Comparison of the Factors Affecting PSI and BIS Values in Monitoring Anesthetic Depth During Open-Heart Surgery

Condition(s) studied

Investigational drug(s) / intervention(s)

anesthesia depth monitorizing, awareness: Investigation of BIS and PSI Monitoring Methods for Anesthetic Depth and the Factors Affecting These Methods in Open-Heart Surgery

Study summary

Measurement of anesthetic depth has long been a subject of investigation, aiming to titrate anesthetic agents appropriately and to prevent intraoperative awareness and consciousness. Many patients undergoing surgery experience fear and anxiety regarding the possibility of remaining conscious, perceiving pain, and being unable to move during anesthesia. Intraoperative awareness-defined as consciousness during anesthesia with explicit recall afterward-is a distressing condition that can lead to post-traumatic stress disorder.

However, aiming for excessively deep anesthesia to avoid the possibility of awareness during surgery is not recommended, as it may result in hemodynamic instability due to the effects of anesthetic agents and may impair postoperative cognitive functions, particularly in the elderly population.

Common methods used in monitoring anesthetic depth include observing sweating, lacrimation, pupillary dilation, heart rate variability, and blood pressure. However, some of these are subjective and may not always be reliable indicators.

Electroencephalogram (EEG)-based monitors such as the Bispectral Index (BIS) and the Patient State Index (PSI) offer more reliable and objective means of monitoring anesthetic depth. These monitors provide numerical values between 0 (indicating unconsciousness) and 100 (indicating full alertness) based on proprietary algorithms, offering valuable insight into the patient's anesthetic state.

"Our aim is to examine BIS and PSI values and to investigate the factors that influence these parameters."

Eligibility

Primary outcome measure(s)

• The primary objective of this study is to measure the correlation between BIS and PSI values, which are parameters used to monitor the depth of anesthesia during open-heart surgery. — Data will be collected over a 12-month period and subjected to statistical analysis.
  BIS (Bispectral Index) is a monitoring method that uses EEG (electroencephalogram) data to measure the depth of anesthesia. It has been used for a long time to assess anesthetic depth. PSI (Patient State Index) is a monitoring method that has become more popular in recent years for measuring the depth of anesthesia. The recommended reference ranges for anesthetic depth are 40-60 for BIS and 25-50 for PSI. The primary objective of this study is to measure the correlation between PSI and BIS values during open-heart surgery.

Trial sites (1)

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