localized Ocular Melanoma
NCT05907954 · Uveal Melanoma
Phase 2 Active, closed 2023-07 USA
Study of IDE397 in Participants With Solid Tumors Harboring MTAP Deletion
NCT04794699 · ClinicalTrials.gov ↗ · Solid Tumor
Phase 1 Active, closed 2021-04 USA
A Study of PARG Inhibitor IDE161 in Participants With Advanced Solid Tumors
NCT05787587 · ClinicalTrials.gov ↗ · Advanced or Metastatic Solid Tumors, Breast Cancer, Ovarian Cancer
Phase 1 Active, closed 2023-04 USA

Registers list studies that are recruiting, about to open, active but closed to enrolment, or enrolling by invitation. The UK and USA registers cover industry-sponsored studies only. Titles and statuses are copied from the registry as published.

02

IDEAYA Biosciences in the EU trials register (CTIS)

3 trials

Authorised or ongoing trials in the EU Clinical Trials Information System with IDEAYA Biosciences as sponsor. Some are the same study as a ClinicalTrials.gov record above; the two registries share no common ID. Trials with a site in Ireland are listed first.

StudyPhaseStatusCountries
A study of IDE892 as monotherapy and combination in MTAP-deleted Advanced Solid Tumors
2025-524715-37-00 · Diagnosis
Phase 1 Authorised Spain, France
An Open-Label Study of IDE034 in Adult Participants with Locally Advanced/Metastatic Solid Tumors
2026-526299-21-00 · Male Urogenital Diseases
Phase 1 Authorised Spain
A Multicenter Study Evaluating the Safety, Efficacy, and Pharmacokinetics of IDE849 in Patients with DLL3 Expressing Tumors Including Small Cell Lung Cancer
2025-523438-24-00 · CTIS ↗ · Neoplasms
Phase 1 Authorised France, Spain
03

Drugs in IDEAYA Biosciences trials

14 compounds

Drugs and biologicals named as interventions in these trials, with the number of this sponsor's trials that name each one. Placebos and generic comparators are excluded.

04

Conditions in IDEAYA Biosciences trials

24 conditions
Uveal Melanoma3Metastatic Uveal Melanoma2Colorectal Cancer2Cutaneous Melanoma1Other Solid Tumors1ER+, HER 2- Breast Cancer1Non-small Cell Lung Cancer (NSCLC)1Castration-resistant Prostate Cancer (CRPC)1Microsatellite Stable (MSS) Colorectal Carcinoma1Solid Tumor1Small-cell Lung Cancer1Neuroendocrine Carcinomas1Solid Tumor Show to Express DLL31NSCLC Adenocarcinoma1Gastroesophageal Cancer (GC)1Gastric Adenocarcinoma1Adenocarcinoma of Esophagus1Advanced or Metastatic Solid Tumors1Breast Cancer1Ovarian Cancer1Prostate Cancer1Esophageal Squamous Cell Carcinoma1High Grade Serous Ovarian Cancer1Head and Neck Squamous Cell Carcinoma1
05

By trial register

RegisterTrialsRecruiting
Clinical trials in USA117
Clinical trials in UK21
EU register (CTIS)3—

A trial with sites in more than one country appears in each of those registers.

06

Other sponsors in Uveal Melanoma

SponsorTrials
Aura Biosciences1
iOnctura1

Sponsors with the most current trials registered for this condition.

07

Questions about IDEAYA Biosciences trials

How many clinical trials does IDEAYA Biosciences sponsor?

IDEAYA Biosciences is the lead sponsor of 11 current trials on ClinicalTrials.gov in our USA and UK registers, and 3 authorised or ongoing trials in the EU register (CTIS), as of the registry sync on 26 September 2026. Completed and withdrawn studies are not counted.

Are IDEAYA Biosciences trials recruiting?

Yes. 7 of its 11 ClinicalTrials.gov trials are recruiting. Eligibility and site contacts are on each trial's record. Only the study team can confirm whether a patient is eligible.

Which drugs is IDEAYA Biosciences testing?

Its current trials name 14 drugs and biologicals as interventions. The most frequent are Darovasertib (5), Crizotinib (3), Durvalumab (2), IDE397 (2) and Pembrolizumab (2). The number in brackets is how many of its trials name each drug.

Where does this information come from?

Every trial, status, phase and condition on this page is copied from public ClinicalTrials.gov and EU CTIS records by a daily sync, grouped by the sponsor name each registry records. It says nothing about the organisation beyond its registered trials, and it is not medical advice.

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How this page is built

Everything on this page is copied from public registry records — it is not written from memory, and nothing here describes the organisation beyond its registered trials. Each trial links to its own record so you can check it yourself.

This page is built automatically: a daily sync job reads the registry records behind our trial registers and groups every current trial by its lead sponsor name, ignoring legal-form suffixes such as Inc. or Ltd. A small, hand-checked list joins the same organisation's different registry names (for example its EU legal entity). There is no AI drafting and no per-sponsor editorial pass. The “last verified” date above is the timestamp of that sync, not a review date. Our general editorial approach is described in our editorial standards and corrections policy. The the registries data on this page was last retrieved on 26 Sep 2026.

Please verify before you rely on this. This page is general information for life-science and pharmaceutical professionals. It is not medical advice, and it has not been reviewed by a clinician — our editorial team holds life-science qualifications, not clinical ones. It is not exhaustive and may not reflect the most recent label change. Always check the official prescribing information (US Prescribing Information or EU SmPC) and speak to your doctor or pharmacist before acting on anything here. Drugs in the same class are not automatically interchangeable, and approvals, brand names and indications differ between the US, the EU/Ireland (EMA/HPRA) and other regions. Spotted an error? Tell us — we correct promptly and log it.