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Clinical Trials in Turkey / NCT07856901
Starting soon Observational

Retinal and Choroidal Changes in Periodontal Disease

NCT07856901 · tracked via the Priya Life Science Turkey tracker
Sponsor
Zeliha Başak Çakır Erdil
Phase
Observational
Started
2026-10
Last updated
2026-10-05

Condition(s) studied

Periodontal DiseasesPeriodontal Diseases InflammationRetinal Thickening

Study summary

Advanced PeriodontitisIn this cross-sectional study, the relationship between periodontal disease severity and retinal and choroidal structural changes was evaluated using SD-OCT. Data from a total of 80 participants were examined. It was found that choroidal thickness increased and ganglion cell layer thickness decreased as periodontal disease severity increased, while no significant relationship was found in RNFL and IPL thicknesses. The findings support a possible association between periodontal disease and ocular structural changes.

Eligibility

Sex
ALL
Min age
20 Years
Max age
54 Years
Healthy volunteers
Accepted
Inclusion Criteria: Systemically healthy adults. Non-smokers (no current or previous tobacco use). Participants who underwent optical coherence tomography (OCT) imaging. Participants who provided written informed consent and agreed to participate in the study. Exclusion Criteria: Presence of any systemic disease. Current or former smokers. Participants with incomplete clinical or OCT data. Individuals who did not provide written informed consent. \-

Primary outcome measure(s)

  • Correlation Between Periodontal Disease Severity and Choroidal Thickness — Baseline
    The correlation between periodontal disease severity and choroidal thickness will be assessed using Spearman's correlation coefficient (rₛ). Periodontal disease severity will be assessed using probing pocket depth (PPD) and clinical attachment level (CAL), measured in millimeters (mm) using a periodontal probe. Choroidal thickness will be measured in micrometers (µm) using spectral-domain optical coherence tomography (SD-OCT).

Trial sites (1)

FacilityCityRegionStatus
Faculty of Dentistry, Adıyaman University Adıyaman Adıyaman Province

More Zeliha Başak Çakır Erdil trials in Turkey

Ozone Versus Conventional Socket Disinfection for Primary Dental Implant Stability Active, not recruiting
Root Coverage Performance of Restorative Materials in Class V Cavities Recruiting

Other trials for the same condition

Markers of Bone Destruction and Oxidative Stress in Peri-implantitis Recruiting
Evaluation of the Effect of Smoking on Pyroptosis in Periodontal Pathogenesis Active, not recruiting
Evaluation of Nucleotide-Binding Oligomerization Domain-Containing Protein (NOD) 1 and NOD 2 Starting soon
Evaluation of the Effectiveness of Odontogenic Grafts Obtained From Human Teeth on Bone Formation Enrolling by invitation
Evaluation of Salivary Gal-7, Gal-10 and MMP-9 Levels of Individuals With Different Periodontal Diseases Recruiting
Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07856901 on ClinicalTrials.gov ↗ ← All trials in Turkey