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Clinical Trials in Turkey / NCT07326293
Recruiting Observational

The Effectiveness of Oxygen Reserve Index in Early Detection of Desaturation in Geriatric Patients Scheduled for Oncological Surgery

NCT07326293 · tracked via the Priya Life Science Turkey tracker
Sponsor
Ankara City Hospital Bilkent
Phase
Observational
Started
2025-12-16
Last updated
2026-01-08

Condition(s) studied

DesaturationApnea, HypoxiaOxygen Reserve Index

Study summary

This prospective observational study aims to evaluate the relationship between the Oxygen Reserve Index (ORI) and tolerable apnea time in geriatric patients undergoing elective oncologic surgery under general anesthesia.

Patients aged 65 years and older will be monitored using standard anesthesia monitoring and Masimo Rainbow SET® Pulse CO-Oximetry during anesthesia induction and tracheal intubation.

Tolerable apnea time will be defined as the duration from the end of ventilation after intubation to a decrease in peripheral oxygen saturation (SpO₂) to 94%.

The primary objective is to assess the association between ORI warning time and tolerable apnea time. Secondary objectives include evaluating the association between ORI values, arterial blood gas parameters at predefined time points, and the Clinical Frailty Scale.

Eligibility

Sex
ALL
Min age
65 Years
Max age
100 Years
Healthy volunteers
No
Inclusion criteria for the files/records/materials to be included in the study: Records of patients aged 65 years and older, classified as ASA physical status I-III, who are scheduled for elective oncologic surgery. Exclusion criteria for the files/records/materials to be included in the study: Records of patients with advanced coronary artery disease; advanced heart failure and/or valvular heart disease; carotid artery stenosis; left ventricular ejection fraction below 30%; rapid atrial fibrillation; body mass index (BMI) greater than 35 kg/m²; anticipated difficult airway; advanced-stage malignancy; or dementia.

Primary outcome measure(s)

  • The primary outcome measure is the association between Oxygen Reserve Index (ORI) warning time and tolerable apnea time. ORI warning time is defined as the time interval from the onset of the ORI alarm triggered by a downward trend to the decrease of per — Peri-induction period at predefined time points baseline; after 3 minutes of preoxygenation; after 2 minutes of bag-mask ventilation following intubation; during apnea at SpO₂ 94%; and after 2 minutes of ventilation with 100% oxygen
    The primary outcome measure is the association between Oxygen Reserve Index (ORI) warning time and tolerable apnea time. ORI warning time is defined as the time interval from the onset of the ORI alarm triggered by a downward trend to the decrease of peripheral oxygen saturation (SpO₂) to 94%. Tolerable apnea time is defined as the duration from the end of ventilation after tracheal intubation to the decrease of SpO₂ to 94%.

Trial sites (1)

FacilityCityRegionStatus
Ankara Bilkent City Hospital Ankara Çankaya Recruiting

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Other trials for the same condition

Comparison of the Time to Reach End-Tidal Oxygen Value of 90 and Oxygen Reserve Index Decline Times During Preoxygenation in Sarcopenic and Non-Sarcopenic Patients Starting soon
Oxygen Reserve Index (ORi) in Identifying Desaturation Starting soon
The Role of Oxygen Reserve Index (ORi) in Apneic Ventilation Starting soon
Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07326293 on ClinicalTrials.gov ↗ ← All trials in Turkey