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Clinical Trials in Turkey / NCT07799155
Recruiting Not applicable

TFESI and Neuropathic Pain in Lumbosacral Radiculopathy

NCT07799155 · tracked via the Priya Life Science Turkey tracker
Sponsor
Marmara University
Phase
Not applicable
Started
2026-08-11
Last updated
2026-09-02

Condition(s) studied

Lumbosacral RadiculopathyNeuropathic Pain From Lumbosacral RadiculopathyDisc Herniation With Radiculopathy

Investigational drug(s) / intervention(s)

Transforaminal Epidural Steroid Injections

Transforaminal Epidural Steroid Injections: Transforaminal epidural steroid injection will be performed under fluoroscopic guidance for the treatment of lumbosacral radiculopathy.

Study summary

Patients with lumbosacral radiculopathy frequently experience neuropathic pain due to nerve root compression. Transforaminal epidural steroid injection (TFESI) is commonly used for pain relief in these patients. This study aims to evaluate the effect of TFESI on neuropathic pain severity using the Neuropathic Pain Scale (NPS) in patients with lumbosacral radiculopathy. Clinical outcomes before and after the procedure will be compared.

Eligibility

Sex
ALL
Min age
18 Years
Max age
65 Years
Healthy volunteers
No
Inclusion Criteria: * Adults aged 18 years and older * Patients diagnosed with lumbosacral radiculopathy based on clinical evaluation and lumbar MRI findings * Presence of neuropathic pain symptoms associated with lumbosacral radiculopathy * Patients scheduled to undergo transforaminal epidural steroid injection (TFESI) * Patients able to understand and complete the study questionnaires and scales * Voluntary written informed consent provided Exclusion Criteria: * Previous lumbar spinal surgery * Cauda equina syndrome or progressive neurological deficit * Spinal malignancy, infection, or acute vertebral fracture * Pregnancy or breastfeeding * Coagulation disorders or current anticoagulant therapy contraindicating injection procedures * Known allergy to contrast agents, local anesthetics, or corticosteroids * Severe uncontrolled systemic disease * Cognitive impairment preventing completion of assessment scales * Patients unwilling to participate or unable to attend follow-up visits

Primary outcome measure(s)

  • Change in Neuropathic Pain Severity Assessed by the Neuropathic Pain Scale (NPS) — Baseline, 3 weeks after intervention, and 3 months after intervention
    hange in Neuropathic Pain Severity Assessed by the Neuropathic Pain Scale (NPS) The primary outcome measure is the change in neuropathic pain severity assessed using the Neuropathic Pain Scale (NPS) before and after transforaminal epidural steroid injection (TFESI) in patients with lumbosacral radiculopathy. The NPS ranges from 0 to 100, with higher scores indicating greater neuropathic pain severity (worse outcomes). Changes in NPS scores will be assessed from baseline to 3 weeks and 3 months after the intervention.

Trial sites (1)

FacilityCityRegionStatus
Marmara University Pendik Training and Research Hospital, Department of Physical Medicine and Rehabilitation" Istanbul Istanbul Recruiting

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Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07799155 on ClinicalTrials.gov ↗ ← All trials in Turkey