Does Cognitive Status Affect Pulmonary Rehabilitation Gains?

Condition(s) studied

Investigational drug(s) / intervention(s)

Pulmonary rehabilitation: Exercise program includes aerobic (walking band, bicycle, arm ergometer) and strengthening (with free weights) components.

Study summary

Pulmonary rehabilitation program with aerobic and strengthening trainings for 3 months will be applied to the candidates for lung transplantation. The program will be designed to be 2 days supervised weekly and 3 day home program. After completion of the program, patients will be divided into two groups according to their cognitive status (Group 1: those with poor cognition; Group 2: those with good cognition). The PR gains of the groups will be compared.

Eligibility

Primary outcome measure(s)

• Change from Baseline the 6 minutes walk distance at 3 months. — 3 months
  The test was conducted in a 30-m corridor in line with American Thoracic Society (ATS) guidelines. Patients were told that they should walk as fast as they can walk in 6 minutes time.
• Change from Baseline the Montreal Cognitive Assessment (MoCA) test score at 3 months. — 3 months
  It was designed to detect mild cognitive impairment.Thirty items assessing multiple cognitive domains are contained in the MoCA: short-term memory (5 points); visuospatial abilities via clock drawing (3 points), and a cube copy task (1 point); executive functioning via an adaptation of Trail Making Test Part B (1 point), phonemic fluency (1 point), and verbal abstraction (2 points); attention, concentration, and working memory via target detection (1 point), serial subtraction (3 points), digits forward (1 point), and digits backward (1 point); language via confrontation naming with low-familiarity animals (3 points), and repetition of complex sentences (2 points); and orientation to time and place (6 points). The MoCA is scored by obtaining an item total and the authors recommend a clinical cutoff score of 23.

Trial sites (1)

More Istanbul Medipol University Hospital trials in Turkey

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