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Zebeta vs Lopressor

Bisoprolol  ·  Metoprolol

Both are beta blockers. Here is how Zebeta and Lopressor compare on class, mechanism, dosing, approval and supply.

At a glance

ZebetaBisoprolol
LopressorMetoprolol
Brand names
Zebeta / Cardicor
Lopressor / Toprol-XL
Drug class
Beta blocker
Beta blocker
Route
Not listed
Oral
Marketed by
Teva
Validus Pharmaceuticals
First FDA approval
31 Jul 1992
7 Aug 1978
US shortage
Not listed
Not listed

Key differences

What each one treats

ZebetaBisoprolol

An oral daily medication used to treat high blood pressure and chronic heart failure.

LopressorMetoprolol

1 IND ICATIONS AND USAGE LOPRESSOR is a beta-adrenergic blocker indicated for the treatment of: Hypertension, to lower blood pressure. Lowering blood pressure reduces the risk of fatal and non-fatal cardiovascular events, primarily strokes and myocardial infarctions. ( 1.1 ) Angina Pectoris. ( 1.2 ) Myocardial Infarction, to reduce the risk of cardiovascular mortality when used in conjunction with intravenous metoprolol therapy in patients with definite or suspected acute myocardial infarction in hemodynamically stable patients. ( 1.3 ) 1.1 Hypertension LOPRESSOR is indicated for the treatment of hypertension in adult patients, to lower blood pressure. Lowering blood pressure lowers the risk of fatal and non-fatal cardiovascular events, primarily strokes and myocardial infarctions. These benefits have been seen in controlled trials of antihypertensive drugs from a wide variety of pharma…

How each one works

ZebetaBeta blocker

An oral daily medication used to treat high blood pressure and chronic heart failure.

LopressorBeta blocker

12.1 Mechanism of Action Metoprolol is a beta 1 -selective (cardioselective) adrenergic receptor blocking agent. This preferential effect is not absolute, however, and at higher plasma concentrations, metoprolol also inhibits beta 2 -adrenoreceptors, chiefly located in the bronchial and vascular musculature. Metoprolol has no intrinsic sympathomimetic activity, and membrane-stabilizing activity is detectable only at plasma concentrations much greater than required for beta-blockade. Animal and human experiments indicate that metoprolol slows the sinus rate and decreases AV nodal conduction. The relative beta 1 -selectivity of metoprolol has been confirmed by the following: (1) In normal sub…

Related comparisons

Zebeta VS Coreg Zebeta VS Bystolic Lopressor VS Coreg Lopressor VS Bystolic

Read more

Zebeta profile Lopressor profile Beta Blockers All comparisons
This is not medical advice, and not a recommendation of one drug over the other.

Which medicine is right for a given person depends on their diagnosis, other conditions, other medicines, kidney and liver function, pregnancy, and cost or reimbursement — none of which this page knows. Two drugs in the same class are not automatically interchangeable. Never start, stop or switch a prescription medicine on the basis of a web page; that decision belongs to you and your clinician or pharmacist.

Class and summary text is written by the Priya Life Science editorial team. Label, mechanism, route, manufacturer and approval data come from the U.S. FDA via the openFDA API; shortage status from the FDA Drug Shortage Database. Approvals, indications and brand names differ between the US, EU/Ireland (EMA/HPRA) and other regions — a drug approved in one may not be approved, or may carry a different name, in another.