Orforglipron: Administered orally
Placebo: Administered orally
The purpose of this Master Protocol is to support two studies to see how well and how safely orforglipron works compared to placebo in participants who have obesity or overweight with or without type 2 diabetes. Participants will be screened for about 4 weeks, after which they will enroll into either J2A-MC-GZP1, NCT06972459 (do not have type 2 diabetes) or J2A-MC-GZP2, NCT06972472 (have type 2 diabetes).
| Facility | City | Region | Status |
|---|---|---|---|
| Clinical Research Institute of Arizona (CRI) - Sun City West | Sun City West | Arizona | |
| Novak Clinical Research - Tucson - North La Cholla Boulevard | Tucson | Arizona | |
| Norcal Endocrinology & Internal Medicine | San Ramon | California | |
| Southern California Clinical Research | Santa Ana | California | |
| Care Access - Thousand Oaks | Thousand Oaks | California | |
| Accel Research Sites - DeLand Clinical Research Unit | DeLand | Florida | |
| Innovation Medical Research Center - Fort Lauderdale | Fort Lauderdale | Florida | |
| Indago Research & Health Center, Inc | Hialeah | Florida | |
| Encore Medical Research | Hollywood | Florida | |
| West Orange Endocrinology P.A. | Ocoee | Florida | |
| Care Access - Tampa | Tampa | Florida | |
| Conquest Research | Winter Park | Florida | |
| Accel Research Sites - NeuroStudies Clinical Research Unit | Decatur | Georgia | |
| Care Access - Decatur | Decatur | Georgia | |
| Javara - Privia Medical Group Georgia - Savannah | Savannah | Georgia | |
| North Georgia Clinical Research | Woodstock | Georgia | |
| Solaris Clinical Research | Meridian | Idaho | |
| Care Access - New Iberia | New Iberia | Louisiana | |
| Endocrine and Metabolic Consultants | Rockville | Maryland | |
| Javara - Privia Medical Group - Silver Spring | Silver Spring | Maryland | |
| Great Lakes Research Group, Inc. | Bay City | Michigan | |
| Boeson Research MSO | Missoula | Montana | |
| Javara - Nevada Health Centers - Carson City | Carson City | Nevada | |
| The Machuca Foundation | Las Vegas | Nevada | |
| University of North Carolina Medical Center | Chapel Hill | North Carolina | |
| Javara - Tryon Medical Partners | Charlotte | North Carolina | |
| Care Access - Fayetteville | Fayetteville | North Carolina | |
| The Corvallis Clinic, P.C. | Corvallis | Oregon | |
| Clinical Research of Philadelphia | Philadelphia | Pennsylvania | |
| Frontier Clinical Research, LLC | Smithfield | Pennsylvania | |
| Velocity Clinical Research, Dallas | Dallas | Texas | |
| Biopharma Informatic, LLC | Houston | Texas | |
| Activian Clinical Research | Kingwood | Texas | |
| Texas Valley Clinical Research (TVCR) - Mission | Mission | Texas | |
| Consano Clinical Research, LLC | Shavano Park | Texas | |
| CARE - Centro de Alergia y Enfermedades Respiratorias | Buenos Aires | Argentina | |
| CIPREC | Buenos Aires | Argentina | |
| Centro Médico Viamonte | Buenos Aires | Argentina | |
| Instituto Centenario | CABA | Argentina | |
| Instituto Médico Catamarca IMEC | Rosario | Argentina |
+ 40 more sites — see the full list on the official registry below.
This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
View NCT06993792 on ClinicalTrials.gov ↗ ← All trials in the USA