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Starting soon Observational

The Effect of Inspiratory Exercises on Diaphragm and Intercostal Muscle Thickness in Stroke Patients

NCT07206641 · tracked via the Priya Life Science Turkey tracker
Phase
Observational
Started
2025-12-01
Last updated
2025-11-18

Condition(s) studied

Stroke

Study summary

The aim of this study is to investigate the effect of inspiratory muscle strengthening exercises on bilateral parasternal intercostal muscle thickness and bilateral diaphragm muscle thickness in stroke patients and to present new data on whether the possible effect on the affected side can be associated with changes in respiratory parameters. Furthermore, as previous literature has shown that 4-week exercise programs are more effective than \>6-week exercise programs, an interim assessment is planned for the second week of treatment in this study to evaluate shorter-term changes. Four weeks after completion of the exercise program (in the 8th week), patients will be re-evaluated to track potential short-term effects.

Eligibility

Sex
ALL
Min age
18 Years
Max age
65 Years
Healthy volunteers
No
Inclusion Criteria: * Patients with a history of ischemic or hemorrhagic stroke * Aged 18-65 years Exclusion Criteria: * Presence of concomitant acute or chronic lung disease * History of thoracic or abdominal surgery * Presence of another neuromuscular disease * Patients with aphasia or impaired cognition * Severe heart disease * Active cancer * Mini-Mental State Examination (MMSE) score ≤ 24 * Active smoking

Primary outcome measure(s)

  • Diaphragm muscle thickness — Will be performed using an ultrasound device before treatment, at the 2nd week of treatment, at the end of treatment (4th week), and 4 weeks after the completion of treatment (8th week).
    In this study, ultrasonography will be used to examine the structure and function of the muscle and to measure muscle thickness at the end of inspiration and expiration.
  • Intercostal muscle thickness — Will be performed using an ultrasound device before treatment, at the 2nd week of treatment, at the end of treatment (4th week), and 4 weeks after the completion of treatment (8th week).
    In this study, ultrasonography will be used to examine the structure and function of the muscle and to measure muscle thickness at the end of inspiration and expiration.

Trial sites (1)

FacilityCityRegionStatus
Marmara Üniversitesi Tıp Fakültesi, Istanbul, Maltepe 34854 Istanbul Istanbul
Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07206641 on ClinicalTrials.gov ↗ ← All trials in Turkey