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Clinical Trials in Turkey / NCT07379944
Starting soon Not applicable

Guided Visualization Meditation for Reducing Surgical Stress Response in Cardiac Surgery Patients

NCT07379944 · tracked via the Priya Life Science Turkey tracker
Sponsor
University of Gaziantep
Phase
Not applicable
Started
2026-01-15
Last updated
2026-02-02

Condition(s) studied

Cardiac SurgerySurgical Stress ResponseCoronary Artery DiseasePostoperative StressAnxiety

Investigational drug(s) / intervention(s)

Guided Visualization Meditation

Guided Visualization Meditation: A 15-20 minute guided visualization audio session including verbal imagery and relaxation techniques. Delivered via headphones twice daily on the preoperative day, surgery day, and postoperative day 1.

Study summary

This study aims to evaluate whether guided visualization meditation can reduce the surgical stress response in patients undergoing open-heart surgery. Surgical stress response includes changes in hormones, blood glucose, and anxiety levels that occur before and after major surgery. Guided visualization meditation is a non-invasive relaxation technique that uses calming audio instructions to help patients imagine peaceful scenes and reduce stress.

In this study, patients scheduled for cardiac surgery will be assigned to one of two groups: an intervention group that receives guided visualization meditation and a control group that receives standard care only. Patients in the intervention group will listen to an audio recording containing guided visualization and calming background music through headphones. Sessions will be provided twice on the day before surgery, twice on the day of surgery, and twice on the first postoperative day.

To evaluate the effects of the intervention, blood samples will be collected to measure cortisol, glucose, and insulin levels. Anxiety levels will be assessed using the State-Trait Anxiety Inventory (STAI-I and STAI-II), and pain will be measured using a visual pain scale. These measurements will be performed at three specific time points: one day before surgery, six hours after extubation, and one day post-surgery.

The goal of this research is to determine whether guided visualization meditation can help reduce stress-related physiological and psychological changes in patients undergoing cardiac surgery. If effective, this method may offer a simple, safe, and supportive strategy to improve recovery and overall patient well-being.

Eligibility

Sex
ALL
Min age
18 Years
Max age
—
Healthy volunteers
No
Inclusion Criteria: * Adults aged 18 years or older * Scheduled to undergo open-heart surgery * ASA physical status I-II * First-time cardiac surgery * On-pump, median sternotomy technique planned * Mild to moderate intraoperative hypothermia protocol * No diagnosed psychiatric disorder * Not using psychotropic medications * No endocrine disorders affecting cortisol (e.g., Addison's disease, Cushing's syndrome) * Not taking corticosteroid medications * Glasgow Coma Score = 15 postoperatively * No perioperative complications that may interfere with participation * Able and willing to provide informed consent Exclusion Criteria: * Prolonged or complicated surgery * Withdrawal of consent at any stage * Postoperative altered consciousness (GCS \< 15) * Perioperative administration of corticosteroids * Severe intraoperative complications * Surgery cancelled or rescheduled * Hearing impairment preventing participation in auditory intervention * Any condition clinically judged by the investigator to interfere with study participation

Primary outcome measure(s)

  • Serum Cortisol Level — One day before surgery, six hours after extubation on the day of surgery, and one day after surgery
    Serum cortisol levels will be measured at three perioperative time points to evaluate the neuroendocrine surgical stress response. A reduction in cortisol levels in the intervention group compared with the control group will indicate the effectiveness of guided visualization meditation.

Trial sites (1)

FacilityCityRegionStatus
Gaziantep University Gaziantep Şehitkamil

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Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07379944 on ClinicalTrials.gov ↗ ← All trials in Turkey