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Updated 05 Aug 2026 · ClinicalTrials.gov

Clinical Trials in the USA

The most recently updated industry-sponsored clinical trials recruiting across the United States — searchable by condition, sponsor, phase and state. Refreshed daily from the ClinicalTrials.gov registry.

103
Recruiting now
160
Studies tracked
47
States with sites
Starting soon Phase 3
A Study of Secutrelvir in Participants With Coronavirus Disease 2019 (COVID-19) Who Are at High Risk for Progression to Severe Disease
SARS-CoV-2
Shionogi · started 2026-08-06
📍 Florida · Ohio
NCT07743580 on ClinicalTrials.gov ↗
Starting soon
Radicle Energy™ DNB: A Study Assessing the Impact of Health and Wellness Products on Fatigue and Related Health Outcomes
Fatigue
Radicle Science · started 2026-08-13
📍 California
NCT07745010 on ClinicalTrials.gov ↗
Recruiting Phase 3
CAPRI: A Phase 3 Randomized, Double-Masked Study Comparing the Efficacy of EYP-1901 Against Aflibercept in DME
Diabetic Macular Edema, DME, Diabetic Macular Edema (DME)
EyePoint Pharmaceuticals, Inc. · started 2026-02-09
📍 Arizona · California · Colorado · Connecticut · Florida · Illinois · Indiana · Kentucky
NCT07449923 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Study to Assess Change in Disease Activity and Adverse Events of Oral Upadacitinib in Adult and Adolescent Participants With Moderate to Severe Hidradenitis Suppurativa Who Have Failed Anti-TNF Therapy
Hidradenitis Suppurativa
AbbVie · started 2023-06-21
📍 Alabama · Arizona · Arkansas · California · Connecticut · Florida · Georgia · Idaho
NCT05889182 on ClinicalTrials.gov ↗
Recruiting Phase 2
PUL-042 Treatment in Patients With Parainfluenza Virus (PIV), Human Metapneumovirus (hMPV) or Respiratory Syncytial Virus (RSV)
Hematologic Malignancies, Hematopoietic Stem Cell Transplant (HSCT)
Pulmotect, Inc. · started 2025-06-27
📍 California · Georgia · Maryland · Massachusetts · Michigan · Minnesota · New Jersey · New York
NCT06665100 on ClinicalTrials.gov ↗
Recruiting Phase 3
Maridebart Cafraglutide Versus Placebo in Adult Participants With Obstructive Sleep Apnea on Positive Airway Pressure Therapy
Obesity, Obstructive Sleep Apnea
Amgen · started 2025-12-19
📍 California · Florida · Georgia · New York · North Carolina · Ohio · Texas · Washington
NCT07225686 on ClinicalTrials.gov ↗
Active Phase 2
An Open-label, Phase 2 Study of ACP-196 (Acalabrutinib) in Subjects With Mantle Cell Lymphoma
Mantle Cell Lymphoma (MCL)
Acerta Pharma BV · started 2015-03-02
📍 Florida · Illinois · Massachusetts · New Jersey · New York · Texas · Washington
NCT02213926 on ClinicalTrials.gov ↗
Recruiting Phase 1/Phase 2
Phase II IMNN-001 (Also Known as GEN-1) on SLL With BEV and NACT, Newly Diagnosed Advanced Ovarian, Fallopian Tube or Primary Peritoneal Cancer
Ovarian Cancer, Fallopian Tube Cancer, Primary Peritoneal Cancer
Imunon · started 2023-02-10
📍 Maryland · New York · Oklahoma · Texas
NCT05739981 on ClinicalTrials.gov ↗
Active Phase 2
A Study to Test Long-term Treatment With Brigimadlin in People With Solid Tumours Who Took Part in a Previous Study With This Medicine
Solid Tumours
Boehringer Ingelheim · started 2024-12-30
📍 California · Connecticut · Florida · Missouri · Nebraska · New York · Tennessee · Texas
NCT06619509 on ClinicalTrials.gov ↗
Recruiting Phase 1/Phase 2
A Gene Therapy Study of SPK-8011QQ in Adults With Severe or Moderately Severe Hemophilia A
Hemophilia A
Hoffmann-La Roche · started 2026-09-01
📍 California
NCT07226206 on ClinicalTrials.gov ↗
Recruiting Phase 1
A Study to Test How Well Different Doses of BI 3820768 Are Tolerated by People With Advanced Cancer (Solid Tumours)
Advanced Relapsed or Refractory Germ Cell Tumours, Advanced Relapsed or Refractory Endometrial Cancer, Advanced Relapsed or Refractory Ovarian Cancer
Boehringer Ingelheim · started 2026-04-28
📍 California · Indiana · Texas
NCT07306559 on ClinicalTrials.gov ↗
Starting soon Phase 1/Phase 2
Study of TUB-040 in Patients With Recurrent or Progressive Uterine Cancer After Chemotherapy and Immune Therapy
Uterine Endometrial Cancer
Tubulis GmbH · started 2026-10
📍 California · New Jersey · New York · Utah
NCT07743541 on ClinicalTrials.gov ↗
Recruiting Phase 3
Pridopidine Phase 3 Study to Evaluate Efficacy and Safety in ALS
Amyotrophic Lateral Sclerosis
Prilenia · started 2026-02-01
📍 Arizona · California · Colorado · Florida · Georgia · Illinois · Kansas · Maryland
NCT07322003 on ClinicalTrials.gov ↗
Recruiting
Evaluating the Efficacy of OCM™ (Omeza® Complete Matrix) in the Treatment of Diabetic Foot Ulcers
Diabetic Foot Ulcer
Omeza, LLC · started 2025-12-04
📍 Illinois · Louisiana · Mississippi · Ohio
NCT07161830 on ClinicalTrials.gov ↗
Recruiting Phase 2
Study to Assess the Efficacy and Safety of Rina-S in Participants With Advanced Gastrointestinal (GI) Cancers
Gastrointestinal Cancers
Genmab · started 2026-05-11
📍 Michigan · Texas
NCT07539311 on ClinicalTrials.gov ↗
Recruiting Phase 2/Phase 3
Phase 2/3 Adaptive Study of VX-147 in Adult and Pediatric Participants With APOL1-Mediated Proteinuric Kidney Disease
Proteinuric Kidney Disease
Vertex Pharmaceuticals Incorporated · started 2022-03-30
📍 Alabama · Arizona · Arkansas · California · Connecticut · District of Columbia · Florida · Georgia
NCT05312879 on ClinicalTrials.gov ↗
Recruiting
Diuretics Alone vs. Aortix Endovascular Device for Acute Heart Failure
Heart Failure, Cardiorenal Syndrome, Cardio-Renal Syndrome, ADHF
Procyrion · started 2023-08-23
📍 Arizona · California · Florida · Georgia · Illinois · Kansas · Michigan · Mississippi
NCT05677100 on ClinicalTrials.gov ↗
Active Phase 3
A Study to Assess the Change in Disease Activity in Adult Participants With Moderate to Severe Ulcerative Colitis Treated With Risankizumab Compared to Vedolizumab
Ulcerative Colitis
AbbVie · started 2025-06-17
📍 Alabama · Arizona · California · Connecticut · Florida · Georgia · Illinois · Indiana
NCT06880744 on ClinicalTrials.gov ↗
Recruiting Phase 2/Phase 3
A Clinical Study of Islatravir and Ulonivirine for People With HIV-1 Who Have Not Been Treated Before (MK-8591B-062)
Human Immunodeficiency Virus Type 1 (HIV-1) Infection
Merck Sharp & Dohme LLC · started 2025-12-18
📍 California · Colorado · District of Columbia · Florida · Georgia · Illinois · Michigan · Missouri
NCT07266831 on ClinicalTrials.gov ↗
Recruiting Phase 1
A Study in People With Advanced Cancer to Test How Well Different Doses of BI 3819026 Are Tolerated When Taken Alone and Together With Ezabenlimab
Advanced Solid Cancer, Metastatic Solid Cancer
Boehringer Ingelheim · started 2026-05-01
📍 Connecticut · New Jersey · New York · Tennessee
NCT07607678 on ClinicalTrials.gov ↗
Recruiting Phase 2
Phase 2 Study to Assess the Safety and Efficacy of ANG003
Exocrine Pancreatic Insufficiency (EPI), Cystic Fibrosis (CF)
Anagram Therapeutics, Inc. · started 2026-04-24
📍 California · Colorado · Florida · Illinois · Iowa · Kansas · Kentucky · Maine
NCT07450547 on ClinicalTrials.gov ↗
Recruiting Phase 3
AMAZE 2: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Type 2 Diabetes Lose Weight
Diabetes Mellitus, Overweight, Obesity
Novo Nordisk A/S · started 2026-04-13
📍 Alabama · California · Florida · Minnesota · New York · South Carolina · Tennessee · Texas
NCT07533175 on ClinicalTrials.gov ↗
Active
Abbott Medical - VERITAS Study
Atrial Fibrillation (AF), Stoke
Abbott Medical Devices · started 2024-11-07
📍 Arizona · Arkansas · Florida · Georgia · Kansas · Michigan · Minnesota · Nebraska
NCT06707688 on ClinicalTrials.gov ↗
Active Phase 3
A Research Study to Look at How Semaglutide Compared to Placebo Affects Diabetic Eye Disease in People With Type 2 Diabetes
Diabetes Mellitus, Type 2
Novo Nordisk A/S · started 2019-05-08
📍 Arizona · California · Colorado · Connecticut · Florida · Georgia · Illinois · Indiana
NCT03811561 on ClinicalTrials.gov ↗
Recruiting Phase 2
A Study to Assess Adverse Events and Change in Disease Activity of Multiple Treatment Combinations With Intravenous Mirvetuximab Soravtansine in Adult Participants With Ovarian Cancer
Ovarian Cancer
AbbVie · started 2025-11-13
📍 California · Florida · Kentucky · Louisiana · Maine · Michigan · Montana · New Jersey
NCT07059845 on ClinicalTrials.gov ↗
Recruiting Phase 2/Phase 3
(HARBOR) Study to Evaluate Efficacy and Safety of BLU-263 Versus Placebo in Patients With Indolent Systemic Mastocytosis
Indolent Systemic Mastocytosis, Smoldering Systemic Mastocytosis
Blueprint Medicines Corporation · started 2021-11-30
📍 Alabama · California · Colorado · Georgia · Massachusetts · Michigan · Minnesota · New York
NCT04910685 on ClinicalTrials.gov ↗
Active Phase 2
A Study of Barzolvolimab in Patients With Prurigo Nodularis
Prurigo Nodularis
Celldex Therapeutics · started 2024-04-12
📍 Alabama · Arizona · California · Florida · Georgia · Idaho · Illinois · Indiana
NCT06366750 on ClinicalTrials.gov ↗
Recruiting
Safety and Effectiveness of Left Bundle Branch Area Pacing Versus Conventional Cardiac Resynchronization Therapy in Heart Failure
Heart Failure - NYHA II - IV
Boston Scientific Corporation · started 2025-10-22
📍 Alabama · Arizona · Arkansas · California · District of Columbia · Florida · Georgia · Illinois
NCT07069738 on ClinicalTrials.gov ↗
By invitation Phase 3
A Long-Term Extension Study to Learn More About the Safety of Litifilimab (BIIB059) Injections and Whether They Can Improve Symptoms of Adult Participants Who Have Active Cutaneous Lupus Erythematosus
Subacute Cutaneous Lupus Erythematosus, Chronic Cutaneous Lupus Erythematosus
Biogen · started 2023-10-03
📍 Alabama · Arizona · California · Michigan · Missouri · North Carolina · Ohio · Pennsylvania
NCT06044337 on ClinicalTrials.gov ↗
Recruiting
Multi-site Study of the Clinical Impact of an AI-assisted Approach to Referring Patients With Interstitial Lung Disease for Diagnostic Evaluation of Pulmonary Hypertension
Pulmonary Hypertension, Interstitial Lung Disease (ILD)
Tempus AI · started 2025-07-23
📍 Alabama · Arizona · Colorado · Florida · Illinois · Indiana · Kentucky · Louisiana
NCT06911632 on ClinicalTrials.gov ↗
Starting soon
A Study Comparing ETHICON™ 4000 Stapler System With Standard of Care Stapling Devices in Adults Undergoing Gastric and Thoracic Procedures
Surgical Procedures, Operative
Ethicon Endo-Surgery · started 2026-09-16
📍 California · Indiana · Michigan · Missouri · Pennsylvania
NCT07744568 on ClinicalTrials.gov ↗
Recruiting Phase 1
A Trial to Evaluate Ovarian Suppression Following Subcutaneous ZOLADEX 10.8 mg in Premenopausal Women With HR+, HER2- Advanced Breast Cancer
Advanced Breast Cancer
TerSera Therapeutics LLC · started 2026-08-30
📍 Arkansas · District of Columbia · Florida · Georgia · Illinois · Michigan · Montana · New Mexico
NCT07310420 on ClinicalTrials.gov ↗
Recruiting
An Observational Study in Participants With Indolent Systemic Mastocytosis (ISM)
Indolent Systemic Mastocytosis
Blueprint Medicines Corporation · started 2026-04-15
📍 Maryland · Massachusetts · Michigan
NCT07264959 on ClinicalTrials.gov ↗
Recruiting Phase 2
Illuminate: A Clinical Study Evaluating CAR T Immune Cell Therapy (BCB-276) for Patients With Diffuse Intrinsic Pontine Glioma (DIPG).
Diffuse Intrinsic Pontine Glioma, DIPG, Brain Tumor, CNS Tumor
BrainChild Bio, Inc · started 2026-08
📍 California · Georgia · Illinois · Ohio · Pennsylvania · Washington
NCT07680439 on ClinicalTrials.gov ↗
Active Phase 2
A Study to Evaluate the Effectiveness and Safety of Treatments, Either Alone or in Combination, for the Treatment of Moderate to Severe Atopic Dermatitis
Atopic Dermatitis
AbbVie · started 2024-12-19
📍 Arizona · California · Colorado · Florida · Illinois · Nebraska · New York · Oregon
NCT06718101 on ClinicalTrials.gov ↗
Starting soon Phase 3
A Research Study to Compare Two Different Versions of Injectable Cagrilintide and Placebo in People With Excess Body Weight
Overweight, Obesity
Novo Nordisk A/S · started 2026-08-04
📍 Georgia · Hawaii · Illinois · Indiana · Kentucky · North Carolina · South Carolina · Virginia
NCT07745504 on ClinicalTrials.gov ↗
Active Phase 3
Trial to Evaluate Acasunlimab and Pembrolizumab Combination Superiority Over Standard of Care Docetaxel in Non-Small Cell Lung Cancer (ABBIL1TY NSCLC-06)
PD-L1-positive, Locally Advanced (Unresectable Stage IIIB/C) or Metastatic NSCLC
Genmab · started 2024-11-25
📍 Arizona · California · Florida · Georgia · Hawaii · Illinois · Indiana · Kentucky
NCT06635824 on ClinicalTrials.gov ↗
Active
CHAMPION-AF Clinical Trial
Atrial Fibrillation, Stroke, Bleeding
Boston Scientific Corporation · started 2020-10-15
📍 Alabama · Arizona · Arkansas · California · Colorado · Connecticut · Delaware · District of Columbia
NCT04394546 on ClinicalTrials.gov ↗
Active Phase 1/Phase 2
GEN1042 Safety Trial and Anti-tumor Activity in Participants With Malignant Solid Tumors
Malignant Solid Tumor, Non-Small Cell Lung Cancer (NSCLC), Colorectal Cancer (CRC), Melanoma
Genmab · started 2019-09-17
📍 Alaska · California · Connecticut · Delaware · Florida · Illinois · Kentucky · Maryland
NCT04083599 on ClinicalTrials.gov ↗
Recruiting Phase 1
A Study in Patients With Metastatic Castration-Resistant Prostate Cancer
Metastatic Castration Resistant Prostate Cancer, mCRPC, mCRPC (Metastatic Castration-resistant Prostate Cancer), Prostatic Neoplasms
Flare Therapeutics Inc. · started 2026-07-01
📍 California · Massachusetts · Michigan · New Jersey · South Carolina · Tennessee · Texas · Virginia
NCT07719361 on ClinicalTrials.gov ↗
Active Phase 1
DAREON™-7: A Study to Test How Well Different Doses of BI 764532 in Addition to Chemotherapy Are Tolerated by People With Advanced Neuroendocrine Cancers
Neuroendocrine Neoplasms
Boehringer Ingelheim · started 2024-01-22
📍 Florida · Georgia · Illinois · New Jersey · Pennsylvania
NCT06132113 on ClinicalTrials.gov ↗
Recruiting Phase 2
Study of LHP588 in Subjects With P. Gingivalis-Positive Alzheimer's Disease
Alzheimer Disease, Alzheimer Disease Due to P. Gingivalis
Lighthouse Pharmaceuticals, Inc. · started 2025-02-17
📍 Arizona · California · Colorado · Florida · Georgia · Kansas · Louisiana · Maryland
NCT06847321 on ClinicalTrials.gov ↗
Active Phase 1/Phase 2
Safety and Efficacy Trial of Epcoritamab Combinations in Subjects With B-cell Non-Hodgkin Lymphoma (B-NHL)
Diffuse Large B-Cell Lymphoma, Follicular Lymphoma
Genmab · started 2020-11-03
📍 Alabama · California · Massachusetts · Michigan · New Jersey · New York · North Carolina · Texas
NCT04663347 on ClinicalTrials.gov ↗
Active Phase 2
Clairleafᵀᴹ: A Study to Test Long-term Treatment With BI 1291583 in People With Bronchiectasis Who Took Part in a Previous Study With This Medicine
Bronchiectasis
Boehringer Ingelheim · started 2023-09-08
📍 California · Florida · Kansas · New York · Ohio · South Carolina · Texas
NCT05846230 on ClinicalTrials.gov ↗
Recruiting Phase 3
COMO: A Phase 3 Randomized, Double-Masked Study Comparing the Efficacy of EYP-1901 Against Aflibercept in DME
Diabetic Macular Edema, DME, Diabetic Macular Edema (DME)
EyePoint Pharmaceuticals, Inc. · started 2026-02-16
📍 California · Colorado · Florida · Georgia · Hawaii · Illinois · Indiana · Louisiana
NCT07449936 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Study to Evaluate the Safety and Efficacy of Oral Nizubaglustat (AZ-3102) in Late-infantile and Juvenile Forms of Niemann-Pick Type C Disease, GM1 Gangliosidosis or GM2 Gangliosidosis
Niemann-Pick Type C Disease, GM1 Gangliosidosis, GM2 Gangliosidosis
Azafaros B.V. · started 2025-06-30
📍 California · Minnesota · Texas · Virginia
NCT07054515 on ClinicalTrials.gov ↗
Recruiting Phase 3
Extension Trial to Evaluate the Long-term Efficacy, Safety, and Tolerability of Maridebart Cafraglutide (MARITIME-1-EXTENSION)
Obesity, Overweight
Amgen · started 2026-07-23
📍 Alabama · California · Connecticut · Florida · Illinois · Louisiana · Michigan · New York
NCT07684235 on ClinicalTrials.gov ↗
Recruiting Phase 2
A Phase 2 Study of VS-7375 in Patients With KRAS G12D-Mutated Pancreatic Cancer
Pancreatic Ductal Adenocarcinoma (PDAC), G12D Mutated KRAS
Verastem, Inc. · started 2026-06-16
📍 California · Florida · Maryland · Massachusetts · Michigan · Missouri · New Jersey · New York
NCT07644559 on ClinicalTrials.gov ↗
Starting soon
Evaluation of Male and Female External Catheters for Urine Output Monitoring in the ICU
Urine Output, ICU Patients
C. R. Bard · started 2026-08
📍 Utah
NCT07744945 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Phase III Study to Investigate the Efficacy and Safety of Elecoglipron Compared With Placebo in Adults With Type 2 Diabetes Mellitus on Background Insulin
Type 2 Diabetes Mellitus
AstraZeneca · started 2026-07-08
📍 Arkansas · California · Colorado · Florida · Georgia · Maryland · New York · North Carolina
NCT07664553 on ClinicalTrials.gov ↗
Active Phase 1
Study to Assess Adverse Events and Change in Disease Activity in Adult Participants With Select Advanced Solid Tumor Indications Receiving Intravenous (IV) ABBV-400
Hepatocellular Carcinoma, Pancreatic Ductal Adenocarcinoma, Biliary Tract Cancers, Esophageal Squamous Cell Carcinoma
AbbVie · started 2023-11-09
📍 California · Colorado · Florida · Illinois · Michigan · Missouri · New York · North Carolina
NCT06084481 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Phase III Study to Investigate the Efficacy and Safety of Elecoglipron Alone or in Combination With Dapagliflozin Compared With Placebo in Adults With Type 2 Diabetes Mellitus
Type 2 Diabetes Mellitus
AstraZeneca · started 2026-07-06
📍 Alabama · California · Colorado · Connecticut · Florida · Georgia · Kansas · Kentucky
NCT07662044 on ClinicalTrials.gov ↗
Starting soon
This is a Randomized, Open-label, 4-arm Pilot Study Designed to Evaluate the Efficacy and Tolerability of Four Qualia Sleep Formulations (Formulas A, B, C, and D) in Healthy Adults Aged 18 Years and Older Who Report Poor Sleep Quality. The Investigational Products Are Encapsulated Dietary Supplement
Sleep Quality
Qualia Life Sciences · started 2026-08-28
📍 California
NCT07744971 on ClinicalTrials.gov ↗
Active Phase 3
A 2-year Study of EYP-1901 in Subjects With Wet Age Related Macular Degeneration (wAMD) (LUCIA) Primary Efficacy Will be Determined at Week 56
Wet Age Related Macular Degeneration, wAMD
EyePoint Pharmaceuticals, Inc. · started 2024-11-27
📍 Arizona · California · Colorado · Connecticut · Florida · Illinois · Indiana · Kentucky
NCT06683742 on ClinicalTrials.gov ↗
Recruiting Phase 2/Phase 3
A Study to Assess Adverse Events and Change in Disease Activity When Intravenous (IV) Pivekimab Sunirine is Given in Combination With Oral Venetoclax and IV or Subcutaneous Azacitidine in Adult Participants With Acute Myeloid Leukemia (AML)
Acute Myeloid Leukemia
AbbVie · started 2026-06-30
📍 Arizona · California · Florida · New York
NCT07581002 on ClinicalTrials.gov ↗
Recruiting Phase 3
Phase 3 Trial Evaluating the Safety & Efficacy of IMNN-001 Administered in Combination w/ Standard NACT & Adjuvant Chemotherapy in Newly Diagnosed Patients w/ Advanced EOC, Fallopian Tube or Primary Peritoneal Cancer
Epithelial Ovarian Cancer, Ovarian Cancer, Fallopian Tube Cancer, Primary Peritoneal Carcinoma
Imunon · started 2025-07-09
📍 Florida · Minnesota · Missouri · Oregon · South Dakota · Tennessee · Washington · Wisconsin
NCT06915025 on ClinicalTrials.gov ↗
Recruiting Phase 3
AMAZE 4: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Obstructive Sleep Apnoea Treated With Positive Airway Pressure Lose Weight and Improve Sleep Apnoea
Obesity, Overweight, Obstructive Sleep Apnoea
Novo Nordisk A/S · started 2026-05-05
📍 Arizona · Florida · Georgia · Illinois · New York · North Dakota · Ohio · Pennsylvania
NCT07571109 on ClinicalTrials.gov ↗
Active Phase 1/Phase 2
First-in-Human (FIH) Trial in Patients With Relapsed, Progressive or Refractory B-Cell Lymphoma
DLBCL, High-grade B-cell Lymphoma (HGBCL), Primary Mediastinal Large B-cell Lymphoma (PMBCL), FL
Genmab · started 2018-06-26
📍 Arizona · California · Colorado · Florida · Iowa · Louisiana · Michigan · Nebraska
NCT03625037 on ClinicalTrials.gov ↗
Active Phase 1/Phase 2
A Study of Novel Anti-cancer Agents in Patients With Metastatic Triple Negative Breast Cancer
Triple Negative Breast Neoplasms
AstraZeneca · started 2018-12-21
📍 Arizona · Maryland · Massachusetts · Michigan · Missouri · Texas · Virginia
NCT03742102 on ClinicalTrials.gov ↗
Recruiting
The Ailliance Post-Market Clinical Study
Spinal Deformity, Spinal Degenerative Disorder, Spinal Fusion Failure, Spinal Trauma
Medtronic Spinal and Biologics · started 2023-05-01
📍 Arizona · Arkansas · California · Indiana · Kentucky · Maryland · Michigan · Minnesota
NCT05856370 on ClinicalTrials.gov ↗
Recruiting Phase 3
Study to Assess the Efficacy and Safety of Rina-S Compared to Treatment of Investigator's Choice in Participants With Endometrial Cancer
Endometrial Cancer, Recurrent or Progressive Endometrial Cancer
Genmab · started 2025-11-28
📍 Alabama · Arizona · California · Connecticut · District of Columbia · Florida · Georgia · Louisiana
NCT07166094 on ClinicalTrials.gov ↗
Recruiting Phase 3
Study to Assess the Efficacy and Safety of Rina-S Plus Standard of Care Compared to Standard of Care for Maintenance Treatment of Participants With Recurrent Platinum-sensitive Ovarian Cancer After Second-line (2L) Platinum-based Doublet Chemotherapy
Ovarian Cancer, Platinum-sensitive Ovarian Cancer, PSOC
Genmab · started 2026-04-03
📍 Florida · Ohio
NCT07225270 on ClinicalTrials.gov ↗
Recruiting Phase 1/Phase 2
Evaluate the Safety, Tolerability, and Preliminary Efficacy of EVM14 Alone and in Combination in Patients With Selected Solid Tumors
Selected Types of Solid Tumor
Everest Medicines (Beijing) Co., Ltd. · started 2025-11-17
📍 New York · Texas · Virginia
NCT07095868 on ClinicalTrials.gov ↗
Starting soon Phase 2
A Study to Assess Adverse Events, Change in Disease Activity and Optimal Dose of Intravenous (IV) Telisotuzumab Adizutecan With IV Pembrolizumab for First-Line Treatment of Adult Participants With Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma
Head and Neck Squamous Cell Carcinoma
AbbVie · started 2026-09-30
📍 Arkansas · Georgia · Illinois · Oklahoma · Texas · Virginia
NCT07744126 on ClinicalTrials.gov ↗
Active Phase 3
Study of Subcutaneous Epcoritamab in Combination With Intravenous Rituximab and Oral Lenalidomide (R2) to Assess Adverse Events and Change in Disease Activity in Adult Participants With Previously Untreated Follicular Lymphoma
Follicular Lymphoma (FL)
Genmab · started 2024-02-05
📍 California · Colorado · Delaware · Florida · Idaho · Illinois · Indiana · Iowa
NCT06191744 on ClinicalTrials.gov ↗
Active Phase 1
Study to Evaluate Adverse Events, Change in Disease Activity, and How Oral ABBV-101 Moves Through the Body in Adult Participants With B-Cell Malignancies
Hematologic Cancer
AbbVie · started 2023-06-09
📍 Arizona · California · Colorado · Illinois · Massachusetts · New Jersey · New York · Ohio
NCT05753501 on ClinicalTrials.gov ↗
Recruiting Phase 1
A Phase 1 Trial of AMG 691 in Healthy Chinese and Japanese Volunteers
Healthy Participants
Amgen · started 2026-08-07
📍 Nevada
NCT07745907 on ClinicalTrials.gov ↗
Recruiting Phase 2
Study to Assess the Efficacy and Safety of Rina-S in Participants With Non-small Cell Lung Cancer
Non-small Cell Lung Cancer (NSCLC)
Genmab · started 2026-01-30
📍 California · District of Columbia · Florida · Georgia · Montana · Nebraska · New Jersey · New York
NCT07288177 on ClinicalTrials.gov ↗
Recruiting Phase 2
A Study to Evaluate the Efficacy, Safety, and Tolerability of VIM0423 in Individuals With Isolated Dystonia
Dystonia
Vima Therapeutics · started 2026-02-05
📍 Alabama · Arizona · California · Colorado · Florida · Georgia · Illinois · Kansas
NCT07304089 on ClinicalTrials.gov ↗
Recruiting Phase 3
ATSN-201 Gene Therapy in RS1-Associated X-linked Retinoschisis
X-linked Retinoschisis
Atsena Therapeutics Inc. · started 2023-08-22
📍 Arizona · California · Florida · Massachusetts · Michigan · Minnesota · New York · North Carolina
NCT05878860 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Phase 3 Study of Rezpegaldesleukin (NKTR-358) for Patients ≥ 12 Years of Age With Moderate-to-Severe Atopic Dermatitis
Moderate-to-Severe Atopic Dermatitis
Nektar Therapeutics · started 2026-06-29
📍 California · Florida · Georgia · Illinois · Kentucky · Louisiana · Nebraska · New Jersey
NCT07690371 on ClinicalTrials.gov ↗
Recruiting Phase 2
A Study to Evaluate the Adverse Events, and Efficacy of Intravenous (IV) of Telisotuzumab Adizutecan in Combination With IV Oxaliplatin, Fluorouracil, Folinic Acid/Leucovorin, Bevacizumab, Panitumumab in Adult Participants With Metastatic Colorectal Cancer
Metastatic Colorectal Cancer
AbbVie · started 2025-04-24
📍 California · Connecticut · Georgia · Illinois · Massachusetts · Michigan · Missouri · Nebraska
NCT06820463 on ClinicalTrials.gov ↗
Active Phase 1
A Study to Test Different Doses of BI 1701963 Alone and Combined With Trametinib in Patients With Different Types of Advanced Cancer (Solid Tumours With KRAS Mutation)
Solid Tumors, KRAS Mutation; SOS1
Boehringer Ingelheim · started 2019-11-04
📍 Massachusetts · North Carolina · Tennessee · Texas
NCT04111458 on ClinicalTrials.gov ↗
Active Phase 1
A Study to Test BI 765179 Alone and in Combination With Ezabenlimab in Patients With Advanced Cancer (Solid Tumors) and BI 765179 in Combination With Pembrolizumab in Patients With Advanced Head and Neck Cancer
Neoplasms
Boehringer Ingelheim · started 2021-10-18
📍 Arizona · California · North Carolina · South Dakota · Texas
NCT04958239 on ClinicalTrials.gov ↗
Active Phase 3
Study of Elafibranor in Patients With Primary Biliary Cholangitis (PBC)
Primary Biliary Cirrhosis
Ipsen · started 2020-09-24
📍 Arizona · California · Colorado · Connecticut · Florida · Georgia · Kansas · Massachusetts
NCT04526665 on ClinicalTrials.gov ↗
Recruiting Phase 1/Phase 2
Rinatabart Sesutecan (Rina-S, PRO1184, GEN1184) for Advanced Solid Tumors (GCT1184-01/ PRO1184-001)
High Grade Epithelial Ovarian Cancer, High Grade Serous Ovarian Cancer, Primary Peritoneal Carcinoma, Fallopian Tube Cancer
Genmab · started 2022-12-07
📍 Arizona · California · Florida · Georgia · Kansas · Maryland · Massachusetts · Michigan
NCT05579366 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Study to Investigate Ronde-cel Versus Investigator's Choice CD19 CAR T-Cell Therapy
Large B-cell Lymphoma, Lymphoma, B-Cell, Relapsed Non-Hodgkin Lymphoma, Refractory Non-Hodgkin Lymphoma
Lyell Immunopharma, Inc. · started 2026-01-12
📍 Arizona · Arkansas · California · Colorado · District of Columbia · Florida · Georgia · Illinois
NCT07188558 on ClinicalTrials.gov ↗
Active Phase 3
A Clinical Trial for Participants With DEE to Assess Efficacy, Safety, Tolerability, and PK of Relutrigine
Developmental and Epileptic Encephalopathy 1
Praxis Precision Medicines · started 2025-07-09
📍 California · Florida · Maryland · Minnesota · New Jersey · Pennsylvania
NCT07010471 on ClinicalTrials.gov ↗
Recruiting Phase 2/Phase 3
A Study to Assess Intravenous (IV) Telisotuzumab Adizutecan in Combination With Fluorouracil, Folinic Acid, and Oxaliplatin (FOLFOX) Compared to Standard of Care in Adult Participants With First-Line Metastatic Pancreatic Ductal Adenocarcinoma
Metastatic Pancreatic Ductal Adenocarcinoma, PDAC
AbbVie · started 2026-04-30
📍 Illinois · Michigan · Texas · Virginia
NCT07490301 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Study of Ifinatamab Deruxtecan in Subjects With Pretreated Advanced or Metastatic Esophageal Squamous Cell Carcinoma (ESCC) (IDeate-Esophageal01)
Esophageal Squamous Cell Carcinoma
Daiichi Sankyo · started 2025-03-27
📍 Arizona · California · Michigan · Minnesota · Missouri · New Jersey · New York · Pennsylvania
NCT06644781 on ClinicalTrials.gov ↗
Active Phase 1/Phase 2
Safety and Efficacy Study of Epcoritamab in Subjects With Relapsed/Refractory Chronic Lymphocytic Leukemia and Richter's Syndrome
Relapsed/Refractory Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma, Richter's Syndrome, Treatment-naïve High Risk Chronic Lymphocytic Leukemia
Genmab · started 2020-11-25
📍 Alabama · California · Florida · Maryland · Massachusetts · Michigan · New Jersey · New York
NCT04623541 on ClinicalTrials.gov ↗
Active Phase 3
A Global Study to Assess the Effects of Osimertinib Following Chemoradiation in Patients With Stage III Unresectable Non-small Cell Lung Cancer (LAURA)
Non Small Cell Lung Cancer (Stage III)
AstraZeneca · started 2018-07-19
📍 California · Georgia · New Jersey · Utah · Wisconsin
NCT03521154 on ClinicalTrials.gov ↗
Recruiting Phase 2
A Study of the Efficacy and Safety of Adjuvant Autogene Cevumeran Plus Atezolizumab and mFOLFIRINOX Versus mFOLFIRINOX Alone in Participants With Resected PDAC
Adenocarcinoma, Pancreatic Ductal
Genentech, Inc. · started 2023-10-18
📍 California · Connecticut · Illinois · Indiana · Kentucky · Massachusetts · Michigan · Nebraska
NCT05968326 on ClinicalTrials.gov ↗
Recruiting Phase 1
A Study to Test the Safety and Effects of Inhaled GDC-6988 in Participants With Muco-obstructive Disease
Non-cystic Fibrosis Bronchiectasis, Chronic Obstructive Pulmonary Disease
Genentech, Inc. · started 2024-11-18
📍 Alabama · California · Kansas · North Carolina · Pennsylvania · Texas
NCT06603246 on ClinicalTrials.gov ↗
Recruiting
The SetPoint System as a Pro-Remyelination Therapy for Relapsing-Remitting Multiple Sclerosis: A Pilot Study
Relapsing Remitting Multiple Sclerosis
SetPoint Medical Corporation · started 2026-04-17
📍 California · Georgia · Maryland · Minnesota · Texas · Washington · West Virginia · Wisconsin
NCT06796504 on ClinicalTrials.gov ↗
Recruiting Phase 1
A Study to Test How Different Doses of BI 1703880 in Combination With Ezabenlimab Are Tolerated in People With Different Types of Advanced Cancer (Solid Tumours)
Solid Tumors
Boehringer Ingelheim · started 2023-02-24
📍 California · Connecticut · New Jersey
NCT05471856 on ClinicalTrials.gov ↗
Recruiting
ReneuRx™ (Nerve Selective Therapy) Utilized in Lateral Hip Pain
Greater Trochanteric Pain Syndrome, Greater Trochanteric Pain Syndrome of Both Lower Limbs, Lateral Hip Pain
Brixton Biosciences, Inc. · started 2026-07-27
📍 Arizona · Georgia · Louisiana · Massachusetts · New Jersey · Oklahoma · Pennsylvania · Texas
NCT07568015 on ClinicalTrials.gov ↗
Recruiting Phase 3
Study of Oral Upadacitinib and Subcutaneous/Intravenous Tocilizumab to Evaluate Change in Disease Activity, Adverse Events and How Drug Moves Through the Body of Pediatric and Adolescent Participants With Active Systemic Juvenile Idiopathic Arthritis.
Juvenile Idiopathic Arthritis
AbbVie · started 2023-10-02
📍 Arizona · District of Columbia · New York · North Carolina · Ohio · Oregon
NCT05609630 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Phase III Study to Investigate the Efficacy and Safety of Elecoglipron Compared With Placebo in Adults With Type 2 Diabetes Mellitus and Impaired Renal Function on Background Dapagliflozin
Type 2 Diabetes Mellitus, Type 2 Diabetes With Chronic Kidney Disease
AstraZeneca · started 2026-07-06
📍 Arizona · California · Florida · Illinois · Massachusetts · Michigan · Minnesota · Missouri
NCT07662135 on ClinicalTrials.gov ↗
By invitation
Shortwave Infrared Surgical Imaging Device Study
Cholecystitis, Cholecystitis, Chronic, Chronic Calculous Cholecystitis, Primary Hyperparathyroidism
Cision Vision, Inc. · started 2026-05-29
📍 California · Illinois · Maryland
NCT07744425 on ClinicalTrials.gov ↗
Active Phase 3
Research Study on Whether Semaglutide Works in People With Non-alcoholic Steatohepatitis (NASH)
Non-alcoholic Steatohepatitis
Novo Nordisk A/S · started 2021-04-01
📍 Alabama · Arizona · Arkansas · California · Colorado · Connecticut · Florida · Georgia
NCT04822181 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Study Comparing TAK-928 With Docetaxel in Adults With Non-Small Cell Lung Cancer
IO-resistant sqNSCLC
Takeda · started 2025-11-26
📍 Arkansas · California · Florida · Texas
NCT07217301 on ClinicalTrials.gov ↗
Active Phase 3
A 2-year Study of EYP-1901 in Subjects With Wet Age Related Macular Degeneration (wAMD) (LUGANO) Primary Efficacy Will be Determined at Week 56
Wet Age Related Macular Degeneration, wAMD
EyePoint Pharmaceuticals, Inc. · started 2024-10-22
📍 Arizona · Arkansas · California · Colorado · Connecticut · Florida · Georgia · Hawaii
NCT06668064 on ClinicalTrials.gov ↗
Recruiting Phase 1
A Study of LTX-001 In Adult Participants With Acute Exacerbation of Schizophrenia
Schizophrenia
Leal Therapeutics, Inc · started 2026-08
📍 Arkansas · California · Florida · Georgia · Maryland · New Jersey · Texas
NCT07734493 on ClinicalTrials.gov ↗
Recruiting Phase 2
A Phase 2 Study to Evaluate the Safety, PD, PK, and Clinical Activity of ADX-097 in Participants With IgAN, LN or C3G
IgA Nephropathy, Lupus Nephritis (LN), C3 (Complement Component 3) Glomerulopathy
Akebia Therapeutics · started 2026-07-30
📍 Georgia
NCT06419205 on ClinicalTrials.gov ↗
Recruiting Phase 1
Phase I Trial to Determine the Dose and Evaluate the PK and Safety of Lutetium Lu 177 Edotreotide Therapy in Pediatric Participants With SSTR-positive Tumors
Somatostatin Receptor Positive, NETs, Lymphoma, Solid Tumor
ITM Solucin GmbH · started 2025-09-26
📍 California · Pennsylvania · Texas
NCT06441331 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Study to Investigate the Efficacy and Safety of Apraglutide Compared With Placebo in Adult Participants With Short Bowel Syndrome Associated With Intestinal Failure (SBS-IF)
Short Bowel Syndrome (SBS), SBS Associated With Intestinal Failure (SBS-IF)
VectivBio AG · started 2026-08
📍 California · Colorado · District of Columbia · Florida · Illinois · Kentucky · Michigan · New York
NCT07742735 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Study to Assess the Efficacy and Safety of Induction Therapy With Afimkibart (RO7790121) in Participants With Moderately to Severely Active Crohn's Disease
Moderately to Severely Active Crohns Disease
Hoffmann-La Roche · started 2025-05-12
📍 Alabama · Arizona · California · Colorado · Florida · Georgia · Illinois · Kansas
NCT06819891 on ClinicalTrials.gov ↗
Recruiting Phase 3
Reducing Adverse Vascular Outcomes With Factor XI Inhibition in Adult Participants With Peripheral Artery Disease
Peripheral Artery Disease (PAD)
Regeneron Pharmaceuticals · started 2026-07-10
📍 Alabama · Arizona · Arkansas · Florida · Indiana · Louisiana · North Carolina · Tennessee
NCT07318610 on ClinicalTrials.gov ↗
Recruiting
Outcomes of Physiologic Insulin Resensitization (PIR) in Patients With Chronic Kidney Disease and Type 2 Diabetes Mellitus
Chronic Kidney Disease (Stages 4 and 5), Kidney Disease, Type 2 Diabetes
Well Cell Global · started 2025-10-14
📍 Arizona
NCT07187479 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Phase III Study to Investigate the Efficacy and Safety of the Combination of Elecoglipron and Dapagliflozin in Adults With Type 2 Diabetes Mellitus
Type 2 Diabetes Mellitus
AstraZeneca · started 2026-07-06
📍 Alabama · Arkansas · California · Florida · Georgia · Illinois · Indiana · Iowa
NCT07662109 on ClinicalTrials.gov ↗
Active
LUX-Dx TRENDS Evaluates Diagnostics Sensors in Heart Failure Patients Receiving Boston Scientific's Investigational ICM System.
Heart Failure
Boston Scientific Corporation · started 2021-03-20
📍 Alabama · Arkansas · California · Florida · Georgia · Idaho · Illinois · Indiana
NCT04790344 on ClinicalTrials.gov ↗
Recruiting Phase 1
Phase 1 Study of ACE-232 to Treat Patients With Metastatic Castration-Resistant Prostate Cancer
Prostate Cancer (Adenocarcinoma), mCRPC (Metastatic Castration-resistant Prostate Cancer)
Acerand Therapeutics (Hong Kong) Limited · started 2025-05-12
📍 California · Florida · Maryland · Massachusetts · Minnesota · Nebraska · South Carolina · Washington
NCT06801236 on ClinicalTrials.gov ↗
Recruiting Phase 2
A Study to Evaluate the Efficacy and Safety of Autogene Cevumeran With Nivolumab Versus Nivolumab Alone in Participants With High-risk Muscle-invasive Urothelial Carcinoma (MIUC)
Muscle-invasive Urothelial Carcinoma
Hoffmann-La Roche · started 2024-12-09
📍 Arkansas · California · Connecticut · District of Columbia · Kentucky · Michigan · New Jersey · New York
NCT06534983 on ClinicalTrials.gov ↗
Active Phase 2
A Study of Weekly Oral Dose of Ecnoglutide (VRB-101) for Weight Maintenance in Participants Who Have Obesity or Overweight With Weight-Related Comorbidities
Obesity, Overweight, Weight Maintenance
Verdiva Bio Dev Limited · started 2026-06-12
📍 Alabama · Arizona · Arkansas · California · Connecticut · Florida · Illinois · Kansas
NCT07553299 on ClinicalTrials.gov ↗
Active Phase 2
Phase IIa Study Evaluating AZD7798 in Crohn's Disease
Moderate to Severe Crohn's Disease
AstraZeneca · started 2024-08-28
📍 Arizona · California · Connecticut · Florida · Idaho · Kansas · Michigan · Missouri
NCT06450197 on ClinicalTrials.gov ↗
Active Phase 2
A Study of Eltrekibart (LY3041658) in Adult Participants With Moderate to Severe Hidradenitis Suppurativa
Hidradenitis Suppurativa
Eli Lilly and Company · started 2023-10-23
📍 Arizona · Arkansas · California · Connecticut · Florida · Georgia · Illinois · Indiana
NCT06046729 on ClinicalTrials.gov ↗
Recruiting Phase 3
Acoramidis Transthyretin Amyloidosis Prevention Trial in the Young (ACT-EARLY) Study in Asymptomatic Carriers of a Pathogenic TTR Variant
Amyloidosis, Amyloid Cardiomyopathy, Transthyretin Amyloidosis, Cardiomyopathies
Eidos Therapeutics, a BridgeBio company · started 2025-05-12
📍 California · Colorado · Connecticut · District of Columbia · Florida · Georgia · Illinois · Maryland
NCT06563895 on ClinicalTrials.gov ↗
Recruiting Phase 3
Phase III Study of Ivonescimab or Bevacizumab Combined With FOLFOX in Patients With Metastatic Colorectal Cancer
Metastatic Colorectal Cancer (CRC)
Summit Therapeutics · started 2025-11-18
📍 Alabama · Arizona · California · Connecticut · Delaware · Florida · Georgia · Illinois
NCT07228832 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Study of Orelabrutinib in Patients With Primary Progressive Multiple Sclerosis
Multiple Sclerosis (MS) Primary Progressive
Zenas BioPharma (USA), LLC · started 2026-03-23
📍 Arizona · California · Florida · Kansas · Missouri · New Jersey · North Carolina · Ohio
NCT07067463 on ClinicalTrials.gov ↗
Recruiting
Safety and Performance of the OTTAVA System in Participants Undergoing Inguinal Hernia Repair
Hernia, Inguinal
Auris Health, Inc. · started 2026-03-11
📍 Florida · Indiana · North Carolina · Texas
NCT07298317 on ClinicalTrials.gov ↗
Recruiting Phase 3
Carcinoid Syndrome Efficacy Study Featuring an Oral Daily Paltusotine Regimen
Carcinoid Syndrome, Carcinoid, Carcinoid Tumor, Carcinoid Tumor of Ileum
Crinetics Pharmaceuticals Inc. · started 2025-11-19
📍 Arizona · California · Connecticut · Florida · Georgia · Iowa · Kentucky · Louisiana
NCT07087054 on ClinicalTrials.gov ↗
Recruiting Phase 1
A Phase I Study to Investigate the Effect of Hepatic Impairment of AZD9550 and AZD6234
Hepatic Impairment
AstraZeneca · started 2026-03-20
📍 Arizona · California · Florida · Texas
NCT07546760 on ClinicalTrials.gov ↗
Recruiting Phase 2
Study of Oral MRT-2359 With Apalutamide in Prostate Cancer
Castration-Resistant Prostate Cancer (CRPC), Castration-Resistant Prostate Cancer, Prostate Cancer, Prostate Cancer (Adenocarcinoma)
Monte Rosa Therapeutics, Inc · started 2026-08
📍 California · Colorado · Kansas · Maryland · Michigan · Nebraska · New Jersey · North Carolina
NCT07745361 on ClinicalTrials.gov ↗
Recruiting Phase 1/Phase 2
A Study of Ifinatamab Deruxtecan in Pediatric Participants With Relapsed or Refractory Solid Tumors (MK-9999-01D/LIGHTBEAM-U01)
Malignant Neoplasm
Merck Sharp & Dohme LLC · started 2026-07-02
📍 Iowa · Massachusetts · New Jersey · New York · Pennsylvania · Utah
NCT07630974 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Study to Investigate the Effect of Mitapivat on Transfusion Burden in Subjects With Sickle Cell Disease (SCD)
Sickle Cell Disease
Agios Pharmaceuticals, Inc. · started 2026-07-21
📍 Indiana · Michigan · Mississippi
NCT07656415 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Study to Evaluate the Safety and Efficacy of Oral Nizubaglustat (AZ-3102) in Late-infantile and Juvenile Forms of Niemann-Pick Type C Disease (NPC)
Niemann-Pick Type C Disease
Azafaros B.V. · started 2025-06-30
📍 California · Minnesota · Texas · Virginia
NCT07082725 on ClinicalTrials.gov ↗
Starting soon
WATER IV PCa (AS Sub-study)
Localized Prostate Cancer
PROCEPT BioRobotics · started 2026-09
📍 Arizona · California · Colorado · Florida · Georgia · Idaho · Illinois · Maryland
NCT07650448 on ClinicalTrials.gov ↗
Recruiting
Deep Brain Stimulation (DBS) Retrospective Outcomes Study
Parkinson Disease, Essential Tremor, Dystonia
Boston Scientific Corporation · started 2019-03-12
📍 Arizona · California · Florida · Idaho · New York · North Carolina · Pennsylvania · Washington
NCT03664609 on ClinicalTrials.gov ↗
By invitation
Real-World Use of an iPad-Based Light Therapy App, With Optional Biomarker Collection
Circadian Rhythms
Circadian OS, Inc · started 2026-07-17
📍 New York
NCT07744711 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Study to Find Out How Nerandomilast is Tolerated, Handled by the Body, and if it Helps Children and Adolescents With Interstitial Lung Disease (FIBRONEER-chILD)
Fibrosing Interstitial Lung Disease
Boehringer Ingelheim · started 2026-07-21
📍 California · Colorado · Maryland · Massachusetts · Minnesota · Ohio · Pennsylvania
NCT07366034 on ClinicalTrials.gov ↗
Recruiting Phase 1
A Study to Assess Adverse Events and How Intravenous (IV) Pivekimab Sunirine Moves Through the Body in Pediatric Participants With Relapsed or Refractory Acute Myeloid Leukemia (AML)
Acute Myeloid Leukemia
AbbVie · started 2026-05-20
📍 California · New York · Tennessee
NCT07306832 on ClinicalTrials.gov ↗
Recruiting Phase 2
A Study of NX-5948 in Adults With CLL/SLL Previously Treated With a Bruton's Tyrosine Kinase Inhibitor and a B-cell Lymphoma-2 Inhibitor (DAYBreak CLL-201)
Chronic Lymphocytic Leukemia (CLL), Small Lymphocytic Lymphoma (SLL)
Nurix Therapeutics, Inc. · started 2025-10-15
📍 California · Colorado · Florida · Indiana · Iowa · Maryland · Michigan · North Carolina
NCT07221500 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Study to Evaluate Adverse Events and Change in Disease Activity of Intravenous ABBV-706 Versus Standard of Care in Adult Participants With Relapsed/Refractory Small Cell Lung Cancer
Small Cell Lung Cancer
AbbVie · started 2026-07-02
📍 Alabama · Arizona · California · Florida · Georgia · Illinois · Indiana · Michigan
NCT07365241 on ClinicalTrials.gov ↗
Active Phase 1
DAREON™-9: A Study to Test How Well Different Doses of BI 764532 Are Tolerated by People With Small Cell Lung Cancer When Taken Together With a Single Agent Chemotherapy
Small Cell Lung Carcinoma (SCLC)
Boehringer Ingelheim · started 2024-02-14
📍 District of Columbia · Florida · Virginia
NCT05990738 on ClinicalTrials.gov ↗
Recruiting Phase 3
Long-Term Study to Evaluate the Safety and Efficacy in Participants With Primary Biliary Cholangitis of Saroglitazar Magnesium-V on Clinical Outcomes
Primary Biliary Cholangitis
Zydus Therapeutics Inc. · started 2026-03-24
📍 Georgia · Indiana · Texas
NCT07216235 on ClinicalTrials.gov ↗
Starting soon
Radicle RestTM VGI: A Study Assessing the Impact of Health and Wellness Products on Sleep and Related Health Outcomes
Sleep Disturbance
Radicle Science · started 2026-08-06
📍 California
NCT07744997 on ClinicalTrials.gov ↗
Recruiting Phase 1
Study of QUAIL-100 in Pediatric and Young Adult Participants With High-Risk Hematologic Malignancies Who Have Received a Hematopoietic Stem Cell Transplantation
Acute Leukemia, Myelodysplastic Syndrome
Laguna Biotherapeutics, Inc. · started 2026-08
📍 California
NCT07573111 on ClinicalTrials.gov ↗
Recruiting Phase 2
A Phase 2b Clinical Trial of YN001 in Adults With Coronary Atherosclerosis
Atherosclerosis, Coronary Artery Disease
Beijing Inno Medicine Co., Ltd. · started 2026-07-31
📍 Alabama · California · Florida · Illinois · Kansas · Missouri · North Carolina · Ohio
NCT07521007 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Study to Investigate the Efficacy and Safety of Bemdaneprocel in Adults Who Have Parkinson's Disease
Parkinsons Disease (PD)
BlueRock Therapeutics · started 2025-06-17
📍 Arizona · Arkansas · California · Colorado · District of Columbia · Florida · Illinois · Kansas
NCT06944522 on ClinicalTrials.gov ↗
By invitation
Continued Access to the Endogenex System for Participants in the ReCET Pivotal Study
Type 2 Diabetes Mellitus, Type2diabetes, Diabetes Mellitus, Type 2, Type 2 Diabetes
Endogenex, Inc. · started 2026-09
📍 Alabama · Florida · Illinois · Massachusetts · New Jersey · North Carolina · Texas
NCT07197788 on ClinicalTrials.gov ↗
Recruiting Phase 1
Phase 1 Study of C.001 in Retinal Degeneration
Geographic Atrophy, Stargardt Disease, RPE-mediated Maculopathy, Age Related Macular Degeneration
Cellio Therapeutics Inc · started 2026-04-07
📍 California
NCT07594236 on ClinicalTrials.gov ↗
By invitation
Database Linkage Study to Evaluate the Risk of Medullary Thyroid Carcinoma
Medullary Thyroid Carcinoma
Novo Nordisk A/S · started 2025-12-31
📍 New Jersey
NCT07713901 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Clinical Study of MK-8527 to Prevent Human Immunodeficiency Virus Type 1 (HIV-1) (MK-8527-011)
Human Immunodeficiency Virus (HIV), HIV Pre-Exposure Prophylaxis
Merck Sharp & Dohme LLC · started 2025-07-31
📍 Alabama · California · District of Columbia · Florida · Georgia · Illinois · Louisiana · Mississippi
NCT07044297 on ClinicalTrials.gov ↗
Recruiting Phase 2/Phase 3
A Study of the Efficacy and Safety of Danicamtiv in Participants With Symptomatic Genetic and Familial Dilated Cardiomyopathy
Symptomatic Genetic Dilated Cardiomyopathy
Kardigan, Inc. · started 2026-02-13
📍 Alabama · California · District of Columbia · Florida · Illinois · Louisiana · Maryland · Massachusetts
NCT07210723 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Phase 3 Trial of DT120 for Major Depressive Disorder (Ascend)
Major Depressive Disorder
Definium Therapeutics US, Inc. · started 2026-05-10
📍 Arizona · Arkansas · California · Colorado · Florida · Georgia · Illinois · Massachusetts
NCT07592689 on ClinicalTrials.gov ↗
Recruiting Phase 1
A Research Study Investigating How a New Medicine NNC0113-5840 Works in People With Overweight or Obesity
Obesity, Overweight
Novo Nordisk A/S · started 2026-05-01
📍 California · Maryland
NCT07566390 on ClinicalTrials.gov ↗
Recruiting Phase 1
Trial to Evaluate the Safety and Preliminary Efficacy of GEN1079 in Participants With Advanced Solid Tumors
Advanced Solid Tumors
Genmab · started 2026-04-07
📍 Connecticut · Michigan · New York
NCT07387068 on ClinicalTrials.gov ↗
Recruiting Phase 4
A Study Evaluating the Effectiveness and Safety of Risdiplam Administered as an Early Intervention in Pediatric Participants With Spinal Muscular Atrophy After Gene Therapy
Muscular Atrophy, Spinal
Hoffmann-La Roche · started 2024-05-30
📍 Arkansas · Colorado · Florida · Georgia · Illinois · Michigan · New York · Pennsylvania
NCT05861986 on ClinicalTrials.gov ↗
Recruiting Phase 2
Beamion PANTUMOR-1: A Study to Test Whether Zongertinib Helps People With Advanced Cancers With HER2 Alterations
Solid Tumours
Boehringer Ingelheim · started 2024-10-11
📍 Alaska · Arizona · California · Connecticut · Florida · Illinois · Indiana · Maryland
NCT06581432 on ClinicalTrials.gov ↗
Recruiting
Continuous Dual Aspiration Technique With Zoom System for Stroke
Ischemic Stroke, Acute Stroke
Imperative Care, Inc. · started 2026-03-24
📍 Alabama · California · Florida · Louisiana · Maryland · Minnesota · New York · Oklahoma
NCT07491952 on ClinicalTrials.gov ↗
Active Phase 1/Phase 2
GEN1046 Safety Trial in Patients With Malignant Solid Tumors
Solid Tumors
Genmab · started 2019-05-14
📍 Arizona · Connecticut · Florida · Georgia · Iowa · Kentucky · Michigan · Minnesota
NCT03917381 on ClinicalTrials.gov ↗
By invitation
A Long-Term Follow-Up Basket Study for Participants Treated With SynKIR Chimeric Antigen Receptor (CAR) T Cell Product
Cancer
Verismo Therapeutics · started 2025-01-27
📍 Colorado · Georgia · Kansas · New Jersey · Pennsylvania · Texas · Wisconsin
NCT06701201 on ClinicalTrials.gov ↗
Recruiting Phase 2/Phase 3
Evaluation of PLG0206 in Prevention of Recurrent Infection in Patients Undergoing Debridement, Antibiotics, and Implant Retention (DAIR) for Treatment of a Periprosthetic Joint Infection (PJI) Following Knee Arthroplasty
Prosthetic-joint Infection
Peptilogics · started 2026-02-03
📍 Florida · Louisiana · Maryland · Massachusetts · New York · North Carolina · Ohio · Pennsylvania
NCT07214311 on ClinicalTrials.gov ↗
Active Phase 2
Trial of Two Adagrasib Dosing Regimens in NSCLC With KRAS G12C Mutation (KRYSTAL 21)
Advanced Cancer, Metastatic Cancer, Malignant Neoplasm of Lung
Mirati Therapeutics Inc. · started 2024-02-01
📍 California · Missouri · North Carolina · Texas
NCT05853575 on ClinicalTrials.gov ↗
Recruiting Phase 3
Study Evaluating the Efficacy and Safety of RAP-219 in Adult Participants With Focal Seizures FOCUS-1
Focal Seizure, Epilepsy, Focal Epilepsy
Rapport Therapeutics Inc. · started 2026-06-05
📍 California · Indiana · Maryland · New Jersey · Pennsylvania · Virginia
NCT07563881 on ClinicalTrials.gov ↗
Active Phase 3
A Study of Apalutamide (ARN-509) in Men With Non-Metastatic Castration-Resistant Prostate Cancer
Prostatic Neoplasms
Aragon Pharmaceuticals, Inc. · started 2013-10-14
📍 Alabama · Alaska · Arizona · California · Colorado · District of Columbia · Florida · Idaho
NCT01946204 on ClinicalTrials.gov ↗
Active Phase 3
Sacituzumab Tirumotecan (MK-2870) Versus Pemetrexed and Carboplatin Combination Therapy in Participants With Epidermal Growth Factor (EGFR)-Mutated, Advanced Nonsquamous Non-small Cell Lung Cancer (NSCLC) Who Have Progressed on Prior EGFR Tyrosine Kinase Inhibitors (MK-2870-009)
Non-small Cell Lung Cancer (NSCLC)
Merck Sharp & Dohme LLC · started 2024-06-11
📍 California · Florida · Georgia · Michigan · Missouri · New Jersey · New York · North Dakota
NCT06305754 on ClinicalTrials.gov ↗
Active Phase 3
Randomized Clinical Trial Evaluating the Efficacy and Safety of Vormatrigine in Adults With Focal Seizures
Focal Epilepsy
Praxis Precision Medicines · started 2026-01-29
📍 Florida · New Jersey · New York · North Carolina · Texas
NCT07505004 on ClinicalTrials.gov ↗
Recruiting
THRIVE- THerapeutic IntravasculaR Ultrasound (TIVUS™) REnal Denervation System Versus Sham for the Adjunctive Treatment of Hypertension
Hypertension
SoniVie Inc. · started 2024-10-03
📍 Alabama · Arizona · Arkansas · California · Connecticut · Florida · Illinois · Louisiana
NCT06559891 on ClinicalTrials.gov ↗
Active
Continued Access Study to Evaluate Performance of the Organ Recovery Systems _LifePort® Liver Transporter System, a Machine Perfusion System, for Liver Transplant (PILOT™_CA)
Liver Transplantation
Organ Recovery Systems, Inc. · started 2022-09-19
📍 Illinois · New Jersey · Ohio · Utah
NCT05574361 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Long-Term Study of Elafibranor in Adult Participants With Primary Biliary Cholangitis
Primary Biliary Cholangitis (PBC)
Ipsen · started 2023-08-31
📍 Arizona · Arkansas · California · Colorado · Florida · Kansas · Louisiana · Michigan
NCT06016842 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Study of a Deuterated Psilocin Analog (CYB003) in Humans With Major Depressive Disorder
Major Depressive Disorder (MDD), Depression in Adults, Depression - Major Depressive Disorder, Depression Disorders
Cybin IRL Limited · started 2025-12-10
📍 Alabama · Arizona · Arkansas · California · Connecticut · Florida · Georgia · Illinois
NCT06793397 on ClinicalTrials.gov ↗
Starting soon Phase 3
A Study on the Immune Response and Safety of an Investigational Combined Measles, Mumps, Rubella and Varicella Vaccine, When Given to Healthy Children 4 to 6 Years of Age
Measles, Mumps, Rubella, Varicella (Chickenpox)
GlaxoSmithKline · started 2026-08-11
📍 Arkansas · California · Florida · Idaho · Illinois · Kentucky · Louisiana · Missouri
NCT07742644 on ClinicalTrials.gov ↗
Recruiting Phase 3
Sacituzumab Tirumotecan (MK-2870) Plus Pembrolizumab Versus TPC in TNBC Who Did Not Achieve pCR (MK-2870-012)
Triple-Negative Breast Cancer
Merck Sharp & Dohme LLC · started 2024-06-24
📍 Alabama · Arizona · California · Colorado · Connecticut · Florida · Georgia · Illinois
NCT06393374 on ClinicalTrials.gov ↗
Recruiting Phase 2
Belzutifan/MK-6482 for the Treatment of Advanced Pheochromocytoma/Paraganglioma (PPGL), Pancreatic Neuroendocrine Tumor (pNET), Von Hippel-Lindau (VHL) Disease-Associated Tumors, Advanced Gastrointestinal Stromal Tumor (wt GIST), or Solid Tumors With HIF-2α Related Genetic Alterations (MK-6482-015)
Pheochromocytoma/Paraganglioma, Pancreatic Neuroendocrine Tumor, Von Hippel-Lindau Disease, Advanced Gastrointestinal Stromal Tumor
Merck Sharp & Dohme LLC · started 2021-08-12
📍 California · Illinois · Iowa · Maryland · Massachusetts · Michigan · Missouri · New York
NCT04924075 on ClinicalTrials.gov ↗
Recruiting Phase 3
A Study to Investigate Cabotegravir Ultra Long-Acting (CAB ULA) Plus Rilpivirine Ultra Long-Acting (RPV ULA) in Adults and Adolescents With HIV Who Are Virologically Suppressed
HIV Infections
ViiV Healthcare · started 2026-06-25
📍 Arizona · California · Connecticut · District of Columbia · Florida · Georgia · Michigan · Missouri
NCT07650916 on ClinicalTrials.gov ↗
Active Phase 1
A Study to Evaluate the Pharmacokinetics, Safety, and Tolerability of Upadacitinib in Pediatric Subjects With Polyarticular Course Juvenile Idiopathic Arthritis
Juvenile Idiopathic Arthritis (JIA)
AbbVie · started 2019-06-24
📍 Illinois · Kentucky · Massachusetts · Ohio · Oregon · Pennsylvania · Washington
NCT03725007 on ClinicalTrials.gov ↗
Active Phase 3
Evaluation of Oral Tofacitinib in Children Aged 2 to 17 Years Old Suffering From Moderate to Severe Ulcerative Colitis
Ulcerative Colitis
Pfizer · started 2021-08-12
📍 California · Connecticut · Florida · Georgia · Massachusetts · New York · Ohio · Pennsylvania
NCT04624230 on ClinicalTrials.gov ↗
Recruiting Phase 1
Clinical Study of MK-4884 in Participants With Advanced or Metastatic Solid Tumors (MK-4884-001)
Malignant Neoplasm
Merck Sharp & Dohme LLC · started 2026-06-18
📍 Texas
NCT07600749 on ClinicalTrials.gov ↗
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Cite this page

Priya Life Science (2026). Clinical Trials in the USA Tracker. Available at: https://priyalifescience.com/clinical-trials-usa (Accessed: 5 August 2026).

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Source: ClinicalTrials.gov, U.S. National Library of Medicine — industry-sponsored studies in a recruiting status with at least one US site, most recently updated first, refreshed daily. This is a curated slice of the full registry, not every US trial. Listing here is informational and not medical advice; eligibility is determined by each study team. Patients should discuss participation with their clinician. Compare pay for the teams running these studies in our US Pharma Salary Guide, see who's behind them in the US Company Directory, or track approvals on the FDA Approvals Tracker. For Irish and EU sites, see our Ireland and EU trackers.