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Priya Life Science Clinical trial register
Trackers› Clinical trials› Systemic Sclerosis (SSc)
Clinical trial register · United States · industry-sponsored

Systemic Sclerosis (SSc) Trials in the USA, 2026

Every industry-sponsored study on the ClinicalTrials.gov registry that lists a US site and is open, about to open, active-but-closed, or enrolling by invitation. This deliberately excludes academic and other non-industry sponsors — the full US registry across all sponsors runs to over 22,000 recruiting studies alone.

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Source: ClinicalTrials.gov. Complete coverage of the industry-sponsored slice — all 9128 matching records are in this view (non-industry sponsors are out of scope by design, not truncated). Synced 04 Nov 2026, 03:16 UTC
9128
Studies in scope
industry-sponsored, all four open statuses
4968
Recruiting now
open to new participants
2189
Lead sponsors
across recruiting studies
Top states
California 5 Florida 4 Arizona 3 Illinois 2 Iowa 2
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Recruitment status
Phase
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Systemic Sclerosis (SSc) trials in the USA

8 of 9128 studies
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Status
Study
Lead sponsor
Phase
Enrol
US states
Start
Not yet open
C-CAR168, an Autologous Anti-CD20/BCMA Chimeric Antigen Receptor T-Cell Therapy, in Participants With Systemic Sclerosis (SSc) Refractory to Standard Therapy
NCT07854483Systemic Sclerosis (SSc), Systemic Sclerosis, Systemic Sclerosis (Scleroderma), Systemic Sclerosis - 2013 ACR/EULAR Classification Criteria
AbelZeta Inc.
Phase 1
12
Arizona
2027-03
Not yet open
BAFF CAR-T Cells (LMY-922) for Treatment of Refractory Autoimmune Disease
NCT07729995Rheumatoid Arthritis (RA), Systemic Lupus Erthematosus (SLE), Dermatomyositis (DM), Systemic Sclerosis (SSc)
Luminary Therapeutics
Phase 1
94
Massachusetts
2026-10
Recruiting
US Zamto-cel Autoimmune Diseases
NCT06708845Lupus Nephritis, Systemic Lupus Erythematosus, Systemic Sclerosis (SSc), Diffuse Cutaneous Systemic Sclerosis
Miltenyi Biomedicine GmbH
Phase 1
48
Wisconsin
2026-07
Recruiting
AlloNK®, an Allogeneic Non-genetically Modified, Cord Blood-derived NK Cell Therapy, in Combination With Rituximab, Studied in Relapsing Forms of B-cell Dependent Rheumatologic Diseases.
NCT06991114Refractory Rheumatoid Arthritis (RA), Idiopathic Inflammatory Myopathies (IIMs), Systemic Sclerosis (SSc), Rheumatoid Arthritis (RA
Artiva Biotherapeutics, Inc.
Phase 2
90
Alabama, Arizona, California, Florida, Georgia, Illinois, Iowa, Montana
2025-07-09
Active, closed
Zura Bio Inc
Phase 2
80
California, Florida, Iowa, Massachusetts, Michigan, Texas
2025-02-06
Active, closed
argenx
Phase 2
87
Arizona, California, Florida, Illinois, Louisiana, Maryland, Michigan, Pennsylvania
2024-11-11
By invitation
A Phase 1 Study of Prulacabtagene Leucel (Prula-cel, Formerly ADI-001) in Autoimmune Disease
NCT06375993Lupus Nephritis, Autoimmune Diseases, Systemic Sclerosis (SSc), Systemic Lupus Erythematosus (SLE)
Adicet Therapeutics
Phase 1
180
California, New York
2024-11-10
Recruiting
A Phase 1 Study of FT819 in B-cell Mediated Autoimmune Disease
NCT06308978Antineutrophilic Cytoplasmic Antibody (ANCA)- Associated Vasculitis (AAV), Idiopathic Inflammatory Myositis (IIM), Systemic Sclerosis (SSc), Systemic Lupus Erythematosus (SLE)
Fate Therapeutics
Phase 1
244
California, Florida, Kentucky, Minnesota, Nebraska, New York, North Carolina, Ohio
2024-03-28
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Cite this view

Priya Life Science (2026). Clinical trial register: industry-sponsored studies with a US investigative site, filtered. Derived from ClinicalTrials.gov. Retrieved 4 November 2026. https://priyalifescience.com/clinical-trials-usa/condition/systemic-sclerosis-ssc

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About this register

This register is built from ClinicalTrials.gov, the trial registry run by the U.S. National Library of Medicine. It includes every industry-sponsored study on the registry that lists at least one investigative site in the US and is recruiting, not yet recruiting, active but no longer recruiting, or enrolling by invitation: 9,128 studies in total at the last sync on 04 Nov 2026, 03:16 UTC. Academic and other non-industry sponsors are out of scope by design. The full list can be downloaded as CSV or queried as JSON through the register API.

This page shows the 8 of those studies listing the condition Systemic Sclerosis (SSc).

How many Systemic Sclerosis (SSc) trials are recruiting in the US?

3 of the 8 studies on this page are recruiting new participants as of the 04 Nov 2026, 03:16 UTC sync. A further 2 have not yet opened recruitment, 2 are active but closed to new participants, and 1 are enrolling by invitation only. Eligibility for any study is decided by its study team.

Summary by phase

Studies by phase (Systemic Sclerosis (SSc)), 8 studies
PhaseStudiesRecruitingShare
Phase 15262.5%
Phase 23137.5%

Most active sponsors

Lead sponsors with the most studies (Systemic Sclerosis (SSc))
Lead sponsorStudiesRecruiting
AbelZeta Inc.10
Adicet Therapeutics10
argenx10
Artiva Biotherapeutics, Inc.11
Fate Therapeutics11
Luminary Therapeutics10
Miltenyi Biomedicine GmbH11
Zura Bio Inc10

Top states

Top states (Systemic Sclerosis (SSc)), by number of studies with a site there
StateStudies
California5
Florida4
Arizona3
Illinois2
Iowa2
Massachusetts2
Michigan2
New York2
Alabama1
Georgia1
Listing here is informational and not medical advice; eligibility is determined by each study team. Compare pay for the teams running these studies in the US Pharma Salary Guide, see who's behind them in the US Company Directory, or track approvals on the FDA Approvals Tracker. For Irish, UK and EU sites, see the Ireland, UK and EU registers.