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Home›Companies›Autolus Therapeutics
Autolus Therapeutics logo

Autolus Therapeutics

London, United Kingdom Biotech 700 employees Founded 2014 AUTL autolus.com ↗
6 Products & services
1 Licensed medicines
6 Clinical trials
700 Employees

About Autolus Therapeutics

Autolus is a London-based clinical-stage biopharma developing next-generation programmed T-cell (CAR-T) therapies for cancer.

Sector
Biotech
Headquarters
London, United Kingdom
Founded
2014
Employees
700

Milestones

Milestones as listed on autolus.com, checked 26 Sep 2026. Details can change; the linked page is the authoritative source.

2014
Founded as a UCL spin-out by Dr Martin Pule
Also received a 30 million GBP Series A from founding investor Syncona.
Source: autolus.com
2016
Secured 40 million GBP Series B financing
Source: autolus.com
2018
IPO on Nasdaq
Raised a total of $160.4 million; also secured $80 million Series C.
Source: autolus.com
2019
Opened an office in Maryland, USA
Source: autolus.com
2021
Strategic collaboration with Blackstone
Up to $250 million to develop obe-cel in adult ALL.
Source: autolus.com
2022
Pivotal Phase 2 FELIX study met primary end point
First clean rooms handed over in Stevenage the same year.
Source: autolus.com
2024
US FDA approved AUCATZYL
Also a CAR T collaboration with BioNTech and a $350 million public offering.
Source: autolus.com
2025
MHRA conditional and EC marketing authorisations for AUCATZYL
Source: autolus.com

Leadership Team

Leadership as listed on autolus.com, checked 26 Sep 2026. Details can change; the linked page is the authoritative source.

Dr Christian Itin

Chief Executive Officer
Source: autolus.com

Rob Dolski

Chief Financial Officer
Source: autolus.com

Dr Martin Pule

Founder and Chief Scientific Officer
Source: autolus.com

Christopher Vann

Chief Operating Officer
Source: autolus.com

Miranda Neville

Chief Technology Officer
Source: autolus.com

Dr Matthias Will

Chief Development Officer
Source: autolus.com

Products & Services

Products and services as listed on autolus.com, checked 26 Sep 2026. Details can change; the linked page is the authoritative source.

All CAR T cell therapy Autoimmune (clinical) CAR T candidate T cell therapy candidates Solid tumour candidate
CAR T cell therapy

Obe-cel

Lead CAR T cell therapy, being investigated in ongoing oncology and autoimmune disease studies.

Source: autolus.com
Autoimmune (clinical)

Obe-cel in SLE

Phase 1 study of obe-cel in refractory systemic lupus erythematosus.

Source: autolus.com
CAR T candidate

AUTO1/22

Dual-targeting CD19/CD22 CAR T candidate built on obe-cel.

Source: autolus.com
T cell therapy candidates

AUTO4 and AUTO5

Programmed T cell therapies for peripheral T-cell lymphoma targeting TRBC1 and TRBC2.

Source: autolus.com
Solid tumour candidate

AUTO6NG

GD2-targeting programmed T cell therapy for neuroblastoma and other GD2-expressing solid tumours.

Source: autolus.com
CAR T candidate

AUTO8

Next-generation dual-CAR candidate for multiple myeloma targeting BCMA and CD19.

Source: autolus.com

Pipeline & Regulatory Record

What public registers list for Autolus Therapeutics: clinical trials it sponsors, FDA device clearances, Irish licences, recent approvals and supply shortages. Rebuilt daily, last on 10 Oct 2026.

6Trials as lead sponsor
3Recruiting now
0With a site in Ireland
0FDA device clearances

Clinical trials 6 in our ClinicalTrials.gov registers · 1 in the EU register

StudyPhaseStatus
Obe-cel in Adolescent [Applicable in UK Only] and Adult Severe, Refractory Systemic Lupus Erythematosus
NCT06333483 · Systemic Lupus Erythematosus
Phase 1Active, closed
A Study of CD19 Targeted CAR T Cell Therapy in Adult Patients With Relapsed or Refractory B Cell Acute Lymphoblastic Leukaemia (ALL)
NCT04404660 · Relapsed or Refractory B Cell Acute Lymphoblastic Leukemia
Phase 1/2Active, closed
Long-term Follow-up of Patients Treated With Genetically Modified Autologous T Cells
NCT03628612 · Patients Followed for up to 15 Years Following Their First Dose of AUTO CAR T Cell Therapy, Multiple Myeloma
Phase 2By invitation
Obe-cel in Severe, Refractory Systemic Lupus Erythematosus (SLE) With Active Lupus Nephritis (LN)
NCT07053800 · Lupus Nephritis
Phase 2Recruiting
Obe-cel in Refractory Progressive Forms of Multiple Sclerosis
NCT07139743 · Progressive Multiple Sclerosis
Phase 1Recruiting
A Study of CD19 Targeted CAR T Cell Therapy in Pediatric Patients With Relapsed or Refractory B Cell Acute Lymphoblastic Leukemia (B ALL) and Aggressive Mature B-cell Non-Hodgkin Lymphoma (B NHL)
NCT06173518 · Relapsed or Refractory B Cell Acute Lymphoblastic Leukemia, Relapsed or Refractory B Cell Non-Hodgkin Lymphoma
Phase 1Recruiting

All trials by sponsor name 1 registry name

Drugs in these trials 2 compounds

EU trials register (CTIS) 1 authorised or ongoing

Group (Autolus Therapeutics): founded 2014, website autolus.com. Wikidata Q56583577. From Wikidata (CC0), matched by the group's Legal Entity Identifier.

How this is matched: register records are linked to this page by the organisation name they carry, here Autolus Limited; Autolus GmbH. Spot a wrong match? Tell us.

Financials & Irish Entities

From the annual reports Autolus Therapeutics plc files with the US Securities and Exchange Commission (10-K, US GAAP), in USD as reported. Latest financial year: to Dec 2025.

$75.4mRevenue
$118mR&D expense
156.1%R&D as % of revenue
−$288mNet income (-381.4% margin)
Revenue and R&D expense, USD m$0.0m$50m$100m$150mSep 2018Dec 2019Dec 2023Dec 2024Dec 2025Sep 2018: $1.4m (Revenue)Dec 2019: $2.9m (Revenue)Dec 2023: $1.7m (Revenue)Dec 2024: $10m (Revenue)Dec 2025: $75m (Revenue)RevenueSep 2018: $36m (R&D expense)Dec 2019: $105m (R&D expense)Dec 2023: $130m (R&D expense)Dec 2024: $138m (R&D expense)Dec 2025: $118m (R&D expense)R&D expense
RevenueR&D expense
Year toRevenueR&DR&D %Net incomeFiling
Dec 2025$75.4m$118m156.1%−$288m10-K 2026
Dec 2024$10.1m$138m>999%−$221m10-K 2025
Dec 2023$1.7m$130m>999%−$208m10-K 2025
Dec 2019$2.9m$105m>999%−$124m20-F 2020
Sep 2018$1.4m$36.2m>999%−$44.8m20-F 2020

Each year is taken from the most recent annual report that includes it, so earlier years reflect any later restatement. Source: SEC EDGAR (XBRL financial data). Compare companies on the pharma company financials register.

In the News

No coverage yet — our newsroom tracks Autolus Therapeutics continuously.

Research Publications

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FDA Recalls (US)

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