Ireland
--:--IST
Starting soon Observational

Laryngeal Edema Assessment by Cuff Leak Test and Ultrasound in ICU Patients and Its Relationship With Weaning Success

NCT07523828 · tracked via the Priya Life Science Turkey tracker
Phase
Observational
Started
2026-04-08
Last updated
2026-04-13

Condition(s) studied

Laryngeal Edema

Study summary

This study evaluates laryngeal edema in ICU patients during weaning from mechanical ventilation. It compares the cuff leak test and ultrasound-based laryngeal air column measurements in predicting weaning success. Ultrasound offers a non-invasive and real-time alternative for airway assessment. The study also examines post-extubation complications such as stridor, sore throat, dysphonia, and dysphagia.

Eligibility

Sex
ALL
Min age
18 Years
Max age
—
Healthy volunteers
No
Inclusion Criteria: * Patients who have been intubated and receiving invasive mechanical ventilation for at least 24 hours in the Intensive Care Unit of Fatih Sultan Mehmet Training and Research Hospital and who are considered by the intensive care physician to be ready for weaning from mechanical ventilation: * Patients over 18 years of age * Patients who have given their voluntary consent Exclusion Criteria: * Patients under 18 years of age * Patients with a history of oral cavity surgery such as direct laryngoscopy and biopsy, microlaryngoscopic surgery, tonsillectomy, adenoidectomy, soft palate, oropharynx, hypopharynx, larynx and trachea, * Patients with a history of allergy, asthma, reflux, upper respiratory tract viral or fungal infections, and cancer surgery, * Patients who received radiotherapy to the neck region, or who had more than one intubation attempt in the previous year, * Tracheostomized patients, patients with upper respiratory tract obstruction, vocal cord paralysis, and patients with stridor clinical picture before intubation, * Patients for whom voluntary consent cannot be obtained

Primary outcome measure(s)

  • Can pre-weaning laryngeal edema be used to predict weaning success? — Within 24 hours prior to extubation and during the weaning process
    To evaluate whether laryngeal edema measured prior to weaning can predict weaning success in mechanically ventilated ICU patients.

Trial sites (1)

FacilityCityRegionStatus
Fatih Sultan Mehmet Training and Research Hospital Istanbul Ataşehir
Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07523828 on ClinicalTrials.gov ↗ ← All trials in Turkey