Calcium clinical trials
Calcium is named as an intervention in 3 current clinical trials in our Germany, Canada and Israel registers. 3 are recruiting patients now. The most common phase is Not applicable. The sponsor with the most trials is Nicolas Schlegel (1). The most-studied condition is Postoperative Hypoparathyroidism. The EU clinical trials register (CTIS) separately lists 1 authorised or ongoing trial.
Where Calcium is approved
All regulators →Of the three regulators tracked here, the first to approve Calcium was the US, on 10 Dec 1990. It is approved in 2 of the 3 regulators tracked here.
From the regulators' own registers: FDA Drugs@FDA, the EMA medicines list and Health Canada's Notice of Compliance database. Dates are the first listed approval of a product containing only this substance; combination products and nationally authorised EU medicines are not counted.
What health systems spend on Calcium
All medicines →From NHSBSA Prescription Cost Analysis (Open Government Licence v3.0) and CMS State Drug Utilization Data. Both are gross amounts: neither system publishes its discounts or rebates per drug. Products combining several substances are not counted here.
How Calcium works
All drug targets →- InfertilityPhase 3
- Breast cancerPhase 3
- HyperprolactinemiaPhase 3
- Hypertensive disorderPhase 3
- Idiopathic juvenile osteoporosisPhase 3
- Osteogenesis imperfectaPhase 3
- Polycystic ovary syndromePhase 3
- Male infertilityPhase 2/3
- Spermatogenic failurePhase 2/3
- Chronic painPhase 2
Mechanisms and diseases from ChEMBL via the Open Targets Platform (release 26.09), ChEMBL record CHEMBL1200496, CC BY-SA 3.0. The Guide to Pharmacology has no record of this medicine, so its targets rest on ChEMBL alone. Trial phases are not approvals: approved uses are shown from the regulators' own records where we hold them.
Patient leaflets for Calcium
The package leaflet is the official guide for patients that comes with every medicine. These links go to the regulators that publish it.
- IEIreland: 4 products on the HPRA listEach product record links to the HPRA, which publishes the leaflet and SmPC.
- UKUnited Kingdom: Search MHRA ProductsPatient information leaflets and SmPCs for UK-licensed products.
- USUnited States: Search DailyMedFDA-approved labels, including patient and medication guides.
Leaflets differ between brands and countries; always read the one that comes with your own medicine. This is regulatory information, not medical advice.
Trials by status
Trials by phase
Clinical trials of Calcium
3 trials| Study | Phase | Status | Lead sponsor | Registers |
|---|---|---|---|---|
|
Low Sodium Oxybate in Patients With Idiopathic Hypersomnia
NCT05837091 · ClinicalTrials.gov ↗ · Idiopathic Hypersomnia
|
Phase 4 | Recruiting | Mayo Clinic | Israel |
|
Effect of Extracellular Calcium on Carbetocin Mediated Contractility in Human Myometrium
NCT06930391 · ClinicalTrials.gov ↗ · Postpartum Hemorrhage (Primary)
|
Not applicable | Recruiting | Samuel Lunenfeld Research Institute, Mount Sinai Hospital | Canada |
|
PRESS -PAR: Early Detection and PREvention of Symptomatic postSurgical hypoPARathyroidism After Thyroid Surgery"
NCT07491601 · ClinicalTrials.gov ↗ · Postoperative Hypoparathyroidism, Postsurgical Hypoparathyroidism, Hypoparathyroidism Post-surgical
|
Not applicable | Recruiting | Nicolas Schlegel | Germany |
Registers list studies that are recruiting, about to open, active but closed to enrolment, or enrolling by invitation. The UK and USA registers cover industry-sponsored studies only. Trial titles and statuses are copied from the registry as published.
Calcium in the EU trials register (CTIS)
1 trialAuthorised or ongoing trials in the EU Clinical Trials Information System that list a product containing Calcium. Many trials are registered in both CTIS and ClinicalTrials.gov, so these are shown separately rather than added to the count above. Trials with a site in Ireland are listed first.
| Study | Phase | Status | Sponsor | Countries |
|---|---|---|---|---|
|
Evaluation of the Impact of a Strategy of Perioperative NSAID Suppression in Patients Undergoing Video-assisted Thoracic Surgery (VATS) on the Presence of Chronic Postoperative Pain (CPOP): a Randomised Clinical Trial (EVADRAINS)
2025-524917-96-00 · Not possible to specify
|
Phase 3 | Authorised | Les Hopitaux Universitaires De Strasbourg | France |
Calcium across our data
Ireland · EU · USThe same active substance in our other registers, matched by its exact name. Each entry links to the register record it comes from.
Licensed in Ireland (HPRA)
4 single-substance products containing Calcium on the HPRA medicines list.
- Calrecia 100 mmol/l, solution for infusionFresenius Medical Care Deutschland GmbH · PA1350/006/001 · Marketed
- Calcichew 500 mg chewable tabletsPCO Manufacturing Ltd. · PPA0465/156/001
- Calcium Acetate 500mg TabletsPinewood Laboratories Ltd · PA0281/063/001 · Not marketed
- Icalziss 340 mmol/L solution for infusionVantive Belgium SRL · PA25288/010/001 · Not marketed
Supply shortages
- Calcium Chloride; Dextrose; Magnesium Chloride; Sodium Chloride; Sodium Lactate Intraperitoneal Injection, SolutionUS (FDA) · Resolved · updated 3 Aug 2026
- Calcium Chloride InjectionUS (FDA) · Resolved · updated 7 Nov 2025
- OsvaRenGermany (BfArM) · Production problem · 24 Mar 2025 to 31 Mar 2027
Conditions studied with Calcium
5 conditionsSponsors
lead sponsor per trial| Lead sponsor | Trials |
|---|---|
| Nicolas Schlegel | 1 |
| Samuel Lunenfeld Research Institute, Mount Sinai Hospital | 1 |
| Mayo Clinic | 1 |
By country register
| Register | Trials | Recruiting |
|---|---|---|
| Clinical trials in Germany | 1 | 1 |
| Clinical trials in Canada | 1 | 1 |
| Clinical trials in Israel | 1 | 1 |
| EU register (CTIS) | 1 | — |
A trial with sites in more than one country appears in each of those registers. CTIS does not publish a recruiting flag; its trials may also appear in the registers above.
Related compounds
Questions about Calcium trials
How many clinical trials are testing Calcium?
3 current trials in our Germany, Canada and Israel registers name Calcium as a drug or biological intervention, as of the registry sync on 10 November 2026. Completed and withdrawn studies are not counted.
Are Calcium trials recruiting patients?
Yes. 3 of the 3 trials are recruiting: 1 with sites in Germany, 1 with sites in Canada and 1 with sites in Israel. Eligibility and site contacts are on each trial's record. Only the study team can confirm whether a patient is eligible.
Who sponsors Calcium clinical trials?
Nicolas Schlegel (1), Samuel Lunenfeld Research Institute, Mount Sinai Hospital (1) and Mayo Clinic (1). The number in brackets is how many trials each organisation leads.
Is Calcium licensed in Ireland?
Yes. The HPRA medicines list includes 4 single-substance products containing Calcium, for example Calrecia 100 mmol/l, solution for infusion (Fresenius Medical Care Deutschland GmbH). A licence does not mean a product is currently marketed or reimbursed; see each product's record.
Is there a Calcium shortage?
The registers we track list 3 entries for Calcium: US FDA: resolved; US FDA: resolved; 1 German notice. Shortages are product- and country-specific; check with a pharmacist.
Where does this information come from?
Every trial, status, phase and sponsor on this page is copied from public ClinicalTrials.gov records by a daily sync. Nothing here describes how Calcium works or whether it is effective, and it is not medical advice.
How this page is built
Everything on this page is copied from public ClinicalTrials.gov registry records — it is not written from memory, and nothing here describes how Calcium works or whether it is effective. Each trial links to its own record so you can check it yourself.
- ClinicalTrials.gov (U.S. National Library of Medicine) ↗ Trial IDs, titles, intervention names and synonyms, phase, overall status, lead sponsor and conditions for every trial on this page
This page is built automatically: a daily sync job reads the registry records behind our country trial registers, collects every trial that lists Calcium (or a registered synonym) as a drug or biological intervention, and tabulates the registry fields directly. Placebos and generic comparators are excluded. There is no AI drafting and no per-compound editorial pass, and the page has not been clinically reviewed. The “last verified” date above is the timestamp of that sync, not a review date. Our general editorial approach is described in our editorial standards and corrections policy. The ClinicalTrials.gov data on this page was last retrieved on 10 Nov 2026. How every register is built: methodology · fixes we have made: corrections log.