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Active, not recruiting Not applicable

Recto-intercostal Block for Coronary Artery Bypass Grafting

NCT06418100 · tracked via the Priya Life Science Turkey tracker
Phase
Not applicable
Started
2024-03-01
Last updated
2025-03-19

Condition(s) studied

Coronary Artery DiseasePeripheral Nerve BlocksSternotomy

Investigational drug(s) / intervention(s)

The recto intercostal fascial plane block

The recto intercostal fascial plane block: After ensuring aseptic conditions, the high-frequency linear ultrasound probe was used to detect the rectus abdominis muscle and the 6-7th costal cartilage as described by Tulgar et al. After rotating and shifting the transducer, 6-7th costal cartilages, the rectus abdominis muscle, and intercostal muscles between the cartilages were confirmed. The primary investigator (B.C.) directed the needle tip caudad in the cephalic direction in-plainly, and 20 ml 0,25% bupivacaine was injected bilaterally into the plane between the costal cartilage and the rectus abdominis muscle following negative aspiration.

Study summary

This interventional study aims to learn about the postoperative analgesic efficacy of a new fascial plane block, recto-intercostal fascial plane block, at coronary artery bypass grafting with sternotomy. There will be two groups, one of which will be the control group, and the other will be the study group randomly receiving postoperative recto-intercostal fascial plane block.

The main questions it aims to answer are the effect of this new block on postoperative opioid consumption and pain scores. Also, postoperative outcomes related to respiratory ( postoperative oxygenation and atelectasis score), hemodynamic functions ( newly developed arrhythmias), total postanesthesia care unit stay, and hospital stay will be questioned.

Eligibility

Sex
ALL
Min age
18 Years
Max age
80 Years
Healthy volunteers
No
Inclusion Criteria: * patients who will undergo CABG surgery with sternotomy * patients who have an American Society of Anesthesiologists (ASA) Physical Status classification of III to IV Exclusion Criteria: * refusal to participate * a history of neurological deficits or neuropathy affecting the thoracal innervation * infection at the site of block application * allergy to local anesthetics * epilepsy or treatment with antipsychotics * abuse of alcohol or drugs * previous surgery distorting the anatomy of the sternum, thorax or upper abdominal area * severe organ dysfunction ( kidney, liver and other); patients who fail at weaning after 12 hours of surgery.

Primary outcome measure(s)

  • Total rescue analgesic — postoperative 24 hour
    . From the beginning of acclaimed arousal till the 24th hour, rescue analgesia as tramadol 100 mg (maximum daily dose 400 mg) is applied if NRS over 4 or with the patient's request.

Trial sites (1)

FacilityCityRegionStatus
Haseki Training and Research Hospital Istanbul Sultangazi
Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT06418100 on ClinicalTrials.gov ↗ ← All trials in Turkey