Ireland
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Priya Life Science Compound trial record
Compound · clinical trials

Methylprednisolone acetate clinical trials

Also listed in trial records as Depo-Medrone, Depo-Medron
Source: ClinicalTrials.gov, U.S. National Library of Medicine — the 2 trials in our Netherlands and Turkey registers that name Methylprednisolone acetate as an intervention. Synced 23 Oct 2026
2Current trials
1Recruiting now
2Lead sponsors
2Country registers
At a glance

Methylprednisolone acetate is named as an intervention in 2 current clinical trials in our Netherlands and Turkey registers. 1 is recruiting patients now. The most common phase is Phase 3. The sponsor with the most trials is Sint Maartenskliniek (1). The most-studied condition is Hand Osteoarthritis.

Where Methylprednisolone acetate is approved

All regulators →

Of the three regulators tracked here, the first to approve Methylprednisolone acetate was the US, on 24 Oct 1957.

USUnited States (FDA)
24 Oct 1957
Medrol
NDA011153 on Drugs@FDA
First original NDA/BLA approval
EUEuropean Union (EMA)
No centralised EU authorisation (it may be authorised nationally)
First centralised authorisation
CACanada (Health Canada)
No new-drug Notice of Compliance since 1994
First new-drug NOC

From the regulators' own registers: FDA Drugs@FDA, the EMA medicines list and Health Canada's Notice of Compliance database. Dates are the first listed approval of a product containing only this substance; combination products and nationally authorised EU medicines are not counted.

What health systems spend on Methylprednisolone acetate

All medicines →
ENNHS England
£4.0m
778,743 items dispensed, Aug 2025 to Jul 2026
+22% on the previous 12 months
Net ingredient cost, community prescriptions
USUS Medicaid
$24.8m
2,839,356 prescriptions in 2025 · Methylprednisolone, MethylPREDNISolone, Solu-medrol
-14% on 2024
Amount Medicaid reimbursed, before rebates

From NHSBSA Prescription Cost Analysis (Open Government Licence v3.0) and CMS State Drug Utilization Data. Both are gross amounts: neither system publishes its discounts or rebates per drug. Products combining several substances are not counted here.

How Methylprednisolone acetate works

All drug targets →
  • Glucocorticoid receptor agonist Agonist
    Target: NR3C1 nuclear receptor subfamily 3 group C member 1
    ✓ In ChEMBL and the Guide to Pharmacology
Diseases it has been tested for in clinical trials, by furthest phase
  • Bell's palsyPhase 3
  • COVID-19–associated multisystem inflammatory syndrome in childrenPhase 3
  • Acoustic neuromaPhase 3
  • Acute myeloid leukemiaPhase 3
  • Acute respiratory distress syndromePhase 3
  • Ischemic strokePhase 3
  • Sudden sensorineural hearing lossPhase 3
  • COVID-19Phase 2
  • HeadachePhase 2
  • Acute graft versus host diseasePhase 2
16 diseases in all

Mechanisms and diseases from ChEMBL via the Open Targets Platform (release 26.09), ChEMBL record CHEMBL1201081, CC BY-SA 3.0. Targets checked against the IUPHAR/BPS Guide to PHARMACOLOGY (2026.3), ligand 7088, CC BY-SA 4.0. Trial phases are not approvals: approved uses are shown from the regulators' own records where we hold them.

Patient leaflets for Methylprednisolone acetate

The package leaflet is the official guide for patients that comes with every medicine. These links go to the regulators that publish it.

Leaflets differ between brands and countries; always read the one that comes with your own medicine. This is regulatory information, not medical advice.

Reference identifiers for Methylprednisolone acetate

ChEMBL
CHEMBL1201081
PubChem CID
23680530
CAS number
2375-03-3
FDA UNII
LEC9GKY20K
Wikidata
Q27282942
Wikipedia
Methylprednisolone succinate

Codes that identify this medicine in other databases, from Wikidata (CC0), matched by its ChEMBL ID. The ATC code is the WHO classification of what the medicine is used for.

Trials by status

  • Recruiting150%
  • Not yet open150%

Trials by phase

  • Phase 3150%
  • Not applicable150%
01

Clinical trials of Methylprednisolone acetate

2 trials
StudyPhaseStatusLead sponsorRegisters
The Efficacy and Safety of Intramuscular Methylprednisolone in Patients With Hand OsteoArthritis
NCT07371572 · ClinicalTrials.gov ↗ · Hand Osteoarthritis
Phase 3 Recruiting Sint Maartenskliniek Netherlands
Comparative Effectiveness of Ultrasound-Guided Tenoxicam and Corticosteroid Injections for Lateral Epicondylitis
NCT07883876 · ClinicalTrials.gov ↗ · Lateral Epicondylitis
Not applicable Not yet open Ankara Etlik City Hospital Turkey

Registers list studies that are recruiting, about to open, active but closed to enrolment, or enrolling by invitation. The UK and USA registers cover industry-sponsored studies only. Trial titles and statuses are copied from the registry as published.

02

Conditions studied with Methylprednisolone acetate

2 conditions
Hand Osteoarthritis1Lateral Epicondylitis1
03

Sponsors

lead sponsor per trial
Lead sponsorTrials
Sint Maartenskliniek1
Ankara Etlik City Hospital1
04

By country register

RegisterTrialsRecruiting
Clinical trials in Netherlands11
Clinical trials in Turkey10

A trial with sites in more than one country appears in each of those registers.

05

Related compounds

06

Questions about Methylprednisolone acetate trials

How many clinical trials are testing Methylprednisolone acetate?

2 current trials in our Netherlands and Turkey registers name Methylprednisolone acetate as a drug or biological intervention, as of the registry sync on 23 October 2026. Completed and withdrawn studies are not counted.

Are Methylprednisolone acetate trials recruiting patients?

Yes. 1 of the 2 trials is recruiting: 1 with sites in Netherlands. Eligibility and site contacts are on each trial's record. Only the study team can confirm whether a patient is eligible.

Who sponsors Methylprednisolone acetate clinical trials?

Sint Maartenskliniek (1) and Ankara Etlik City Hospital (1). The number in brackets is how many trials each organisation leads.

Where does this information come from?

Every trial, status, phase and sponsor on this page is copied from public ClinicalTrials.gov records by a daily sync. Nothing here describes how Methylprednisolone acetate works or whether it is effective, and it is not medical advice.

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How this page is built

Everything on this page is copied from public ClinicalTrials.gov registry records — it is not written from memory, and nothing here describes how Methylprednisolone acetate works or whether it is effective. Each trial links to its own record so you can check it yourself.

This page is built automatically: a daily sync job reads the registry records behind our country trial registers, collects every trial that lists Methylprednisolone acetate (or a registered synonym) as a drug or biological intervention, and tabulates the registry fields directly. Placebos and generic comparators are excluded. There is no AI drafting and no per-compound editorial pass, and the page has not been clinically reviewed. The “last verified” date above is the timestamp of that sync, not a review date. Our general editorial approach is described in our editorial standards and corrections policy. The ClinicalTrials.gov data on this page was last retrieved on 23 Oct 2026. How every register is built: methodology · fixes we have made: corrections log.

Please verify before you rely on this. This page is general information for life-science and pharmaceutical professionals. It is not medical advice, and it has not been reviewed by a clinician — our editorial team holds life-science qualifications, not clinical ones. It is not exhaustive and may not reflect the most recent label change. Always check the official prescribing information (US Prescribing Information or EU SmPC) and speak to your doctor or pharmacist before acting on anything here. Drugs in the same class are not automatically interchangeable, and approvals, brand names and indications differ between the US, the EU/Ireland (EMA/HPRA) and other regions. Spotted an error? Tell us — we correct promptly and log it.