Clinical Trials in Sweden / NCT07500974
Recruiting
Phase 2
Efficacy of L-menthol on Breathlessness in Asthma
NCT07500974 · tracked via the Priya Life Science Sweden tracker
Condition(s) studied
Asthma
Investigational drug(s) / intervention(s)
L-menthol →Placebo
L-menthol: (Sigma-Aldrich, St. Louis, US)
Placebo: Strawberry scent (Sigma-Aldrich, St. Louis, US)
Study summary
The purpose of this study is to assess the effect of L-menthol on breathlessness and exercise capacity in patients with Asthma.
Eligibility
Inclusion Criteria:
* the subject has given written consent to participate in the study
* physician diagnosis of Asthma according to international guidelines
* mMRC (modified Medical Research Council) score of 1 or above
* age 18 years or older
* able to cycle
* able to understand and talk Swedish to participate in the study procedures, as judged by the Investigators.
Exclusion Criteria:
* resting peripheral oxygen saturation (SpO2) \< 92%
* hospitalization or clinical instability during the last four weeks
* treatment with supplementary oxygen at rest or during exercise
* contraindication to exercise testing in accordance with clinical practice guidelines
* expected survival shorter than six months as judged by the Investigator
* medical conditions including congestive heart failure, acute coronary artery disease, neuromuscular diseases, severe psychiatric illness, and olfaction disorder.
Primary outcome measure(s)
- Breathlessness intensity — During submaximal test, at isotime during day 2 and day 3.
The difference between treatment conditions in dyspnea intensity at iso-time. The Borg's modified 0-10 category ratio scale (Borg CR10) will be used, where 0 represents no perceived breathlessness at all, and 10 represents maximum breathlessness intensity ever experienced.
Trial sites (2)
| Facility | City | Region | Status |
|---|---|---|---|
| Blekinge Institute of Technology | Karlskrona | Blekinge County | Not Yet Recruiting |
| Lund University hospital and Region Skåne | Lund | Sweden | Recruiting |
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Official registry record
This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
View NCT07500974 on ClinicalTrials.gov ↗ ← All trials in Sweden