Patients will undergo quantitative perfusion assessment in cardiovascular magnetic resonance imaging (dual bolus or dual sequence approach) as well as invasive coronary angiography for assessment of fractional flow reserve (FFR) including assessment of coronary flow reserve (CFR) and microcirculatory resistance (IMR).
Eligibility
Sex
ALL
Min age
18 Years
Max age
99 Years
Healthy volunteers
No
Inclusion Criteria:
* clinical indication for vasodilatator CMR or invasive coronar angiography
* capability to give informed consent
Exclusion Criteria:
* general: non-compliance, \<18 years of age, pregnancy
* contraindications for CMR (non-CMR compatible device, chronic kidney disease (eGFR \<30ml/min), allergies (medications)
Primary outcome measure(s)
Quantitative Perfusion — assessment of CMR and invasive data within 24hours Correlation of myocardial blood flow and perfusion reserve in CMR with invasively dervived fractional flow reserve (FFR), coronary flow reserve (CFR) and microcirculatory resistance (IMR)
Dual bolus vs dual sequence — assessment of CMR and invasive data within 24hours Compare both CMR-derived quantitative perfusion for prediction of FFR/CFR/IMR
This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
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