Patients with CTEPH referred for evaluation and conduction of BPA undergo standard of care diagnostic tests and treatment. This includes conventional echocardiographic, RHC and non-invasive (CT/CMR) or invasive (coronary angiography) coronary artery disease work-up. BPA will be conducted in generally 5 to 6 consecutive sessions. CMR will be performed prior to first and following the last intervention. Patient recruitment will be performed within 3 years, that is the last BPA session of the last patient in will have been performed at 3 years time.
Eligibility
Sex
ALL
Min age
18 Years
Max age
99 Years
Healthy volunteers
No
Inclusion Criteria:
* Patient referred to BPA
* clinical indication for CMR
* capability to give informed consent
Exclusion Criteria:
* general: non-compliance, \<18 years of age, pregnancy
* contraindications for CMR (non-CMR compatible device, chronic kidney disease (eGFR \<30ml/min), allergies (medications)
Primary outcome measure(s)
Impact of BPA on cardio-pulmonary vascular physiology — 1 year 1a) Changes in right cardiac function (RV EF %)
Impact of BPA on cardio-pulmonary vascular physiology — 1 year 1b) Changes in cardiac function (RV GLS%)
Impact of BPA on cardio-pulmonary vascular physiology — 1 year 2a) Changes in pulmonary artery flow (peak flow m/s)
Impact of BPA on cardio-pulmonary vascular physiology — 1 year 2b) Changes in pulmonary artery flow (mean flow m/s)
Impact of BPA on cardio-pulmonary vascular physiology — 1 year 2c) Changes in pulmonary artery flow (pulse wave velocity m/s)
This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
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