Plixorafenib clinical trials
Plixorafenib is named as an intervention in 2 current clinical trials in our Australia, UK, USA, Germany, France, Spain, Italy, Netherlands, Sweden, Norway, Canada and South Korea registers. 1 is recruiting patients now. The most common phase is Phase 2. The sponsor with the most trials is Fore Biotherapeutics (1). The most-studied condition is Cancer Harboring BRAF Alterations.
Patient leaflets for Plixorafenib
The package leaflet is the official guide for patients that comes with every medicine. These links go to the regulators that publish it.
- UKUnited Kingdom: Search MHRA ProductsPatient information leaflets and SmPCs for UK-licensed products.
- USUnited States: Search DailyMedFDA-approved labels, including patient and medication guides.
Leaflets differ between brands and countries; always read the one that comes with your own medicine. This is regulatory information, not medical advice.
Trials by status
Trials by phase
Clinical trials of Plixorafenib
2 trials| Study | Phase | Status | Lead sponsor | Registers |
|---|---|---|---|---|
|
A Study to Assess the Efficacy and Safety of FORE8394 in Participants With Cancer Harboring BRAF Alterations
NCT05503797 · Cancer Harboring BRAF Alterations, HGG, LGG
|
Phase 2 | Recruiting | Fore Biotherapeutics | UK, USA, Germany, France, Spain, Italy, Netherlands, Sweden, Norway, Canada, South Korea, Australia |
|
Biomarker-guided RAdiation-deferring Treatment in Younger GBM Patients - Pilot Study
NCT07908147 · ClinicalTrials.gov ↗ · IDH Wildtype Glioblastoma, Glioblastoma (GBM)
|
Early Phase 1 | Not yet open | Olivia Newton-John Cancer Research Institute | Australia |
Registers list studies that are recruiting, about to open, active but closed to enrolment, or enrolling by invitation. The UK and USA registers cover industry-sponsored studies only. Trial titles and statuses are copied from the registry as published.
Conditions studied with Plixorafenib
6 conditionsSponsors
lead sponsor per trial| Lead sponsor | Trials |
|---|---|
| Fore Biotherapeutics | 1 |
| Olivia Newton-John Cancer Research Institute | 1 |
By country register
A trial with sites in more than one country appears in each of those registers.
Related compounds
Questions about Plixorafenib trials
How many clinical trials are testing Plixorafenib?
2 current trials in our Australia, UK, USA, Germany, France, Spain, Italy, Netherlands, Sweden, Norway, Canada and South Korea registers name Plixorafenib (also registered as FORE8394) as a drug or biological intervention, as of the registry sync on 2 November 2026. Completed and withdrawn studies are not counted.
Are Plixorafenib trials recruiting patients?
Yes. 1 of the 2 trials is recruiting: 1 with sites in Australia, 1 with sites in UK, 1 with sites in USA, 1 with sites in Germany, 1 with sites in France, 1 with sites in Spain, 1 with sites in Italy, 1 with sites in Netherlands, 1 with sites in Sweden, 1 with sites in Norway, 1 with sites in Canada and 1 with sites in South Korea. Eligibility and site contacts are on each trial's record. Only the study team can confirm whether a patient is eligible.
Who sponsors Plixorafenib clinical trials?
Fore Biotherapeutics (1) and Olivia Newton-John Cancer Research Institute (1). The number in brackets is how many trials each organisation leads.
Where does this information come from?
Every trial, status, phase and sponsor on this page is copied from public ClinicalTrials.gov records by a daily sync. Nothing here describes how Plixorafenib works or whether it is effective, and it is not medical advice.
How this page is built
Everything on this page is copied from public ClinicalTrials.gov registry records — it is not written from memory, and nothing here describes how Plixorafenib works or whether it is effective. Each trial links to its own record so you can check it yourself.
- ClinicalTrials.gov (U.S. National Library of Medicine) ↗ Trial IDs, titles, intervention names and synonyms, phase, overall status, lead sponsor and conditions for every trial on this page
This page is built automatically: a daily sync job reads the registry records behind our country trial registers, collects every trial that lists Plixorafenib (or a registered synonym) as a drug or biological intervention, and tabulates the registry fields directly. Placebos and generic comparators are excluded. There is no AI drafting and no per-compound editorial pass, and the page has not been clinically reviewed. The “last verified” date above is the timestamp of that sync, not a review date. Our general editorial approach is described in our editorial standards and corrections policy. The ClinicalTrials.gov data on this page was last retrieved on 2 Nov 2026. How every register is built: methodology · fixes we have made: corrections log.