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Trackers› Clinical trials› Bad Nauheim
Clinical trial register · Germany

Clinical Trials in Bad Nauheim, 2026

Every study on the ClinicalTrials.gov registry that lists a site in Germany and is open, about to open, active-but-closed, or enrolling by invitation. Filter it, cite it, and take it away as a file.

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Source: ClinicalTrials.gov, U.S. National Library of Medicine. Complete coverage — all 5051 matching records held by the registry are in this view. Synced 26 Sep 2026, 19:51 UTC
5051
Studies in scope
all four open statuses
2882
Recruiting now
open to new participants
988
Lead sponsors
across recruiting studies
Top sites
Berlin 1584 Hamburg 889 Essen 760 Dresden 707 Heidelberg 627
Narrow the registerReset
Recruitment status
Phase
Lead sponsor
Abbott Medical Devices4 Heart and Brain Research Group, Germany3 Corvia Medical3 AstraZeneca3 Hoffmann-La Roche2
Site location
Berlin1584 Hamburg889 Essen760 Dresden707 Heidelberg627
All 635 locations
Target enrolment
to

Trials with a site in Bad Nauheim

52 of 5051 studies
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Status
Study
Lead sponsor
Phase
Enrol
Sites in Germany
Start
Not yet open
NeoAdjuvant Therapy Comparing Sacituzumab Govitecan+Pembrolizumab vs. SoC Chemotherapy in Clinical Stage II-III, Triple-negative Early Breast Cancer
NCT07178730Breast Cancer, Triple-negative Breast Cancer
DrugsSacituzumab Govitecan·Keytruda·Pembrolizumab
Women's Cancer Study Group GmbH
Phase 3
765
Heilbronn, Weinheim, Augsburg, München, Regensburg, Würzburg, Cottbus, Bad Nauheim
2026-08-30
Recruiting
BIO|STREAM.CSP Study
NCT07393009Cardiac Pacing, Cardiac Pacemaker, Implantable Cardioverter Defibrillator, Cardiac Resynchronization Therapy Devices
Biotronik SE & Co. KG
Observational
1,000
Bad Krozingen, Bad Nauheim, Bad Oeynhausen, Cologne, Osnabrück
2026-05-25
Recruiting
BIOTRONIK Investigation of the LivIQ Leadless Pacemaker System
NCT07118358Leadless Pacemaker, Bradycardia, AV Block, Cardiac Rhythm Disorder
Biotronik, Inc.
Not applicable
325
Bad Nauheim, Bad Oeynhausen, Düsseldorf
2026-03-16
Recruiting
Decreasing Stress Via Virtual Reality and Binaural Beats in Non-Clinical Adults
NCT07387107Stress, Relaxation, Virtual Reality, Binaural Beats
Heart and Brain Research Group, Germany
Not applicable
52
Bad Nauheim
2026-03-05
Recruiting
LEVEL-2: LEVosimendan to Improve Exercise Limitation in Patients With PH-HFpEF-2
NCT07288398Pulmonary Hypertension Associated With HFpEF
DrugTNX-103
Tenax Therapeutics, Inc.
Phase 3
540
Bad Bevensen, Bad Nauheim, Berlin, Dresden, Hamburg, Jena, Mainz
2026-03-03
Recruiting
Chemotherapy De-escalation in HR +, HER2-, Intermediate-risk Early Breast Cancer Treated With Adjuvant Ribociclib
NCT07237256Breast Cancer
UNICANCER
Phase 3
3,902
Aachen, Augsburg, Bad Nauheim, Berlin, Bremen, Cottbus, Dresden, Düsseldorf
2025-12-18
Recruiting
Effects of Continued Administration of Empagliflozin in Patients With Heart Failure on Active SGLT2 Inhibitor Treatment Admitted for Acute Decompensated Heart Failure
NCT07038356Acute Decompensated Heart Failure (ADHF)
DrugDapagliflozin
Christian Schulze
Phase 3
536
Jena, Bad Nauheim, Berlin, Bonn, Dresden, Göttingen, Halle, Leipzig
2025-12-08
Recruiting
Impact of BPA in CTEPH on Cardiac and Pulmonary Physiology Assessed by CMR-derived 4D Flow Haemodynamics
NCT07299227CTEPH
Kerckhoff Klinik
Observational
60
Bad Nauheim
2025-09-01
Recruiting
Left Bundle Branch Area Pacing (LBBAP) PMCF Study
NCT07217392Bradycardia, Right Ventricular Pacing, Heart Failure, Atrial Fibrillation (AF)
Abbott Medical Devices
Not applicable
200
Bad Nauheim
2025-07-24
Not yet open
CMR-derived Quantitative Perfusion for Prediction of FFR
NCT07018778Chronic Coronary Syndrome
Kerckhoff Klinik
Observational
200
Bad Nauheim
2025-07-01
Recruiting
NIS to Examine the Effectiveness and Safety of Durvalumab and Olaparib in Patients With Endometrial Cancer (DUOLife)
NCT06890273Endometrial Cancer
AstraZeneca
Observational
150
Amberg, Bad Nauheim, Bautzen, Berlin, Bielefeld, Bonn, Borna, Bottrop
2025-05-20
Recruiting
Cyclosporine In Takotsubo Syndrome
NCT05946772Takotsubo Cardiomyopathy
DrugCyclosporine A
University Hospital Heidelberg
Phase 2
204
Bad Nauheim, Berlin, Bonn, Cologne, Dresden, Düsseldorf, Essen, Frankfurt
2025-02-01
Recruiting
Study With Omecamtiv Mecarbil (CK-1827452) to Treat Chronic Heart Failure With Severely Reduced Ejection Fraction
NCT06736574Heart Failure, Heart Failure With Reduced Ejection Fraction
Cytokinetics
Phase 3
1,800
Heidelberg, München, Würzburg, Hamburg, Erfurt, Jena, Mainz, Bad Nauheim
2024-12-19
Recruiting
REdo Transcatheter Aortic VALVE Implantation for the Management of Transcatheter Aortic Valve Failure
NCT06557798Aortic Valve Stenosis
The Leeds Teaching Hospitals NHS Trust
Observational
550
Bad Nauheim, Bad Oeynhausen, Berlin, Cologne, Dortmund, Dresden, Düsseldorf, Frankfurt
2024-12-12
Recruiting
Real World European Investigation of Safety and Clinical Efficacy of the EVOQUE System (TRISCEND III EU)
NCT06569602Tricuspid Valve Regurgitation, Heart Valve Diseases, Cardiovascular Diseases
Edwards Lifesciences
Observational
500
Bad Berka, Bad Nauheim, Bad Neustadt an der Saale, Bad Oeynhausen, Berlin, Bonn, Dortmund, Essen
2024-10-01
Recruiting
Prospective WCD Post CABG Registry (CABG Registry)
NCT06570902Cardiomyopathy Ischemic, Cardiomyopathies, Cardiovascular Diseases, Heart Disease, Ischemic
Zoll Medical Corporation
Observational
910
Bad Nauheim, Hanover, Cottbus, Halle
2024-09-23
Recruiting
Impact of Beta-blocker on Outcome Among Patients Undergoing Transcatheter Aortic Valve Replacement (B-TAVR)
NCT06472934Aortic Stenosis
University Hospital, Basel, Switzerland
Not applicable
498
Bad Krozingen, Bad Nauheim, Bad Oeynhausen, Giessen, Kiel
2024-07-04
Recruiting
A Study to Investigate the Efficacy and Safety of Anifrolumab Administered as Subcutaneous Injection and Added to Standard of Care Compared With Placebo Added to Standard of Care in Adult Participants With Idiopathic Inflammatory Myopathies (Polymyositis and Dermatomyositis)
NCT06455449Polymyositis, Dermatomyositis
AstraZeneca
Phase 3
240
Bad Nauheim, Berlin, Bonn, Freiburg im Breisgau, Herne, München, Tübingen
2024-06-20
Recruiting
Association Between Biomarkers and Kidney Function Decline in Pulmonary Hypertension
NCT06409624Pulmonary Hypertension, Chronic Kidney Disease
University of Giessen
Observational
400
Bad Nauheim, Giessen
2024-05-31
Active, closed
The Effect of Retatrutide Once Weekly on Cardiovascular Outcomes and Kidney Outcomes in Adults Living With Obesity (TRIUMPH-Outcomes)
NCT06383390Atherosclerotic Cardiovascular Disease (ASCVD), Chronic Kidney Disease (CKD)
DrugRetatrutide
Eli Lilly and Company
Phase 3
10,000
Bad Nauheim, Bad Oeynhausen, Berlin, Bremen, Dortmund, Dresden, Elsterwerda, Essen
2024-04-30
Recruiting
Study to Evaluate the Effect of Balcinrenone/Dapagliflozin in Patients With Heart Failure and Impaired Kidney Function
NCT06307652Heart Failure and Impaired Kidney Function
AstraZeneca
Phase 3
3,850
Bad Nauheim, Bechhofen, Berlin, Bernau bei Berlin, Chemnitz, Coburg, Dresden, Elsterwerda
2024-04-12
By invitation
ENVISION IDE Trial: Safety and Effectiveness of NAVITOR in Transcatheter Aortic Valve Implantation
NCT05932615Aortic Valve Stenosis, Heart Valve Diseases, Aortic Valve Disease, Heart Disease Structural Disorder
Abbott Medical Devices
Not applicable
1,500
Dortmund, Bad Nauheim, Cologne, Frankfurt, Kiel, München, Ulm
2024-03-15
Recruiting
Prevention Of Sudden Cardiac Death After Myocardial Infarction by Defibrillator Implantation
NCT05665608Sudden Cardiac Death, Myocardial Infarction
Charite University, Berlin, Germany
Not applicable
3,595
Ahaus, Aue, Bad Nauheim, Bad Oeynhausen, Bad Segeberg, Berlin, Bielefeld, Coburg
2023-11-16
Recruiting
Complete Revascularization Versus Culprit Lesion Only PCI in NSTEMI
NCT05786131Non-ST-elevation Myocardial Infarction, Multivessel Coronary Artery Disease
Leipzig Heart Science gGmbH
Not applicable
3,390
Bad Berka, Bad Krozingen, Bad Nauheim, Bad Oeynhausen, Berlin, Bielefeld, Bochum, Bremen
2023-10-27
Active, closed
Enlicitide Decanoate (MK-0616 Oral PCSK9 Inhibitor) Cardiovascular Outcomes Study (MK-0616-015) CORALreef Outcomes
NCT06008756Arteriosclerosis, Hypercholesterolaemia
DrugEnlicitide Decanoate
Merck Sharp & Dohme LLC
Phase 3
14,550
Bad Friedrichshall, Heidelberg, Mannheim, Nuremberg, Wallerfing, Bad Nauheim, Frankfurt am Main, Hanover
2023-10-09
Recruiting
The ReTAVI Prospective Observational Registry
NCT05601453Structural Valve Deterioration, Structural Valve Degeneration, Symptomatic Patients Who Have Had Transcatheter Heart Valve (THV) Failure, Prosthetic Valve Malfunction
Institut für Pharmakologie und Präventive Medizin
Observational
250
Bad Krozingen, Bad Nauheim, Bad Oeynhausen, Berlin, Bochum, Düsseldorf, Essen, Munich
2023-09-05
Recruiting
Decreasing Preoperative Stress to Prevent Postoperative Delirium and Postoperative Cognitive Decline in Cardiac Surgical Patients.
NCT05036538Preoperative Stress, Postoperative Cognitive Dysfunction, Postoperative Delirium
Heart and Brain Research Group, Germany
Not applicable
125
Bad Nauheim
2023-07-27
Active, closed
TrEatment Approach in the Multimodal Era Registry
NCT05629052Chronic Thromboembolic Pulmonary Hypertension, CTEPH
International CTEPH Association
Observational
1,000
Bad Nauheim
2023-04-12
Active, closed
RESPONDER-HF Trial
NCT05425459Heart Failure, Heart Failure, Diastolic
Corvia Medical
Not applicable
750
Bad Krozingen, Bad Nauheim, Berlin, Cologne, Dresden, Düsseldorf, Freiburg im Breisgau, Göttingen
2022-11-17
Active, closed
A Study to Evaluate the Efficacy and Safety of Giredestrant in Combination With Phesgo (Pertuzumab, Trastuzumab, and Hyaluronidase-zzxf) Versus Phesgo in Participants With Locally Advanced or Metastatic Breast Cancer (heredERA Breast Cancer)
NCT05296798Locally Advanced or Metastatic Breast Cancer
DrugsPhesgo·Giredestrant·Docetaxel·Paclitaxel
Hoffmann-La Roche
Phase 3
922
Bad Nauheim, Bamberg, Essen, Freiburg im Breisgau, Heidelberg, Hildesheim, Homburg/Saar, Langen
2022-07-18
Active, closed
Phase 2 Safety and Efficacy Study of Tulisokibart (MK-7240/PRA023) in Subjects With Systemic Sclerosis Associated With Interstitial Lung Disease (SSc-ILD) (MK-7240-007)
NCT05270668Diffuse Cutaneous Systemic Sclerosis, Interstitial Lung Disease
DrugTulisokibart
Prometheus Biosciences, Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)
Phase 2
154
Freiburg im Breisgau, Bad Nauheim, Hohenfelde B Bad Doberan, Cologne
2022-03-29
Active, closed
Percutaneous or Surgical Repair In Mitral Prolapse And Regurgitation for ≥60 Year-olds (PRIMARY)
NCT05051033Mitral Valve Regurgitation
Annetine Gelijns
Not applicable
450
Cologne, Bad Oeynhausen, Bad Nauheim, Bad Rothenfelde, Berlin, Frankfurt, Freiburg im Breisgau, Hamburg
2022-02-21
Active, closed
From the Emergency Department Directly to Ablation of Atrial Fibrillation Study
NCT05294445Atrial Fibrillation (AF)
Asklepios proresearch
Not applicable
350
Bad Nauheim, Berlin, Cologne, Düsseldorf, Frankfurt, Giessen, Hamburg, Hamburg-Nord
2021-12-15
Active, closed
Evaluation of TAVR Using the NAVITOR Valve in a Global Investigation
NCT04788888Symptomatic Severe Aortic Stenosis
Abbott Medical Devices
Not applicable
434
Bad Nauheim, Berlin, Dortmund, Dresden, Frankfurt, Hamburg, Leipzig, München
2021-07-13
Recruiting
CORCYM Mitral, Aortic aNd Tricuspid Post-maRket Study in a reAl-world Setting
NCT05002543Cardiac Valve Disease
Corcym S.r.l
Observational
2,150
Augsburg, Bad Nauheim, Berlin, Dresden, Essen, Magdeburg, Nuremberg, Oldenburg
2021-06-29
Active, closed
A Study Evaluating the Efficacy and Safety of Adjuvant Atezolizumab or Placebo and Trastuzumab Emtansine for Participants With HER2-Positive Breast Cancer at High Risk of Recurrence Following Preoperative Therapy
NCT04873362Breast Cancer
DrugsTrastuzumab emtansine·Herceptin·Tecentriq·Trastuzumab
Hoffmann-La Roche
Phase 3
1,188
Augsburg, Bad Nauheim, Berlin, Bonn, Bottrop, Dessau, Düsseldorf, Erfurt
2021-05-04
Active, closed
ABLATE Versus PACE: PVI or AV Node Ablation and PM Implantation for Elderly Patients With Persistent AF
NCT04906668Atrial Fibrillation
St. Josefs-Hospital Wiesbaden GmbH
Not applicable
196
Bad Nauheim, Berlin, Essen, Frankfurt, Fürth, Hagen, Hamburg, Kaiserslautern
2021-05-01
Active, closed
The Elixir Bioadaptor vs. The Onyx Stent in De Novo Native Coronary Arteries
NCT04192747Coronary Artery Disease, Coronary Artery Stenosis, Coronary Disease, Coronary Stenosis
Elixir Medical Corporation
Not applicable
445
Bad Nauheim, Bad Segeberg, Coburg, Dortmund, Erlangen, Essen, Frankfurt, Giessen
2020-12-16
Active, closed
ACURATE neo2™ Post Market Clinical Follow up Study
NCT04655248Aortic Valve Stenosis, Aortic Valve Calcification, Aortic Diseases
Boston Scientific Corporation
Observational
250
Bad Nauheim, Bad Oeynhausen, Dortmund, Regensburg
2020-12-16
Recruiting
LANDMARK Trial: a Randomised Controlled Trial of Myval THV
NCT04275726Aortic Valve Stenosis
Meril Life Sciences Pvt. Ltd.
Not applicable
988
Bad Nauheim, Leipzig, Bad Krozingen, Braunschweig, Dresden, Hamburg, Regensburg
2020-11-04
Active, closed
Pulmonary Artery Sensor System Pressure Monitoring to Improve Heart Failure (HF) Outcomes
NCT04398654Heart Failure
IHF GmbH - Institut für Herzinfarktforschung
Not applicable
554
Bad Friedrichshall, Bad Nauheim, Bad Oeynhausen, Berlin, Bielefeld, Bonn, Coburg, Dortmund
2020-10-02
Active, closed
Optimal Timing of Transcatheter Aortic Valve Implantation and Percutaneous Coronary Intervention - The TAVI PCI Trial
NCT04310046Aortic Stenosis, Coronary Artery Disease, TAVI, PCI
University of Zurich
Not applicable
986
Bad Berka, Bad Bevensen, Bad Krozingen, Bad Nauheim, Bad Neustadt an der Saale, Bad Rothenfelde, Bad Segeberg, Berlin
2020-09-30
Recruiting
Increasing Preoperative Cognitive Reserve to Prevent Postoperative Cognitive Dysfunction in Cardiac Surgical Patients
NCT04493996Postoperative Cognitive Decline, Postoperative Delirium, Postoperative Cognitive Dysfunction
Heart and Brain Research Group, Germany
Not applicable
100
Bad Nauheim
2020-08-14
Recruiting
Anticoagulation for New-Onset Post-Operative Atrial Fibrillation After CABG
NCT04045665Atrial Fibrillation, Stroke, Bleeding
Icahn School of Medicine at Mount Sinai
Phase 3
3,200
Berlin, Göttingen, Jena, Bad Nauheim, Bad Neustadt an der Saale, Bad Oeynhausen, Bonn, Braunschweig
2019-12-13
Recruiting
Observation of Clinical Routine Care for Patients With BIOTRONIK Implantable Cardiac Monitors (ICMs)
NCT04075084Tachycardia, Atrial Fibrillation, Syncope, Bradycardia
Biotronik SE & Co. KG
Observational
1,400
Ahaus, Bad Nauheim, Bad Neustadt an der Saale, Dresden, Erfurt, Herford, Leipzig, Mitte
2019-10-28
Active, closed
SyncAV Post-Market Trial
NCT04100148Congestive Heart Failure
Abbott Medical Devices
Not applicable
1,686
Heidelberg, Dresden, Bad Nauheim
2019-10-03
Active, closed
THE ALIGN-AR EFS TRIAL: JenaValve Pericardial TAVR Aortic Regurgitation Study
NCT02732704Aortic Regurgitation
JenaValve Technology, Inc.
Not applicable
100
Bad Nauheim, Bad Oeynhausen, Berlin, Bonn, Cologne, Frankfurt, Hamburg
2018-04-20
Active, closed
REDUCE LAP-HF TRIAL II
NCT03088033Heart Failure
Corvia Medical
Not applicable
608
Bad Nauheim, Berlin, Düsseldorf, Freiburg im Breisgau, Göttingen, Hamburg, Heidelberg, Leipzig
2017-06-01
Active, closed
Randomized Trial of TAVI vs. SAVR in Patients With Severe Aortic Valve Stenosis at Low to Intermediate Risk of Mortality
NCT03112980Aortic Valve Stenosis
Universitätsklinikum Hamburg-Eppendorf
Not applicable
1,414
Hamburg, Aachen, Bad Krozingen, Bad Nauheim, Bad Neustadt an der Saale, Bad Oeynhausen, Berlin, Bernau
2017-05-10
Active, closed
REDUCE LAP-HF III Corvia Protocol 1701
NCT03191656Heart Failure
Corvia Medical
Observational
500
Bad Nauheim, Bad Oeynhausen, Bad Segeberg, Berlin, Chemnitz, Cologne, Detmold, Dresden
2017-03-12
Active, closed
International T1 Multicenter Outcome Study
NCT03749343Heart Failure, Cardiomyopathies, Inflammatory Disease, Coronary Artery Disease
Johann Wolfgang Goethe University Hospital
Observational
8,000
Bad Nauheim, Frankfurt am Main
2016-03-01
Active, closed
REDUCER-I: An Observational Study of the Neovasc Reducer™ System
NCT02710435Angina Pectoris, Angina Pectoris, Stable, Chronic Stable Angina
Shockwave Medical, Inc.
Observational
400
Bad Nauheim, Dresden, Essen, Freiburg im Breisgau, Giessen, Hamburg
2016-03
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Cite this view

Priya Life Science (2026). Clinical trial register: studies with a German investigative site, filtered. Derived from ClinicalTrials.gov. Retrieved 1 October 2026. https://priyalifescience.com/clinical-trials-germany/city/bad-nauheim

Query this register directly
GET /api/trials?country=in&status=recruiting&format=json Try it now →

About this register

This register is built from ClinicalTrials.gov, the trial registry run by the U.S. National Library of Medicine. It includes every study on the registry that lists at least one investigative site in Germany and is recruiting, not yet recruiting, active but no longer recruiting, or enrolling by invitation: 5,051 studies in total at the last sync on 26 Sep 2026, 19:51 UTC. The full list can be downloaded as CSV or queried as JSON through the register API.

This page shows the 52 of those studies with a site in Bad Nauheim.

How many clinical trials are recruiting in Bad Nauheim?

27 of the 52 studies on this page are recruiting new participants as of the 26 Sep 2026, 19:51 UTC sync. A further 2 have not yet opened recruitment, 22 are active but closed to new participants, and 1 are enrolling by invitation only. Eligibility for any study is decided by its study team.

Summary by phase

Studies by phase (Bad Nauheim), 52 studies
PhaseStudiesRecruitingShare
Not applicable22942.3%
Observational161030.8%
Phase 312723.1%
Phase 2213.8%

Most active sponsors

Lead sponsors with the most studies (Bad Nauheim)
Lead sponsorStudiesRecruiting
Abbott Medical Devices41
AstraZeneca33
Corvia Medical30
Heart and Brain Research Group, Germany33
Biotronik SE & Co. KG22
Hoffmann-La Roche20
Kerckhoff Klinik21
Annetine Gelijns10
Asklepios proresearch10
Biotronik, Inc.11
Listing here is informational and not medical advice; eligibility is determined by each study team. See also the Ireland, UK, EU, USA and China registers.