This study shows that in craniotomy patients using a skull pin head holder, an ultrasound-guided scalp block reduces perioperative opioid consumption, improves hemodynamic stability, and decreases the inflammatory response.
Eligibility
Sex
ALL
Min age
18 Years
Max age
—
Healthy volunteers
No
Inclusion Criteria:
* Aged 18 years and older
* Scheduled for elective intracranial surgery with skull pin head holder fixation
* Classified as American Society of Anesthesiologists (ASA) physical status I-III
* Provided written informed consent in the preoperative period
Exclusion Criteria:
* Allergy to local anesthetics
* Coagulopathy or anticoagulant use
* Local infection at injection site
* Pregnancy or breastfeeding
* Chronic opioid use (\>3 months) or chronic pain syndrome
* Severe psychiatric disorders affecting pain assessment
* Emergency surgery
* Active infection or rheumatic disease
* Hematological disease or malignancy (active or within 5 years)
* Recent use of biological agents, chemotherapy, or corticosteroids (within 30 days)
* NSAID use within 24 hours before surgery
* Advanced organ failure (NYHA III-IV, Child-Pugh C, eGFR \<30 mL/min)
* Refusal to participate
* Communication difficulties preventing pain assessment
Primary outcome measure(s)
Total opioid consumption within 24 hours postoperatively (morphine milligram equivalents, mg) — 0-24 hours postoperatively All opioid analgesics administered within 24 hours postoperatively will be converted to morphine milligram equivalents (mg) for each participant. The outcome will be reported as a single total value per participant.
Trial sites (1)
Facility
City
Region
Status
Fatih Sultan Mehmet Training and Research Hospital
Istanbul
ataşehir
More Fatih Sultan Mehmet Training and Research Hospital trials in Turkey
This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
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