Ireland
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Starting soon Observational

Cranial Nerve Functions in Behçet's Disease and Their Relationship With Clinical Parameters

NCT07135063 · tracked via the Priya Life Science Turkey tracker
Phase
Observational
Started
2025-10
Last updated
2025-08-21

Condition(s) studied

Behcet DiseaseCranial Nerve Disorder

Study summary

The goal of this study is to find out whether cranial nerves are affected in people with Behçet's Disease (BD), and how this might relate to other disease features. Cranial nerves control important functions such as vision, facial movement, hearing, swallowing, and balance.

The main questions this study will address are:

* Do people with BD have changes in cranial nerve function compared to healthy individuals?
* Are these changes linked to disease duration, symptoms, or lab results?

Participants will:

* Answer questions about their medical history and BD symptoms
* Complete questionnaires on daily function, mood, and autonomic symptoms
* Have a clinical examination of all 12 cranial nerves
* Undergo non-invasive electrical tests to assess nerve function This study will not involve any medications. All procedures will be completed in one visit.

Eligibility

Sex
ALL
Min age
18 Years
Max age
75 Years
Healthy volunteers
Accepted
Inclusion Criteria: * Aged 18-75 * Diagnosed with BD according to ACR/EULAR 2013 criteria (patient group) * Healthy with no relevant medical history (control group) Exclusion Criteria: * Conditions affecting CN assessment (e.g., facial trauma, surgery, radiotherapy) * Other rheumatologic or autoimmune diseases * Psychiatric disorders, alcohol/substance abuse * Pregnant women * Use of pacemakers or recent botox to masseter muscle

Primary outcome measure(s)

  • Establish the presence or absence of cranial nerve involvement in BD. — Once: Upon patient inclusion
    Upon patient inclusion EMG and clinical examination is carried out

Trial sites (1)

FacilityCityRegionStatus
Marmara Üniversitesi Tıp Fakültesi Istanbul Maltepe
Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07135063 on ClinicalTrials.gov ↗ ← All trials in Turkey