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Compound · clinical trials

Ozone clinical trials

Also listed in trial records as O3, Ozone therapy, O3/O2 gas mixture, PubChem CID 24823
Source: ClinicalTrials.gov, U.S. National Library of Medicine — the 4 trials in our Spain and Egypt registers that name Ozone as an intervention. Synced 26 Sep 2026
4Current trials
4Recruiting now
2Lead sponsors
2Country registers
Maintained by Sreepriya Prasannan
MSc Digital Transformation of Life Sciences (Innopharma Education / Griffith College); MSc & BSc Botany HSE Spark Ignite 2026 โ€” Top 14 finalist
Compiled from ClinicalTrials.gov registry records ยท Last verified ยท Editorial standards
At a glance

Ozone is named as an intervention in 4 current clinical trials in our Spain and Egypt registers. 4 are recruiting patients now. The most common phase is Phase 2/3. The sponsor with the most trials is Bernardino Clavo, MD, PhD (3). The most-studied condition is Chemotherapy Induced Peripheral Neuropathy (CIPN).

Trials by status

  • Recruiting4100%

Trials by phase

  • Phase 2/3375%
  • Not applicable125%
01

Clinical trials of Ozone

4 trials
StudyPhaseStatusLead sponsorRegisters
Ozone Therapy in Chemotherapy-induced Peripheral Neuropathy: RCT (O3NPIQ)
NCT04299893 · ClinicalTrials.gov ↗ · Chemotherapy-induced Peripheral Neuropathy, Pain, Neuropathic, Pain Syndrome
Phase 2/3 Recruiting Bernardino Clavo, MD, PhD Spain
Ozone Treatment in Paresthesia (Numbness, Tingling) Secondary to Chemotherapy-induced Peripheral Neuropathy
NCT06706544 · ClinicalTrials.gov ↗ · Chemotherapy Induced Peripheral Neuropathy (CIPN), Paresthesia, Numbness
Phase 2/3 Recruiting Bernardino Clavo, MD, PhD Spain
Gut Microbiome Profiles in Patients With Chemotherapy-induced Neuropathy in the RCT OzoParQT (NCT06706544).
NCT06799351 · ClinicalTrials.gov ↗ · Chemotherapy Induced Peripheral Neuropathy (CIPN), Paresthesia, Numbness
Phase 2/3 Recruiting Bernardino Clavo, MD, PhD Spain
Dexmedetomidine, Ozone and Dexamethasone Local Injection in Carpal Tunnel Syndrome for Pain Relief
NCT06133712 · ClinicalTrials.gov ↗ · Carpal Tunnel, Dexmedetomidine, Ozone
Not applicable Recruiting Tanta University Egypt

Registers list studies that are recruiting, about to open, active but closed to enrolment, or enrolling by invitation. The UK and USA registers cover industry-sponsored studies only. Trial titles and statuses are copied from the registry as published.

02

Conditions studied with Ozone

11 conditions
Chemotherapy Induced Peripheral Neuropathy (CIPN)2Paresthesia2Numbness2Tingling2Chemotherapy-induced Peripheral Neuropathy1Pain, Neuropathic1Pain Syndrome1Carpal Tunnel1Dexmedetomidine1Ozone1Dexamethasone1
03

Sponsors

lead sponsor per trial
Lead sponsorTrials
Bernardino Clavo, MD, PhD3
Tanta University1
04

By country register

RegisterTrialsRecruiting
Clinical trials in Spain33
Clinical trials in Egypt11

A trial with sites in more than one country appears in each of those registers.

05

Related compounds

06

Questions about Ozone trials

How many clinical trials are testing Ozone?

4 current trials in our Spain and Egypt registers name Ozone (also registered as O3) as a drug or biological intervention, as of the registry sync on 26 September 2026. Completed and withdrawn studies are not counted.

Are Ozone trials recruiting patients?

Yes. 4 of the 4 trials are recruiting: 3 with sites in Spain and 1 with sites in Egypt. Eligibility and site contacts are on each trial's record. Only the study team can confirm whether a patient is eligible.

Who sponsors Ozone clinical trials?

Bernardino Clavo, MD, PhD (3) and Tanta University (1). The number in brackets is how many trials each organisation leads.

Where does this information come from?

Every trial, status, phase and sponsor on this page is copied from public ClinicalTrials.gov records by a daily sync. Nothing here describes how Ozone works or whether it is effective, and it is not medical advice.

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How this page is built

Everything on this page is copied from public ClinicalTrials.gov registry records โ€” it is not written from memory, and nothing here describes how Ozone works or whether it is effective. Each trial links to its own record so you can check it yourself.

This page is built automatically: a daily sync job reads the registry records behind our country trial registers, collects every trial that lists Ozone (or a registered synonym) as a drug or biological intervention, and tabulates the registry fields directly. Placebos and generic comparators are excluded. There is no AI drafting and no per-compound editorial pass, and the page has not been clinically reviewed. The “last verified” date above is the timestamp of that sync, not a review date. Our general editorial approach is described in our editorial standards and corrections policy. The ClinicalTrials.gov data on this page was last retrieved on 26 Sep 2026.

Please verify before you rely on this. This page is general information for life-science and pharmaceutical professionals. It is not medical advice, and it has not been reviewed by a clinician โ€” our editorial team holds life-science qualifications, not clinical ones. It is not exhaustive and may not reflect the most recent label change. Always check the official prescribing information (US Prescribing Information or EU SmPC) and speak to your doctor or pharmacist before acting on anything here. Drugs in the same class are not automatically interchangeable, and approvals, brand names and indications differ between the US, the EU/Ireland (EMA/HPRA) and other regions. Spotted an error? Tell us โ€” we correct promptly and log it.