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Trackers› Clinical trials› Plaque Psoriasis
Clinical trial register · United States · industry-sponsored

Plaque Psoriasis Trials in the USA

Every industry-sponsored study on the ClinicalTrials.gov registry that lists a US site and is open, about to open, active-but-closed, or enrolling by invitation. This deliberately excludes academic and other non-industry sponsors — the full US registry across all sponsors runs to over 22,000 recruiting studies alone.

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Source: ClinicalTrials.gov. Complete coverage of the industry-sponsored slice — all 9094 matching records are in this view (non-industry sponsors are out of scope by design, not truncated). Synced 17 Sep 2026, 08:23 UTC
9094
Studies in scope
industry-sponsored, all four open statuses
4935
Recruiting now
open to new participants
2188
Lead sponsors
across recruiting studies
Top states
California 17 Florida 17 Illinois 14 Arizona 12 Arkansas 9
Narrow the registerReset
Recruitment status
Phase
Lead sponsor
Janssen Research & Development, LLC5 Oruka Therapeutics, Inc.4 Takeda2 Bristol-Myers Squibb2 Alumis Inc2
State
California17 Florida17 Illinois14 Arizona12 Arkansas9
All 25 states
Target enrolment
to
18 of 9094 studies
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Status
Study
Lead sponsor
Phase
Enrol
US states
Start
Recruiting
Dose Ranging Study of ORKA-002 in Patients With Moderate-to-Severe Plaque Psoriasis
NCT07474792Plaque Psoriasis
Oruka Therapeutics, Inc.
Phase 2
160
Alabama, Arizona, California, Connecticut, Florida, Illinois, Massachusetts, Michigan
2026-03-19
Recruiting
An Open-Label Extension Study of ORKA-001 in Participants With Plaque Psoriasis
NCT07449702Plaque Psoriasis
Oruka Therapeutics, Inc.
Phase 2
240
Arizona, California, Connecticut, Florida, Illinois, Kentucky, Maryland, Massachusetts
2026-02-23
Recruiting
A Long-Term Study of Zasocitinib in Children and Teenagers With Plaque Psoriasis
NCT07250802Plaque Psoriasis
Takeda
Phase 3
110
California, Florida, Illinois, Ohio, South Carolina, Texas, Wisconsin
2025-12-04
Active, closed
Dose Ranging Study of ORKA-001 in Patients With Moderate-to-Severe Plaque Psoriasis
NCT07290569Plaque Psoriasis
Oruka Therapeutics, Inc.
Phase 2
160
Arizona, Arkansas, California, Florida, Illinois, Indiana, Maryland, New York
2025-12-03
Recruiting
A Study to Evaluate the Efficacy, Safety, and Drug Levels of Deucravacitinib (BMS-986165) in Adolescent Participants With Moderate to Severe Plaque Psoriasis
NCT06979453Plaque Psoriasis
Bristol-Myers Squibb
Phase 3
366
Alabama, Arizona, California, Colorado, Florida, Georgia, Idaho, Indiana
2025-12-03
Recruiting
Long-Term Safety Study of Deucravacitinib Versus Ustekinumab in Participants With Psoriasis (PRAGMATYK)
NCT07116967Plaque Psoriasis
Bristol-Myers Squibb
Phase 3
3,040
Alabama, Arizona, Arkansas, California, Colorado, District of Columbia, Florida, Georgia
2025-09-22
Active, closed
ORKA-001 Versus Placebo in Patients With Moderate-to-Severe Plaque Psoriasis
NCT07090330Plaque Psoriasis
Oruka Therapeutics, Inc.
Phase 2
80
California, Connecticut, Florida, Illinois, Kentucky, Maryland, Massachusetts, Michigan
2025-07-18
Recruiting
A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Efficacy of ASC50 Tables in Healthy Participants and Participants With Plaque Psoriasis
NCT07024602Plaque Psoriasis
Ascletis Pharma (China) Co., Limited
Phase 1
94
Florida
2025-06
Active, closed
A Study to Assess Efficacy and Safety of JNJ-77242113 Compared to Placebo and Ustekinumab in Participants With Moderate to Severe Plaque Psoriasis
NCT06934226Plaque Psoriasis
Janssen Research & Development, LLC
Phase 3
752
Alabama, California, Connecticut, Florida, Georgia, Illinois, Indiana, Iowa
2025-04-15
Not yet open
Understanding Participation Habits Among Plaque Psoriasis Patients
NCT06338358Plaque Psoriasis
Power Life Sciences Inc.
Observational
500
California
2025-04
Active, closed
Long-term Safety and Efficacy of ESK-001 in Moderate to Severe Plaque Psoriasis
NCT06846541Plaque Psoriasis, Psoriasis (PsO), Psoriasis, Moderate Psoriasis
Alumis Inc
Phase 3
1,680
Alabama, Arizona, Arkansas, California, Florida, Illinois, Indiana, Kentucky
2025-01-08
Active, closed
A Study of TAK-279 in Participants With Moderate-to-Severe Plaque Psoriasis
NCT06550076Plaque Psoriasis
Takeda
Phase 3
2,099
Alabama, Arizona, Arkansas, California, Florida, Georgia, Idaho, Illinois
2024-09-04
Active, closed
A Study of JNJ-77242113 for the Treatment of Participants With Moderate to Severe Plaque Psoriasis (ICONIC-ADVANCE 2)
NCT06220604Plaque Psoriasis
Janssen Research & Development, LLC
Phase 3
731
Arizona, California, Florida, Georgia, Illinois, Kentucky, Maryland, Massachusetts
2024-03-09
Active, closed
A Study of JNJ-77242113 for the Treatment of Participants With Moderate to Severe Plaque Psoriasis
NCT06143878Plaque Psoriasis
Janssen Research & Development, LLC
Phase 3
774
Arizona, Arkansas, California, Florida, Georgia, Illinois, Indiana, Kentucky
2024-02-01
Active, closed
A Study of JNJ-77242113 for the Treatment of Participants With Plaque Psoriasis Involving Special Areas (Scalp, Genital, and/or Palms of the Hands and the Soles of the Feet)
NCT06095102Plaque Psoriasis
Janssen Research & Development, LLC
Phase 3
311
Arizona, Arkansas, California, Florida, Georgia, Illinois, Indiana, Louisiana
2023-10-12
Active, closed
A Study of JNJ-77242113 in Adolescent and Adult Participants With Moderate to Severe Plaque Psoriasis
NCT06095115Plaque Psoriasis
Janssen Research & Development, LLC
Phase 3
684
Arizona, Arkansas, California, Florida, Georgia, Illinois, Indiana, Kentucky
2023-10-12
Active, closed
Open-Label Extension Study to Evaluate the Long Term Safety and Efficacy of ESK-001 in Plaque Psoriasis
NCT05739435Plaque Psoriasis
Alumis Inc
Phase 2
165
Alabama, Arizona, Arkansas, California, Florida, Georgia, Illinois, Indiana
2023-01-17
Active, closed
Tapinarof for the Treatment of Plaque Psoriasis in Pediatric Subjects
NCT05172726Plaque Psoriasis
Organon and Co
Phase 3
58
Arkansas, California, Florida, Illinois, Indiana, Ohio, Oregon, Washington
2021-12-02
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Cite this view

Priya Life Science (2026). Clinical trial register: industry-sponsored studies with a US investigative site, filtered. Derived from ClinicalTrials.gov. Retrieved 17 September 2026. https://priyalifescience.com/clinical-trials-usa/condition/plaque-psoriasis

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Listing here is informational and not medical advice; eligibility is determined by each study team. Compare pay for the teams running these studies in the US Pharma Salary Guide, see who's behind them in the US Company Directory, or track approvals on the FDA Approvals Tracker. For Irish, UK and EU sites, see the Ireland, UK and EU registers.