Exercise Intensity and Postprandial Effects of Breaking Sedentary Behavior in Overweight Adults

Condition(s) studied

Investigational drug(s) / intervention(s)

Aerobic Exercise Intervention: In the aerobic exercise condition, participants will perform 2 minutes of moderate-intensity (%50 Wattmax) continuous cycling.

Sprint Exercise Intervention: In the sprint condition, participants will complete a 10-second sprint at %200 Wattmax level, as determined during the preliminary test.

Sedentary Behaviour Intervention: Participants will remain seated for a total duration of 7 hours. During this period, they will be instructed to minimize excessive movement and will only be permitted to rise from the chair for voiding purposes.

Study summary

The purpose of this study is twofold: (1) to determine whether breaking up prolonged sitting with aerobic or sprint cycling breaks reduces postprandial blood glucose, insulin, CRP, and blood pressure, which are established risk markers for cardiometabolic diseases; and (2) to assess substrate oxidation during this period in order to identify which exercise condition promotes the greatest increase in fat oxidation.

Eligibility

Primary outcome measure(s)

• Insulin — 7 hour for each experimental condition
  Postprandial insulin. Net incremental area under the curve and total area under the curve for each 7 h condition will be calculated for insulin.

Trial sites (1)

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