Noninvasive Artificial Venous Stasis for Reperfusion in STEMI

Inclusion Criteria: * Having presented within the first 12 hours of symptom onset Being hemodynamically stable (Killip Class I-II) * STEMI diagnosis confirmed by coronary angiography * Primary PCI (percutaneous coronary intervention) scheduled * No pathology in the upper extremity that would prevent cuff application * Be capable of providing informed consent and provide consent Exclusion Criteria: * Presence of cardiogenic shock (systolic blood pressure \< 90 mmHg and Killip Class III-IV) * Cardiac arrest occurring before or after the procedure * Need for resuscitation following failed thrombolysis * History of prior coronary artery bypass surgery * Concurrent acute aortic dissection * Venous thromboembolism or pulmonary embolism * History of an acute infection within the past 7 days * Chronic kidney disease requiring erythropoietin therapy or currently undergoing hemodialysis * Presence of liver failure or a hematologic disorder * Presence of any chronic inflammatory or autoimmune disease * History of any known malignancy (cancer) * Current treatment with glibenclamide, corticosteroids, antioxidant vitamins, or cyclosporine at the time of enrollment * History of chronic (daily) alcohol consumption * Contraindications to aspirin and/or clopidogrel * Failure to confirm a STEMI diagnosis via coronary angiography * Inability to provide informed consent * Pregnancy * First 6 months postpartum Conditions in which the administration of thrombolytics is contraindicated