The Relationship Between Hypotension and Tissue O2 in Invasive Eadyn During Anesthesia Induction in Open Heart Surgery

Condition(s) studied

Investigational drug(s) / intervention(s)

mostcare hemodynamic monitor: Invasive hemodynamic variables including dynamic arterial elastance (Eadyn), stroke volume variation (SVV), pulse pressure variation (PPV), cardiac index (CI), oxygen delivery (DO₂), and cardiac power output (CPO) were obtained using the MostCare monitor.

Masimo NIRS: Cerebral and renal tissue oxygen saturation(rso2) values were measured using the Masimo device.

Hemodynamic Measurements on Standart Monitoring: Heart rate and peripheral oxygen saturation were measured using standard noninvasive monitoring.

Study summary

Our aim is to identify patients who may experience hypotension during anesthesia induction. Intraoperative hemodynamic stability plays an important role in tissue oxygenation. Although the duration of hypotension can be kept short with the necessary interventions, it is important that hypotension is predictable in order to prevent intraoperative complications and postoperative organ damage.

40 patients scheduled for open heart surgery will be monitored from one minute before anesthesia is administered until ten minutes after. Patients will be divided into two groups based on the presence or absence of hypotension during the monitoring period. All patients will be monitored according to a standardized procedure. Demographic data, non-invasive and invasive hemodynamic parameters, primarily Eadyn, and cerebral and renal tissue saturation data will be collected. Moreover, vasopressor administration in response to hypotension will be recorded.

Eligibility

Primary outcome measure(s)

• Eadyn — Perioperative
  Dynamic Arterial Elastance
• rso2 — Perioperative
  Cerebral and Kidney Regional Saturation
• Intraoperative hypotension — perioperative
  Explanatory outcome

Trial sites (1)

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