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Trackers› Clinical trials› Ulcerative Colitis (UC)
Clinical trial register · United States · industry-sponsored

Ulcerative Colitis (UC) Trials in the USA

Every industry-sponsored study on the ClinicalTrials.gov registry that lists a US site and is open, about to open, active-but-closed, or enrolling by invitation. This deliberately excludes academic and other non-industry sponsors — the full US registry across all sponsors runs to over 22,000 recruiting studies alone.

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Source: ClinicalTrials.gov. Complete coverage of the industry-sponsored slice — all 9094 matching records are in this view (non-industry sponsors are out of scope by design, not truncated). Synced 17 Sep 2026, 08:23 UTC
9094
Studies in scope
industry-sponsored, all four open statuses
4935
Recruiting now
open to new participants
2188
Lead sponsors
across recruiting studies
Top states
Florida 8 California 6 Arizona 5 Colorado 5 Connecticut 4
Narrow the registerReset
Recruitment status
Phase
Lead sponsor
AbbVie3 Rubix LS1 Eli Lilly and Company1 AltruBio Inc.1 Ono Pharmaceutical Co., Ltd.1
State
Florida8 California6 Arizona5 Colorado5 Connecticut4
All 21 states
Target enrolment
to
10 of 9094 studies
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Status
Study
Lead sponsor
Phase
Enrol
US states
Start
Recruiting
Study to Evaluate the Efficacy and Safety of Ponesimod (VSP-128) in Patients With Moderately to Severely Active Ulcerative Colitis
NCT07686081Ulcerative Colitis (UC)
Vanda Pharmaceuticals
Phase 3
150
California, Tennessee
2026-09
Recruiting
A Study to Investigate the Safety, Tolerability, and Pharmacokinetics of ONO-6414 Administered Orally in Healthy Adult Participants and Patients With Active Ulcerative Colitis
NCT07749768Ulcerative Colitis (UC)
Ono Pharmaceutical Co., Ltd.
Phase 1
90
Florida
2026-08-20
Recruiting
LY4268989 in Adults With Moderately to Severely Active Ulcerative Colitis
NCT07415044Ulcerative Colitis (UC), Ulcerative Colitis, Active Moderate, Ulcerative Colitis, Active Severe
Eli Lilly and Company
Phase 2
1,431
Arizona, California, Colorado, Connecticut, Florida, Idaho, Illinois, Indiana
2026-03-26
Active, closed
Evaluate the Safety, Tolerability, PK and PD of SAD of Intravenously Adminsterted ALTB-268 in Healthy Participants
NCT07350577Ulcerative Colitis (UC)
AltruBio Inc.
Phase 1
24
Florida
2025-11-17
Not yet open
Evaluating the Efficacy and Safety of Mirikizumab in Adults Over 60 With Moderate to Severe Crohn's Disease and Ulcerative Colitis
NCT07059130Crohn Disease (CD), Crohns Disease, Ulcerative Colitis (UC)
Rubix LS
Phase 4
150
Massachusetts
2025-07-16
Recruiting
A Phase 2 Study to Evaluate Therapies for Inflammatory Bowel Disease
NCT07113522Inflammatory Bowel Disease (IBD), Ulcerative Colitis (UC), Crohn's Disease
Mirador Therapeutics, Inc.
Phase 2
140
Alabama, Arizona, Arkansas, Colorado, Florida, Georgia, Illinois, Louisiana
2025-06-26
Recruiting
Study of XmAb942 in Healthy Participants and Participants With Ulcerative Colitis
NCT06619990Ulcerative Colitis (UC)
Xencor, Inc.
Phase 1/2
270
Arizona, California, Florida, Kentucky, Mississippi, New York, North Carolina, Ohio
2024-10-10
Active, closed
A Study to Assess the Efficacy and Safety of Risankizumab in Participants With Ulcerative Colitis
NCT03398135Ulcerative Colitis (UC)
AbbVie
Phase 3
1,242
California, Colorado, Connecticut, Florida, Georgia, Illinois, Indiana, Kansas
2018-08-28
Active, closed
A Study to Evaluate the Long-Term Safety and Efficacy of Upadacitinib (ABT-494) in Participants With Ulcerative Colitis (UC)
NCT03006068Ulcerative Colitis (UC)
AbbVie
Phase 3
950
Alabama, Arizona, California, Colorado, Connecticut, Florida, Georgia, Illinois
2017-01-31
Active, closed
A Long-Term Registry of Humira® (Adalimumab) in Patients With Moderately to Severely Active Ulcerative Colitis (UC)
NCT01848561Ulcerative Colitis (UC)
AbbVie
Observational
8,250
Alabama, Arizona, Arkansas, California, Colorado, Connecticut, District of Columbia, Florida
2013-04-29
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Cite this view

Priya Life Science (2026). Clinical trial register: industry-sponsored studies with a US investigative site, filtered. Derived from ClinicalTrials.gov. Retrieved 17 September 2026. https://priyalifescience.com/clinical-trials-usa/condition/ulcerative-colitis-uc

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Listing here is informational and not medical advice; eligibility is determined by each study team. Compare pay for the teams running these studies in the US Pharma Salary Guide, see who's behind them in the US Company Directory, or track approvals on the FDA Approvals Tracker. For Irish, UK and EU sites, see the Ireland, UK and EU registers.