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CRISPR Therapeutics clinical trials

Source: ClinicalTrials.gov, U.S. National Library of Medicine — current trials in our USA and UK registers with CRISPR Therapeutics as lead sponsor. Synced 26 Sep 2026
6Current trials
5Recruiting now
1Drug in these trials
2Trial registers
Maintained by Sreepriya Prasannan
MSc Digital Transformation of Life Sciences (Innopharma Education / Griffith College); MSc & BSc Botany HSE Spark Ignite 2026 — Top 14 finalist
Compiled from ClinicalTrials.gov and CTIS registry records · Last verified · Editorial standards
At a glance

CRISPR Therapeutics is the lead sponsor of 6 current clinical trials in our USA and UK registers. 5 are recruiting patients now. The most common phase is Phase 1/2. The drugs named most often in its trials are CTX112. The most-studied condition is Cardiovascular.

ClinicalTrials.gov trials by status

  • Recruiting583%
  • By invitation117%

Trials by phase

  • Phase 1/2350%
  • Phase 1233%
  • Observational117%
01

Clinical trials sponsored by CRISPR Therapeutics

6 on ClinicalTrials.gov
StudyPhaseStatusStartRegisters
A Safety and Efficacy Study Evaluating CTX112 in Adult Subjects With Refractory Autoimmune Disease
NCT06925542 · SLE (Systemic Lupus), Lupus Erythematosus, Systemic, Lupus Nephritis
Drug: CTX112
Phase 1 Recruiting 2025-03 USA
A Safety and Tolerability Trial Evaluating CTX310 in Participants With Refractory Dyslipidemias
NCT07491172 · ClinicalTrials.gov ↗ · Cardiovascular, Metabolic Disease, Dyslipidemias
Phase 1 Recruiting 2024-06 UK, USA
A Safety and Efficacy Study Evaluating CTX112 in Subjects With Relapsed or Refractory B-Cell Malignancies
NCT05643742 · ClinicalTrials.gov ↗ · B-cell Lymphoma, Non-Hodgkin Lymphoma, B-cell Malignancy
Drug: CTX112
Phase 1/2 Recruiting 2023-03 USA
A Trial Evaluating Safety, Tolerability and Efficacy of CTX340 in Participants With Hypertension
NCT07758634 · ClinicalTrials.gov ↗ · Hypertension
Phase 1/2 Recruiting 2026-08 USA
Safety and Preliminary Efficacy of CTX112 in Adult Participants With Relapsed/Refractory Hematologic Autoimmune Disease
NCT07549698 · ClinicalTrials.gov ↗ · Warm Autoimmune Hemolytic Anemia (WAIHA), ITP - Immune Thrombocytopenia, Warm Autoimmune Hemolytic Anemia
Drug: CTX112
Phase 1/2 Recruiting 2026-07 USA
A Long-term Follow-up Study of Subjects Who Received CRISPR CAR T Cellular Therapies
NCT06208878 · Hematologic Malignancy, Solid Malignancy
Observational By invitation 2023-11 USA

Registers list studies that are recruiting, about to open, active but closed to enrolment, or enrolling by invitation. The UK and USA registers cover industry-sponsored studies only. Titles and statuses are copied from the registry as published.

02

Drugs in CRISPR Therapeutics trials

1 compound

Drugs and biologicals named as interventions in these trials, with the number of this sponsor's trials that name each one. Placebos and generic comparators are excluded.

03

Conditions in CRISPR Therapeutics trials

19 conditions
Cardiovascular1Metabolic Disease1Dyslipidemias1Lipid Disorder1SLE (Systemic Lupus)1Lupus Erythematosus, Systemic1Lupus Nephritis1Systemic Sclerosis1Hematologic Malignancy1Solid Malignancy1B-cell Lymphoma1Non-Hodgkin Lymphoma1B-cell Malignancy1Chronic Lymphocytic Leukemia (CLL)/Small Lymphocytic Lymphoma (SLL)1Hypertension1Warm Autoimmune Hemolytic Anemia (WAIHA)1ITP - Immune Thrombocytopenia1Warm Autoimmune Hemolytic Anemia1Immune Thrombocytopenic Purpura1
04

By trial register

RegisterTrialsRecruiting
Clinical trials in USA65
Clinical trials in UK11

A trial with sites in more than one country appears in each of those registers.

05

Questions about CRISPR Therapeutics trials

How many clinical trials does CRISPR Therapeutics sponsor?

CRISPR Therapeutics is the lead sponsor of 6 current trials on ClinicalTrials.gov in our USA and UK registers, as of the registry sync on 26 September 2026. Completed and withdrawn studies are not counted.

Are CRISPR Therapeutics trials recruiting?

Yes. 5 of its 6 ClinicalTrials.gov trials are recruiting. Eligibility and site contacts are on each trial's record. Only the study team can confirm whether a patient is eligible.

Which drugs is CRISPR Therapeutics testing?

Its current trials name 1 drug or biological as interventions. The most frequent are CTX112 (3). The number in brackets is how many of its trials name each drug.

Where does this information come from?

Every trial, status, phase and condition on this page is copied from public ClinicalTrials.gov and EU CTIS records by a daily sync, grouped by the sponsor name each registry records. It says nothing about the organisation beyond its registered trials, and it is not medical advice.

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How this page is built

Everything on this page is copied from public registry records — it is not written from memory, and nothing here describes the organisation beyond its registered trials. Each trial links to its own record so you can check it yourself.

This page is built automatically: a daily sync job reads the registry records behind our trial registers and groups every current trial by its lead sponsor name, ignoring legal-form suffixes such as Inc. or Ltd. A small, hand-checked list joins the same organisation's different registry names (for example its EU legal entity). There is no AI drafting and no per-sponsor editorial pass. The “last verified” date above is the timestamp of that sync, not a review date. Our general editorial approach is described in our editorial standards and corrections policy. The the registries data on this page was last retrieved on 26 Sep 2026.

Please verify before you rely on this. This page is general information for life-science and pharmaceutical professionals. It is not medical advice, and it has not been reviewed by a clinician — our editorial team holds life-science qualifications, not clinical ones. It is not exhaustive and may not reflect the most recent label change. Always check the official prescribing information (US Prescribing Information or EU SmPC) and speak to your doctor or pharmacist before acting on anything here. Drugs in the same class are not automatically interchangeable, and approvals, brand names and indications differ between the US, the EU/Ireland (EMA/HPRA) and other regions. Spotted an error? Tell us — we correct promptly and log it.