Ireland
--:--IST
Recruiting Observational

Total Intravenous Versus Inhalational Anesthesia in Patients Undergoing Hip Fracture Surgery

NCT07860996 · tracked via the Priya Life Science Turkey tracker
Phase
Observational
Started
2026-09-30
Last updated
2026-10-06

Condition(s) studied

Hip FracturePostoperative Recovery

Investigational drug(s) / intervention(s)

Propofol-based Total Intravenous AnesthesiaSevoflurane-based Inhalational Anesthesia

Propofol-based Total Intravenous Anesthesia: Propofol-based total intravenous anesthesia administered according to routine clinical practice during hip fracture surgery.

Sevoflurane-based Inhalational Anesthesia: Sevoflurane-based inhalational anesthesia administered according to routine clinical practice during hip fracture surgery.

Study summary

This prospective observational study aims to compare total intravenous anesthesia (TIVA) with sevoflurane-based inhalational anesthesia in patients aged 65 years and older undergoing hip fracture surgery under general anesthesia. The study will evaluate postoperative quality of recovery using the Quality of Recovery-40 (QoR-40) questionnaire and cognitive outcomes, including postoperative delirium and cognitive status. Pain scores, opioid consumption, recovery room stay, postoperative complications, and patient satisfaction will also be recorded. The anesthesia technique will be determined by the attending anesthesiologist as part of routine clinical practice, and the researchers will not interfere with the choice of anesthesia.

Eligibility

Sex
ALL
Min age
65 Years
Max age
—
Healthy volunteers
No
Inclusion Criteria: * Age 65 years or older * ASA physical status I-III * Scheduled to undergo elective or emergency hip fracture surgery under general anesthesia * Provision of informed consent by the patient and/or legal representative Exclusion Criteria: * Refusal to participate in the study * ASA physical status IV-V * Severe pre-existing neurological or psychiatric disorders, including advanced dementia or severe cognitive impairment preventing communication * Known hypersensitivity or allergy to propofol or sevoflurane * History of chronic heavy opioid or sedative substance use * Inability to communicate in Turkish or to understand and complete the QoR-40 questionnaire

Primary outcome measure(s)

  • Quality of Recovery-40 (QoR-40) Score on Postoperative Day 1 — Postoperative day 1
    Postoperative quality of recovery will be assessed using the Quality of Recovery-40 (QoR-40) questionnaire. The QoR-40 consists of 40 items evaluating five dimensions of recovery: physical comfort, emotional state, physical independence, psychological support, and pain. Higher total scores indicate better quality of recovery.

Trial sites (1)

FacilityCityRegionStatus
Sancaktepe Sehit Prof. Dr. Ilhan Varank Training and Research Hospital Istanbul Istanbul Recruiting
Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07860996 on ClinicalTrials.gov ↗ ← All trials in Turkey