Ireland
--:--IST
Latest
Priya Life Science Clinical trial register
TrackersDrugsComparisonsAPI
Trackers› Clinical trials› California
Clinical trial register · United States · industry-sponsored

Clinical Trials in California, 2026

Every industry-sponsored study on the ClinicalTrials.gov registry that lists a US site and is open, about to open, active-but-closed, or enrolling by invitation. This deliberately excludes academic and other non-industry sponsors — the full US registry across all sponsors runs to over 22,000 recruiting studies alone.

Download CSV
Source: ClinicalTrials.gov. Complete coverage of the industry-sponsored slice — all 9112 matching records are in this view (non-industry sponsors are out of scope by design, not truncated). Synced 04 Oct 2026, 03:16 UTC
9112
Studies in scope
industry-sponsored, all four open statuses
4948
Recruiting now
open to new participants
2193
Lead sponsors
across recruiting studies
Top states
California 14 Florida 13 Texas 10 New York 10 Ohio 9
Narrow the registerReset
Recruitment status
Phase
Target enrolment
to

Trials with a site in California

14 of 9112 studies
Download
Status
Study
Lead sponsor
Phase
Enrol
US states
Start
Recruiting
Evaluation of the Safety and Efficacy of Abenacianine (VGT-309) to Identify Cancer in Subjects Undergoing Surgery for Cancer in the Lung
NCT07499674Lung Cancer, Lung Metastases
Vergent Bioscience, Inc.
Phase 3
132
California, Colorado, Florida, Michigan, Minnesota, Pennsylvania, Texas
2026-03-31
Active, closed
A Study to Assess Zipalertinib Versus Placebo in Participants With Early Stage NSCLC With Uncommon EGFR Mutations, Following Complete Tumor Resection
NCT07128199Lung Cancer, Adjuvant, Post-surgical, EGFR
Taiho Oncology, Inc.
Phase 3
360
Alaska, California, District of Columbia, Florida, Georgia, Illinois, Michigan, New Jersey
2025-12-22
Active, closed
A Clinical Study of Pembrolizumab (+) Berahyaluronidase Alfa (MK-3475A) to Treat Newly-diagnosed Metastatic Non-small Cell Lung Cancer (MK-3475A-F84)
NCT06698042Lung Cancer, Non-Small Cell Lung Cancer
Merck Sharp & Dohme LLC
Phase 3
67
California, Illinois, New York, Ohio
2024-11-21
Active, closed
A Study of Valemetostat Tosylate Plus Pembrolizumab Versus Pembrolizumab Alone in First-Line NSCLC Without Actionable Genomic Alterations
NCT06644768Non-small Cell Lung Cancer, Lung Cancer
Daiichi Sankyo
Phase 1/2
137
California, Florida, Kentucky, Minnesota, New York, Pennsylvania, Virginia
2024-10-30
Active, closed
Oncolytic Adenovirus TILT-123 With Pembrolizumab as Treatment for Refractory Non-Small Cell Lung Cancer
NCT06125197Lung Cancer
TILT Biotherapeutics Ltd.
Phase 1
22
California
2024-07-23
Recruiting
Safety and Efficacy of OBX-115 in Advanced Solid Tumors
NCT06060613Tumor Skin, Metastatic Melanoma, Melanoma, Lung Cancer
Obsidian Therapeutics, Inc.
Phase 1/2
208
California, Florida, Kentucky, New York, Ohio, Pennsylvania, Texas
2023-10-25
Active, closed
Study of TNG260 and an Anti-PD Antibody in STK11 Mutated Solid Tumors
NCT05887492Non Small Cell Lung Cancer, Solid Tumors, Adult, Lung Cancer, Lung Adenocarcinoma
Tango Therapeutics, Inc.
Phase 1/2
126
California, Colorado, Florida, Massachusetts, Michigan, New York, Tennessee, Texas
2023-06-12
Active, closed
A Dose Escalation Study of HBI-2438 in Patients With Solid Tumors Harboring KRAS G12C Mutation
NCT05485974Lung Cancer, Non Small Cell Lung Cancer, Colorectal Cancer, Cancer of Pancreas
HUYABIO International, LLC.
Phase 1
44
California, Florida, Michigan, Missouri, Ohio
2022-08-01
Active, closed
CASCADE-LUNG: Cancer Screening Assay Using DELFI; A Clinical Validation Study in Lung
NCT05306288Lung Cancer
Delfi Diagnostics Inc.
Observational
11,935
Alabama, California, Colorado, Connecticut, Florida, Georgia, Illinois, Kentucky
2022-04-07
Active, closed
Screening for High Frequency Malignant Disease
NCT05117840Lung Cancer
Guardant Health, Inc.
Observational
12,000
Alabama, Arkansas, California, Connecticut, District of Columbia, Florida, Georgia, Illinois
2022-01-13
Recruiting
A Trial of RSC-1255 for Treatment of Patients With Advanced Malignancies
NCT04678648Advanced Malignant Solid Neoplasm, RAS Mutation, Lung Cancer, Colon Cancer
RasCal Therapeutics, Inc.
Phase 1
134
California, Colorado, Tennessee
2021-03-03
Recruiting
VMD-928 Monotherapy and in Combination With Pembrolizumab to Treat TrkA Overexpression Driven Solid Tumors or Lymphoma
NCT03556228Head and Neck Carcinoma, Adenoid Cystic Carcinoma, Lung Cancer, Non-Small Cell Lung Cancer
VM Oncology, LLC
Phase 1/2
242
California, Connecticut, District of Columbia, Florida, New Jersey, New Mexico, New York, Ohio
2018-06-08
Active, closed
An Open-Label Study to Enable Continued Treatment Access for Subjects Previously Enrolled in Studies of Ruxolitinib
NCT02955940Pancreatic Cancer, Colorectal Cancer (CRC), Breast Cancer, Lung Cancer
Incyte Corporation
Phase 2
10
California, Kentucky, New York, Tennessee, Texas
2016-11-30
Rows per page Showing 1–14 of 14
1
Cite this view

Priya Life Science (2026). Clinical trial register: industry-sponsored studies with a US investigative site, filtered. Derived from ClinicalTrials.gov. Retrieved 4 October 2026. https://priyalifescience.com/clinical-trials-usa/state/california

Query this register directly
GET /api/trials?country=usa&status=recruiting&format=json Try it now →

About this register

This register is built from ClinicalTrials.gov, the trial registry run by the U.S. National Library of Medicine. It includes every industry-sponsored study on the registry that lists at least one investigative site in the US and is recruiting, not yet recruiting, active but no longer recruiting, or enrolling by invitation: 9,112 studies in total at the last sync on 04 Oct 2026, 03:16 UTC. Academic and other non-industry sponsors are out of scope by design. The full list can be downloaded as CSV or queried as JSON through the register API.

This page shows the 14 of those studies with a site in California that also match the filters currently applied.

How many clinical trials are recruiting in California?

4 of the 14 studies on this page are recruiting new participants as of the 04 Oct 2026, 03:16 UTC sync. A further 0 have not yet opened recruitment, 10 are active but closed to new participants, and 0 are enrolling by invitation only. Eligibility for any study is decided by its study team.

Summary by phase

Studies by phase (California), 14 studies
PhaseStudiesRecruitingShare
Phase 1/24228.6%
Phase 13121.4%
Phase 33121.4%
Observational2014.3%
Phase 22014.3%

Most active sponsors

Lead sponsors with the most studies (California)
Lead sponsorStudiesRecruiting
AstraZeneca10
Daiichi Sankyo10
Delfi Diagnostics Inc.10
Guardant Health, Inc.10
HUYABIO International, LLC.10
Incyte Corporation10
Merck Sharp & Dohme LLC10
Obsidian Therapeutics, Inc.11
RasCal Therapeutics, Inc.11
Taiho Oncology, Inc.10
Listing here is informational and not medical advice; eligibility is determined by each study team. Compare pay for the teams running these studies in the US Pharma Salary Guide, see who's behind them in the US Company Directory, or track approvals on the FDA Approvals Tracker. For Irish, UK and EU sites, see the Ireland, UK and EU registers.