Luvometinib clinical trials
Luvometinib is named as an intervention in 11 current clinical trials in our China register. 6 are recruiting patients now. The most common phase is Phase 2. The sponsor with the most trials is Shanghai Fosun Pharmaceutical Industrial Development Co. Ltd (4). The most-studied condition is Langerhans Cell Histiocytosis (LCH).
How Luvometinib works
All drug targets →- Low grade gliomaPhase 3
- Plexiform neurofibromaPhase 3
- Langerhans cell histiocytosisPhase 2
- NF2-related schwannomatosisPhase 2
- Arteriovenous malformations of the brainPhase 2
- Nerve sheath neoplasmPhase 2
- NeurofibromaPhase 2
- Neurofibromatosis type 1Phase 2
- Non-small cell lung carcinomaPhase 2
Mechanisms and diseases from ChEMBL via the Open Targets Platform (release 26.09), ChEMBL record CHEMBL6068059, CC BY-SA 3.0. Targets checked against the IUPHAR/BPS Guide to PHARMACOLOGY (2026.3.1), ligand 13495, CC BY-SA 4.0. Trial phases are not approvals: approved uses are shown from the regulators' own records where we hold them.
Patient leaflets for Luvometinib
The package leaflet is the official guide for patients that comes with every medicine. These links go to the regulators that publish it.
- UKUnited Kingdom: Search MHRA ProductsPatient information leaflets and SmPCs for UK-licensed products.
- USUnited States: Search DailyMedFDA-approved labels, including patient and medication guides.
Leaflets differ between brands and countries; always read the one that comes with your own medicine. This is regulatory information, not medical advice.
Trials by status
Trials by phase
Clinical trials of Luvometinib
11 trialsRegisters list studies that are recruiting, about to open, active but closed to enrolment, or enrolling by invitation. The UK and USA registers cover industry-sponsored studies only. Trial titles and statuses are copied from the registry as published.
Conditions studied with Luvometinib
21 conditionsAll 21 conditions
| Condition (as registered) | Trials |
|---|---|
| Langerhans Cell Histiocytosis (LCH) | 2 |
| Neurofibromatosis Type 2 | 2 |
| Vestibular Schwannoma | 2 |
| Langerhans Cell Histiocytosis | 2 |
| Non-vestibular Schwannoma | 1 |
| Meningioma | 1 |
| Low-grade Glioma | 1 |
| Pediatric Low-grade Gliomas | 1 |
| pLGG With BRAF Alteration | 1 |
| NF2-related Schwannomatosis | 1 |
| NF2 | 1 |
| Non-small Cell Lung Caner | 1 |
| KRAS-mutated | 1 |
| Metastasis | 1 |
| Previous Treamted | 1 |
| Neurofibromatosis 1 | 1 |
| Plexiform Neurofibroma | 1 |
| NF1 | 1 |
| Brain Arteriovenous Malformations | 1 |
| Nerve Sheath Tumor | 1 |
| LCH | 1 |
Sponsors
lead sponsor per trialBy country register
| Register | Trials | Recruiting |
|---|---|---|
| Clinical trials in China | 11 | 6 |
A trial with sites in more than one country appears in each of those registers.
Related compounds
Questions about Luvometinib trials
How many clinical trials are testing Luvometinib?
11 current trials in our China register name Luvometinib (also registered as FCN-159) as a drug or biological intervention, as of the registry sync on 10 November 2026. Completed and withdrawn studies are not counted.
Are Luvometinib trials recruiting patients?
Yes. 6 of the 11 trials are recruiting: 6 with sites in China. Eligibility and site contacts are on each trial's record. Only the study team can confirm whether a patient is eligible.
Who sponsors Luvometinib clinical trials?
Shanghai Fosun Pharmaceutical Industrial Development Co. Ltd (4), West China Second University Hospital (2), Beijing Tiantan Hospital (2) and Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University (1), among 6 lead sponsors in total. The number in brackets is how many trials each organisation leads.
Where does this information come from?
Every trial, status, phase and sponsor on this page is copied from public ClinicalTrials.gov records by a daily sync. Nothing here describes how Luvometinib works or whether it is effective, and it is not medical advice.
How this page is built
Everything on this page is copied from public ClinicalTrials.gov registry records — it is not written from memory, and nothing here describes how Luvometinib works or whether it is effective. Each trial links to its own record so you can check it yourself.
- ClinicalTrials.gov (U.S. National Library of Medicine) ↗ Trial IDs, titles, intervention names and synonyms, phase, overall status, lead sponsor and conditions for every trial on this page
This page is built automatically: a daily sync job reads the registry records behind our country trial registers, collects every trial that lists Luvometinib (or a registered synonym) as a drug or biological intervention, and tabulates the registry fields directly. Placebos and generic comparators are excluded. There is no AI drafting and no per-compound editorial pass, and the page has not been clinically reviewed. The “last verified” date above is the timestamp of that sync, not a review date. Our general editorial approach is described in our editorial standards and corrections policy. The ClinicalTrials.gov data on this page was last retrieved on 10 Nov 2026. How every register is built: methodology · fixes we have made: corrections log.