Pulmonary Mechanics and Cerebral Oxygenation During Prone Lumbar Disc Surgery
Condition(s) studied
Investigational drug(s) / intervention(s)
Prone Positioning: Patients will be placed in the prone position as part of routine surgical care for lumbar disc surgery. The study will observe changes in respiratory mechanics and cerebral regional oxygen saturation before and after prone positioning. No positioning intervention will be assigned or modified for research purposes.
Study summary
This prospective observational study aims to evaluate the relationship between changes in respiratory mechanics and cerebral oxygenation in adult patients undergoing elective lumbar disc surgery in the prone position under general anesthesia.
Cerebral regional oxygen saturation will be monitored using bilateral frontal near-infrared spectroscopy (NIRS), while respiratory parameters including tidal volume, respiratory rate, peak airway pressure, plateau pressure, positive end-expiratory pressure, and dynamic compliance will be recorded from the anesthesia ventilator. Measurements will be obtained at predefined time points before and after positioning the patient prone and after returning to the supine position at the end of surgery.
No changes will be made to anesthesia, ventilation, medication doses, or surgical management for research purposes. All clinical care will be provided according to routine practice by the responsible anesthesia team. The study will investigate whether changes in respiratory mechanics during prone positioning are associated with changes in cerebral regional oxygen saturation.
Eligibility
Primary outcome measure(s)
- Change in Cerebral Regional Oxygen Saturation (rSO2) During Prone Positioning — Intraoperative, from baseline before prone positioning to return to the supine position at the end of surgery.
Bilateral frontal cerebral regional oxygen saturation (rSO2) will be measured using near-infrared spectroscopy (NIRS). Measurements will be recorded at baseline in the supine position (T0), 15 minutes (T1), 30 minutes (T2), 45 minutes (T3), and 60 minutes (T4) after prone positioning, and after return to the supine position at the end of surgery (T5).
Trial sites (1)
| Facility | City | Region | Status |
|---|---|---|---|
| Sancaktepe Sehit Prof. Dr. Ilhan Varank Training and Research Hospital | Istanbul | Istanbul | Recruiting |
More Sehit Prof. Dr. Ilhan Varank Sancaktepe Training and Research Hospital trials in Turkey
Other trials for the same condition
This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
View NCT07862257 on ClinicalTrials.gov ↗ ← All trials in Turkey