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Clinical Trials in Turkey / NCT07687680
Active, not recruiting Not applicable

Ozone Versus Conventional Socket Disinfection for Primary Dental Implant Stability

NCT07687680 · tracked via the Priya Life Science Turkey tracker
Sponsor
Zeliha Başak Çakır Erdil
Phase
Not applicable
Started
2025-11-18
Last updated
2026-07-20

Condition(s) studied

Dental Implant PlacementOzone Therapy

Investigational drug(s) / intervention(s)

Ozone Implant Site DisinfectionConventional Socket Disinfection

Ozone Implant Site Disinfection: Before dental implant placement, the implant site assigned to the experimental intervention is disinfected using ozone according to the study protocol. In this randomized split-mouth design, each participant receives ozone disinfection at one implant site, while the paired contralateral or symmetrical implant site receives conventional disinfection. Implant stability is evaluated immediately after implant placement using insertion torque and resonance frequency analysis (ISQ), and again after 3 months using ISQ.

Conventional Socket Disinfection: Before dental implant placement, the implant site assigned to the control intervention is disinfected using the conventional disinfection protocol. In this randomized split-mouth design, each participant receives conventional disinfection at one implant site, while the paired contralateral or symmetrical implant site receives ozone disinfection. Implant stability is evaluated immediately after implant placement using insertion torque and resonance frequency analysis (ISQ), and again after 3 months using ISQ.

Study summary

This randomized split-mouth controlled clinical trial aims to compare the effects of ozone and conventional implant site disinfection on primary and early secondary implant stability. Systemically healthy adults requiring at least two dental implants in symmetrical or contralateral edentulous sites will receive ozone disinfection at one implant site and conventional disinfection at the paired site according to a randomized allocation. Implant stability will be assessed immediately after implant placement using insertion torque and resonance frequency analysis (Implant Stability Quotient, ISQ), and secondary stability will be evaluated by ISQ measurements at the 3-month follow-up during healing abutment placement. The study will determine whether ozone disinfection improves implant stability during the early osseointegration period.

Eligibility

Sex
ALL
Min age
18 Years
Max age
65 Years
Healthy volunteers
No
Inclusion Criteria: * Adults aged 18 years or older. * Systemically healthy individuals requiring at least two dental implants. * Presence of symmetrical or contralateral edentulous sites suitable for dental implant placement. * Adequate bone volume for implant placement without the need for simultaneous bone augmentation. * Ability and willingness to provide written informed consent and comply with the study protocol. Exclusion Criteria: * Adults aged 18 years or older. * Systemically healthy individuals requiring at least two dental implants. * Presence of symmetrical or contralateral edentulous sites suitable for dental implant placement. * Adequate bone volume for implant placement without the need for simultaneous bone augmentation. * Ability and willingness to provide written informed consent and comply with the study protocol.

Primary outcome measure(s)

Trial sites (1)

FacilityCityRegionStatus
Faculty of Dentistry, Adıyaman University Adıyaman Merkez

More Zeliha Başak Çakır Erdil trials in Turkey

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Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07687680 on ClinicalTrials.gov ↗ ← All trials in Turkey