US acquisitions: US acquisition from two anatomical regions i.e., the non-dominant arm and the neck.
Study summary
This is a single-center observational study aimed at setting up and testing new ultrasound vascular imaging protocols, conducted exclusively for research purposes. The study will perform US examinations in 60 subjects. The subjects enrolled in the study will be examined the first time and will then provide consent to be examined again in the future if needed.
The primary aim of this study is to set-up and test new advanced US protocol for the arm and cerebral blood vessels
The secondary objectives will be:
* Define ranges of normality/reference values of US-based parameters to be compared with pathological values.
* Evaluate the repeatability and reproducibility of the acquired US measurements.
* Evaluate the correlation between age and the acquired US measurements.
* Evaluate the correlation between gender and the acquired US measurements.
Eligibility
Sex
ALL
Min age
18 Years
Max age
75 Years
Healthy volunteers
Accepted
Inclusion Criteria:
* Provision of informed consent prior to any study specific procedures
* Female and/or male aged between 18 and 75 years
* No previous history of kidney or cerebral disease and no pathologies that might have affected the vascular system
Exclusion Criteria:
* Previous history of kidney or cerebral disease or pathologies that might have affected the vascular system
* Legal incapacity, limited legal capacity, intellectual disability, uncooperative attitude or any other evidence that the subject will not be able to understand the study aims and procedures
Primary outcome measure(s)
Non-dominant arm US acquisitions — US acquisition at enrollment Diameter of the radial artery in the middle forearm, brachial artery over the elbow, ulnar artery in the middle forearm and Cephalic vein in the middle forearm (mm)
Non-dominant arm US acquisitions — US acquisition at enrollment Flow volume of the radial artery in the middle forearm, brachial artery over the elbow, ulnar artery in the middle forearm (ml/min)
Non-dominant arm US acquisitions — US acquisition at enrollment Thickness of the radial artery and cephalic vein wall (mm)
Non-dominant arm US acquisitions — US acquisition at enrollment Stiffness of the radial artery and cephalic vein wall (%)
Non-dominant arm US acquisitions — US acquisition at enrollment Time averaged velocity (TAV) of the radial artery in the middle forearm, brachial artery over the elbow and ulnar artery in the middle forearm (cm/s)
Neck carotid (right and left) US acquisitions — US acquisition at enrollment Diameter of the common carotid artery, internal carotid artery, external carotid artery and vertebral arteries (mm)
Neck carotid (right and left) US acquisitions — US acquisition at enrollment Flow volume of the common carotid artery, internal carotid artery, external carotid artery and vertebral arteries (ml/min)
Neck carotid (right and left) US acquisitions — US acquisition at enrollment Thickness of the wall of the common carotid (mm)
Neck carotid (right and left) US acquisitions — US acquisition at enrollment Stiffness of the wall of the common carotid (%)
Neck carotid (right and left) US acquisitions — US acquisition at enrollment Time averaged velocity (TAV) of the common carotid artery, internal carotid artery, external carotid artery and vertebral arteries (cm/s)
Trial sites (1)
Facility
City
Region
Status
Clinical Research Centre for Rare Diseases Aldo e Cele Daccò
Ranica
BG
Recruiting
More Mario Negri Institute for Pharmacological Research trials in Italy
This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
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