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Clinical Trials in Turkey / NCT07367009
Active, not recruiting Observational

Effect of Combined Adductor Canal and AFCN Block on Postoperative Inflammation

NCT07367009 · tracked via the Priya Life Science Turkey tracker
Sponsor
Fatih Sultan Mehmet Training and Research Hospital
Phase
Observational
Started
2026-01-19
Last updated
2026-04-07

Condition(s) studied

Total Knee Anthroplasty

Study summary

The aim of this thesis is to evaluate the effects of adding an anterior femoral cutaneous nerve (AFCN) block to the adductor canal block used for postoperative analgesia after total knee arthroplasty on the postoperative inflammatory response, as assessed by inflammatory biomarkers including NLR, PLR, AISI, and CAR.

Eligibility

Sex
ALL
Min age
18 Years
Max age
—
Healthy volunteers
No
Inclusion Criteria: * • Patients scheduled for elective unilateral total knee arthroplasty under spinal anesthesia * Aged 18 years and older * Body mass index (BMI) \<40 kg/m² * ASA physical status I-III * Provision of written informed consent Exclusion Criteria:• Emergency surgery * Revision or bilateral surgery * General anesthesia or conversion to general anesthesia due to failed block * BMI ≥40 kg/m² * ASA physical status \>III * Local infection, hematoma, previous surgery, or deformity at the block site * Coagulopathy or history of hematologic, renal, or hepatic disease; advanced respiratory or cardiac failure; malignancy * Use of anticoagulant therapy * History of local anesthetic allergy or toxicity * Impaired cooperation, Alzheimer's disease, dementia, psychiatric or neurological disorders, or language/communication barriers * Chronic analgesic use, chronic alcohol consumption, or substance abuse * Refusal to participate in the study

Primary outcome measure(s)

  • assessment of post operative inflammatuar markes — it will be recorded at 0, 15, and 30 minutes in the PACU, and at 2, 4, 8, 12, and 24 hours on the ward.
    The primary objective of this observational study is to evaluate the effect of adding an anterior femoral cutaneous nerve block to the adductor canal block on the inflammatory response, as assessed by biomarkers such as NLR, PLR, AISI, and CAR, in patients undergoing total knee arthroplasty.

Trial sites (1)

FacilityCityRegionStatus
Fatih Sultan Mehmet Training and Research Hospital Istanbul ataşehir

More Fatih Sultan Mehmet Training and Research Hospital trials in Turkey

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Other trials for the same condition

Programmed Intermittent Epidural Bolus Versus Continuous Epidural Infusion for Postoperative Analgesia After Total Knee Arthroplasty Starting soon
"The Effect of AI-Assisted Mobilization Education on Kinesiophobia and Readiness for Hospital Discharge in Patients Undergoing Total Knee Arthroplasty'' Recruiting
Proximal Spread in Adductor Canal Block(ACB) Active, not recruiting
Drain Removal Before Versus After CPM in Primary Total Knee Arthroplasty Active, not recruiting
Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07367009 on ClinicalTrials.gov ↗ ← All trials in Turkey