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Clinical Trials in Turkey / NCT07545499
Recruiting Observational

Physical Functions and Lifestyle Behaviours in Post-COVID-19 Syndrome Based on Circadian Rhythms

NCT07545499 · tracked via the Priya Life Science Turkey tracker
Sponsor
Hacettepe University
Phase
Observational
Started
2025-05-22
Last updated
2026-04-22

Condition(s) studied

Post-COVID-19 Syndrome

Study summary

Post-COVID-19 syndrome is associated with persistent symptoms such as fatigue, reduced physical activity, and impaired respiratory function. Circadian rhythm differences (chronotype) may influence lifestyle behaviors including physical activity, nutrition, and sleep patterns.

This observational cross-sectional study aims to compare respiratory muscle strength, physical activity levels, and nutritional habits among individuals with post-COVID-19 syndrome according to their chronotype (morning, intermediate, and evening types).

Additionally, genetic analysis of the CLOCK gene polymorphism will be performed to support objective evaluation of circadian rhythm differences. The findings of this study may help to better understand the role of circadian rhythm in post-COVID-19 syndrome and contribute to the development of individualized rehabilitation and lifestyle interventions.

Eligibility

Sex
ALL
Min age
18 Years
Max age
65 Years
Healthy volunteers
No
Inclusion Criteria: * Diagnosed with Post-COVID-19 Syndrome * Aged between 18-65 years * Able to read and understand Turkish * Voluntary participation * Classified as Post-Covid Functional Status Scale (PCFS) grade 2-3 * Clinically stable condition * No uncontrolled comorbidities (e.g., hypertension, diabetes under control) * No orthopedic or neurological conditions affecting exercise testing Exclusion Criteria: * Recent myocardial infarction or pulmonary embolism * Severe uncontrolled chronic diseases * Neurological or orthopedic conditions limiting mobility * Psychiatric or neurological disorders affecting cooperation or test compliance * Inability to complete assessments

Primary outcome measure(s)

  • Respiratory Muscle Strength — Time Frame: Day 1
    Maximal inspiratory pressure (MIP), maximal expiratory pressure (MEP) values will be recorded with mouth pressure device.
  • Dynamic respiratory muscle strength — Time Frame: Day 1
    Respiratory muscle strength index (S index) will be assessed using a portable POWERbreathe K5 device.
  • Respiratory muscle endurance — Time Frame: Day 1
    Respiratory muscle endurance test at constant threshold load will be used.

Trial sites (1)

FacilityCityRegionStatus
Hacettepe University Faculty of Physical Therapy and Rehabilitation Ankara Altindağ Recruiting

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Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07545499 on ClinicalTrials.gov ↗ ← All trials in Turkey