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Priya Life Science Clinical trial register
Trackers› Clinical trials› Advanced Solid Tumor
Clinical trial register · United Kingdom · industry-sponsored

Advanced Solid Tumor Trials in the UK, 2026

Every industry-sponsored study on the ClinicalTrials.gov registry that lists a UK site and is open, about to open, active-but-closed, or enrolling by invitation. This deliberately excludes academic and other non-industry sponsors — the full UK registry across all sponsors is far larger. UK studies may also be registered separately on ISRCTN.

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Source: ClinicalTrials.gov. Complete coverage of the industry-sponsored slice — all 2864 matching records are in this view (non-industry sponsors are out of scope by design, not truncated). Synced 18 Oct 2026, 03:15 UTC
2864
Studies in scope
industry-sponsored, all four open statuses
1380
Recruiting now
open to new participants
544
Lead sponsors
across recruiting studies
Top sites
London 12 Newcastle upon Tyne 4 Manchester 4 Sutton 4 Oxford 3
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Recruitment status
Phase
Target enrolment
to

Advanced Solid Tumor trials in the UK

15 of 2864 studies
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Status
Study
Lead sponsor
Phase
Enrol
UK sites
Start
Recruiting
BioNTech SE
Phase 1/2
1,438
Birmingham, Cardiff, Glasgow, Liverpool, London, Manchester, Newcastle upon Tyne, Southampton
2025-08-12
Recruiting
Anti-GD2 ADC M3554 in Advanced Solid Tumors
NCT06641908Advanced Solid Tumor
EMD Serono Research & Development Institute, Inc.
Phase 1
65
Sutton
2024-11-08
Recruiting
Study of Orally Administered MOMA-313 in Participants With Advanced or Metastatic Solid Tumors
NCT06545942Advanced Solid Tumor, Metastatic Solid Tumor, Prostate Cancer, Pancreas Cancer
MOMA Therapeutics
Phase 1
220
London, Manchester, Newcastle upon Tyne
2024-08-13
Recruiting
A Study of LY4052031 in Participants With Advanced or Metastatic Urothelial Cancer or Other Solid Tumors
NCT06465069Metastatic Solid Tumor, Recurrent Solid Tumor, Advanced Solid Tumor, Urinary Bladder Neoplasm
Eli Lilly and Company
Phase 1
460
London, Manchester
2024-07-01
Recruiting
A Study of MGC026 in Participants With Advanced Solid Tumors
NCT06242470Advanced Solid Tumor, Advanced Cancer, Metastatic Cancer, Squamous Cell Carcinoma of Head and Neck
MacroGenics
Phase 1
250
Oxford, Sutton
2024-03-06
Recruiting
A Study of HER3-DXd in Subjects With Locally Advanced or Metastatic Solid Tumors
NCT06172478Advanced Solid Tumor, Melanoma, Head and Neck Cancer, Gastric Cancer
Daiichi Sankyo
Phase 2
740
Cambridge, Coventry, London, Nottingham
2024-02-26
Active, closed
A Phase 1 Clinical Study of NXP900 in Subjects With Advanced Cancers
NCT05873686Advanced Solid Tumor, NSCLC (Non-small Cell Lung Cancer), Renal Cancer, Mesothelioma
DrugNXP900
Nuvectis Pharma, Inc.
Phase 1
140
Edinburgh, London
2023-10-26
Recruiting
A Study of PYX-201 in Advanced Solid Tumors
NCT05720117Solid Tumor, Advanced Solid Tumor
Pyxis Oncology, Inc
Phase 1
330
London
2023-03-14
Recruiting
First in Human Study of T3P-Y058-739 (T3P)
NCT05120596Advanced Solid Tumor
T3 Pharmaceuticals AG
Phase 1/2
100
Glasgow, Leeds, London, Southampton
2022-04-26
Active, closed
BicycleTx Limited
Phase 1/2
200
Sutton, Glasgow
2021-11-02
Recruiting
Debiopharm International SA
Phase 1
464
London
2021-04-30
Recruiting
Day One Biopharmaceuticals, Inc.
Phase 2
141
London, Newcastle upon Tyne
2021-04-22
Active, closed
Replimune, Inc.
Phase 1
123
Bebington, London, Oxford
2020-12-29
Recruiting
The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE)
NCT04585750Advanced Solid Tumor, Advanced Malignant Neoplasm, Metastatic Cancer, Metastatic Solid Tumor
PMV Pharmaceuticals, Inc
Phase 1/2
300
London, Newcastle upon Tyne
2020-10-29
Recruiting
A Study of Tulmimetostat DZR123 (CPI-0209) in Patients With Advanced Solid Tumors and Lymphomas
NCT04104776Advanced Solid Tumor, Diffuse Large B Cell Lymphoma, Lymphoma, T-Cell, Mesothelioma, Malignant
Novartis Pharmaceuticals
Phase 1/2
300
Bath, Leicester, London, Manchester, Oxford, Southampton, Sutton, Taunton
2019-09-18
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Cite this view

Priya Life Science (2026). Clinical trial register: industry-sponsored studies with a UK investigative site, filtered. Derived from ClinicalTrials.gov. Retrieved 18 October 2026. https://priyalifescience.com/clinical-trials-uk/condition/advanced-solid-tumor

Query this register directly
GET /api/trials?country=uk&status=recruiting&format=json Try it now →

About this register

This register is built from ClinicalTrials.gov, the trial registry run by the U.S. National Library of Medicine. It includes every industry-sponsored study on the registry that lists at least one investigative site in the UK and is recruiting, not yet recruiting, active but no longer recruiting, or enrolling by invitation: 2,864 studies in total at the last sync on 18 Oct 2026, 03:15 UTC. Academic and other non-industry sponsors are out of scope by design. The full list can be downloaded as CSV or queried as JSON through the register API.

This page shows the 15 of those studies listing the condition Advanced Solid Tumor.

How many Advanced Solid Tumor trials are recruiting in the UK?

12 of the 15 studies on this page are recruiting new participants as of the 18 Oct 2026, 03:15 UTC sync. A further 0 have not yet opened recruitment, 3 are active but closed to new participants, and 0 are enrolling by invitation only. Eligibility for any study is decided by its study team.

Summary by phase

Studies by phase (Advanced Solid Tumor), 15 studies
PhaseStudiesRecruitingShare
Phase 18653.3%
Phase 1/25433.3%
Phase 22213.3%

Most active sponsors

Lead sponsors with the most studies (Advanced Solid Tumor)
Lead sponsorStudiesRecruiting
BicycleTx Limited10
BioNTech SE11
Daiichi Sankyo11
Day One Biopharmaceuticals, Inc.11
Debiopharm International SA11
Eli Lilly and Company11
EMD Serono Research & Development Institute, Inc.11
MacroGenics11
MOMA Therapeutics11
Novartis Pharmaceuticals11
Listing here is informational and not medical advice; eligibility is determined by each study team. Compare pay for the teams running these studies in the UK Pharma Salary Guide, or see the Ireland, EU and USA registers.