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Priya Life Science Clinical trial register
Trackers› Clinical trials› Hereditary Angioedema (HAE)
Clinical trial register · United States · industry-sponsored

Hereditary Angioedema (HAE) Trials in the USA, 2026

Every industry-sponsored study on the ClinicalTrials.gov registry that lists a US site and is open, about to open, active-but-closed, or enrolling by invitation. This deliberately excludes academic and other non-industry sponsors — the full US registry across all sponsors runs to over 22,000 recruiting studies alone.

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Source: ClinicalTrials.gov. Complete coverage of the industry-sponsored slice — all 9128 matching records are in this view (non-industry sponsors are out of scope by design, not truncated). Synced 04 Nov 2026, 03:16 UTC
9128
Studies in scope
industry-sponsored, all four open statuses
4968
Recruiting now
open to new participants
2189
Lead sponsors
across recruiting studies
Top states
California 6 Arkansas 5 Maryland 5 Missouri 5 Arizona 4
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Recruitment status
Phase
Target enrolment
to

Hereditary Angioedema (HAE) trials in the USA

7 of 9128 studies
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Status
Study
Lead sponsor
Phase
Enrol
US states
Start
Recruiting
Ionis Pharmaceuticals, Inc.
Phase 3
20
California, Florida, Louisiana, Missouri, Ohio, Pennsylvania, Wisconsin
2026-04-21
Recruiting
Phase 3 Extension Study of ADX-324 in Participants With Hereditary Angioedema (HAE)
NCT07428499Hereditary Angioedema (HAE), Hereditary Angioedema - Type 1, Hereditary Angioedema - Type 2, HAE
ADARx Pharmaceuticals, Inc.
Phase 3
90
Arizona, Arkansas, California, Florida, Maryland, Michigan, Missouri, Nevada
2026-04-02
By invitation
Astria Therapeutics, Inc.
Phase 3
145
Arizona, Arkansas, California, Colorado, Maryland, Ohio, Pennsylvania
2025-10-01
Active, closed
Astria Therapeutics, Inc.
Phase 3
157
Alabama, Arizona, Arkansas, California, Colorado, Florida, Maryland, Massachusetts
2025-03-20
Active, closed
A Phase 2 in Adult Subjects With Hereditary Angioedema
NCT06846398Hereditary Angioedema (HAE)
Shanghai Argo Biopharmaceutical Co., Ltd.
Phase 2
25
Maryland, Missouri, North Carolina, Pennsylvania, Virginia
2025-02-28
By invitation
Pharvaris Netherlands B.V.
Phase 3
170
Alabama, Arizona, Arkansas, California, Colorado, Illinois, Missouri, Nevada
2025-02-01
Active, closed
Pharvaris Netherlands B.V.
Phase 3
81
Arkansas, California, Maryland, Missouri
2024-12-01
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1
Cite this view

Priya Life Science (2026). Clinical trial register: industry-sponsored studies with a US investigative site, filtered. Derived from ClinicalTrials.gov. Retrieved 4 November 2026. https://priyalifescience.com/clinical-trials-usa/condition/hereditary-angioedema-hae

Query this register directly
GET /api/trials?country=usa&status=recruiting&format=json Try it now →

About this register

This register is built from ClinicalTrials.gov, the trial registry run by the U.S. National Library of Medicine. It includes every industry-sponsored study on the registry that lists at least one investigative site in the US and is recruiting, not yet recruiting, active but no longer recruiting, or enrolling by invitation: 9,128 studies in total at the last sync on 04 Nov 2026, 03:16 UTC. Academic and other non-industry sponsors are out of scope by design. The full list can be downloaded as CSV or queried as JSON through the register API.

This page shows the 7 of those studies listing the condition Hereditary Angioedema (HAE).

How many Hereditary Angioedema (HAE) trials are recruiting in the US?

2 of the 7 studies on this page are recruiting new participants as of the 04 Nov 2026, 03:16 UTC sync. A further 0 have not yet opened recruitment, 3 are active but closed to new participants, and 2 are enrolling by invitation only. Eligibility for any study is decided by its study team.

Summary by phase

Studies by phase (Hereditary Angioedema (HAE)), 7 studies
PhaseStudiesRecruitingShare
Phase 36285.7%
Phase 21014.3%

Most active sponsors

Lead sponsors with the most studies (Hereditary Angioedema (HAE))
Lead sponsorStudiesRecruiting
Astria Therapeutics, Inc.20
Pharvaris Netherlands B.V.20
ADARx Pharmaceuticals, Inc.11
Ionis Pharmaceuticals, Inc.11
Shanghai Argo Biopharmaceutical Co., Ltd.10

Top states

Top states (Hereditary Angioedema (HAE)), by number of studies with a site there
StateStudies
California6
Arkansas5
Maryland5
Missouri5
Arizona4
Colorado3
Florida3
Pennsylvania3
Alabama2
Nevada2
Listing here is informational and not medical advice; eligibility is determined by each study team. Compare pay for the teams running these studies in the US Pharma Salary Guide, see who's behind them in the US Company Directory, or track approvals on the FDA Approvals Tracker. For Irish, UK and EU sites, see the Ireland, UK and EU registers.