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Recruiting Not applicable

Effects of TPR and Z Techniques on Pain and Drug Leakage in Intramuscular Injections

NCT07004166 · tracked via the Priya Life Science Turkey tracker
Phase
Not applicable
Started
2025-06-15
Last updated
2025-06-04

Condition(s) studied

Muscle PainInjection Site Pain

Investigational drug(s) / intervention(s)

Z-track methodTPR method

Z-track method: Z-track method, the skin will be pulled laterally by 2.5-3.5 cm before needle insertion at a 90-degree angle. After aspiration and injection, the needle will be withdrawn and the skin released immediately.

TPR method: TPR method, while the needle is inserted at a 90-degree angle, deep pressure will be applied to the muscle, then rapidly released to create a snapping motion that facilitates the injection. This technique relies on rapid muscle relaxation rather than needle movement by the dominant hand.

Study summary

This randomized, triple-blind clinical trial compares the effectiveness of Z-track and TPR (traction-pressure-release) techniques in reducing pain and medication leakage during ventrogluteal intramuscular injections. Pain is measured using VAS, and leakage is assessed with a millimeter scale. The study aims to identify a more efficient, less painful injection method.

Eligibility

Sex
ALL
Min age
18 Years
Max age
40 Years
Healthy volunteers
Accepted
Inclusion Criteria: * Aged 16-40 * Prescribed diclofenac sodium * No communication impairments * Healthy ventrogluteal muscles without sensory issues Exclusion Criteria: * Wounds, redness, bruising, tenderness, or stiffness at the injection site * Injection in the past 2 weeks * Neuropathy or other medical conditions * BMI below 15 or above 35

Primary outcome measure(s)

  • Pain with visual analog scale — Within 5 minutes after intramuscular injection
    Pain intensity measured with the Visual Analog Scale (VAS), ranging from 0 (no pain) to 10 (worst possible pain). Higher scores indicate greater pain.

Trial sites (2)

FacilityCityRegionStatus
Sivas Numune Hospital Sivas Turkey (Türkiye) Recruiting
Sivas State Hospital Sivas Turkey (Türkiye) Recruiting
Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07004166 on ClinicalTrials.gov ↗ ← All trials in Turkey