Effect of Video Game-Based Breathing Exercises on Respiratory Dysfunction in ACOS

Condition(s) studied

Investigational drug(s) / intervention(s)

Video game-based breathing exercises: İndividuals will be enrolled in the video game-based breathing exercise program. Participants in the study group will undergo the "Breathing Games" exercise program twice a week for 8 weeks, with each session lasting approximately 50 minutes. This video game-based breathing exercise program includes warm-up, cool-down, and five breathing games designed for the target patients.From the second week onward, posture exercises combined with the breathing games will be added.Thus, the exercise program will consist of a warm-up phase lasting approximately 10 minutes, including breathing control, stretching exercises, and rest; 25-30 minutes of five breathing games combined with posture exercises; followed by a cool-down phase of about 10 minutes with breathing control, stretching exercises, and rest.Additionally, participants will be provided with a home exercise program to be performed twice daily for 30 minutes, three days a week, over 8 weeks.

Group 2:Telerehabilitation-based breathing exercises: A telerehabilitation-based breathing exercise program will be administered to the control group with a frequency and duration similar to those of the intervention group (2 days per week, 8 weeks, 45-50 minutes/session). Session duration, total exercise time, home program, and interaction with the physiotherapist are planned similarly in both groups, aiming for the primary difference between groups to be solely the mode of delivery. In the control group, the level of interaction will be maintained by providing visual cues and real-time feedback during exercises. The telerehabilitation intervention will be conducted via the WhatsApp application on the patient's device. In addition, individuals will be prescribed a home exercise program to be performed 3 days a week, twice daily for 30 minutes, over the course of 8 weeks.

Study summary

Asthma and COPD are significant respiratory diseases that can coexist, referred to as Asthma-COPD Overlap Syndrome (ACOS). Patients with ACOS experience more severe clinical outcomes, including rapid decline in lung function, increased symptom burden, and reduced quality of life. Pulmonary rehabilitation-particularly breathing exercises-is a core non-pharmacological intervention recommended for this patient group. In recent years, video game-based applications have emerged as innovative tools that enhance motivation and participation in exercise programs. However, studies investigating the effects of video game-based breathing exercises in ACOS patients are extremely limited. Additionally, although dysfunctional breathing patterns are common in this group, few studies have addressed targeted interventions. The objective of the present study is to evaluate the effects of video game-based breathing exercises on dysfunctional breathing in ACOS patients.

Eligibility

Primary outcome measure(s)

• Capnography — All assessments will be performed on the participants at the first session and repeated after 8 weeks.
  It will be used to evaluate whether ventilation is adequate and if the breathing pattern is appropriate. It is a monitoring device that continuously records the concentration of CO₂ in the exhaled gases during respiration graphically (in mmHg), providing information about the patient's respiratory rate per minute and the amount of CO₂ exhaled in each breath. It measures the partial pressure of CO₂ in the exhaled air, referred to as end-tidal CO₂ (ETCO₂), which is a reliable and time-sensitive clinical measurement of respiratory function. ETCO₂ shows good concurrent validity when compared directly with blood measurements. A value of 35 mmHg or below is commonly used as a cutoff point to define hypocapnia.

Trial sites (1)

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