Ireland
--:--IST
Latest
Astellas Expands Its 330 Million Euro Tralee Biopharma Facility with a Second Aseptic Filling Line to Double Drug-Product Capacity Xeolas Pharmaceuticals Opens 158,000 Sq Ft State-of-the-Art Baldoyle Facility to Scale Specialty Medicine Manufacturing Priya Life Science Partners with Fleming for the 9th Annual Corporate Compliance & Transparency in Life Sciences Summit in Zurich Ireland Has the Capital and the Lessons: Digital Project Management Is How They Become Delivery Dunbar Pharma Brings First Plant-Derived Dronabinol API to UK Market Through IPS Pharma Leveraging Priya Life Science as a Data Tracker: The Ultimate Use Case & Career Guide The €100K Reality Check: Why a Six-Figure Pharma Salary in Ireland Feels Different Than in Switzerland or Germany Ireland's €93.8 Billion Non-EU Pharma Export Engine: 2025 Eurostat Trade Data and Economic Impact Astellas Expands Its 330 Million Euro Tralee Biopharma Facility with a Second Aseptic Filling Line to Double Drug-Product Capacity Xeolas Pharmaceuticals Opens 158,000 Sq Ft State-of-the-Art Baldoyle Facility to Scale Specialty Medicine Manufacturing Priya Life Science Partners with Fleming for the 9th Annual Corporate Compliance & Transparency in Life Sciences Summit in Zurich Ireland Has the Capital and the Lessons: Digital Project Management Is How They Become Delivery Dunbar Pharma Brings First Plant-Derived Dronabinol API to UK Market Through IPS Pharma Leveraging Priya Life Science as a Data Tracker: The Ultimate Use Case & Career Guide The €100K Reality Check: Why a Six-Figure Pharma Salary in Ireland Feels Different Than in Switzerland or Germany Ireland's €93.8 Billion Non-EU Pharma Export Engine: 2025 Eurostat Trade Data and Economic Impact
Active, not recruiting Not applicable

WB-EMS Effects on Cardiometabolic Risk Factors

NCT07406191 · tracked via the Priya Life Science Germany tracker
Phase
Not applicable
Started
2026-02-15
Last updated
2026-05-14

Condition(s) studied

HypertensionMetabolic SyndromeHypercholesterolemiaHypertriglyceridemiaOverweight and Obesity

Investigational drug(s) / intervention(s)

WB-EMSControl

WB-EMS: 12 weeks of WB-EMS, 1.5x20 min/week

Control: 12 weeks without additional intervention and without life style changes

Study summary

From the age of 50 onwards, there is a disproportionate decline in muscle strength, mass and function, which can be prevented or at least delayed by physical training. Unfortunately, many training programmes are very time-consuming and strenuous and are therefore not carried out consistently. Whole-body electromyostimulation (WB-EMS), a technology in which all major muscle groups are stimulated with an adjusted stimulation level, could be a time-effective and joint-friendly alternative.

However, there are some contraindications to the widespread use of this technology, which are particularly common in middle-aged and elderly people. For example, high blood pressure, which affects more than half of men over the age of 50 in Germany, is considered a contraindication for WB-EMS training. However, this assessment is not very reliable; at least, acute WB-EMS application does not lead to an increase in blood pressure. In addition, there are no study results available for long-term WB-EMS application in people with high blood pressure.

The present study particularly investigate whether and to what extent several weeks of WB-EMS training has an effect on resting blood pressure in people with mild blood pressure. Additionally, the effect of WB-EMS on other cardiometabolic risk factors and physical function will be addressed.

Eligibility

Sex
MALE
Min age
50 Years
Max age
70 Years
Healthy volunteers
No
Inclusion Criteria: * Grade 1 hypertension: systolic 140 and/or diastolic 90 mmHg * overweight or obese (body mass index \> 25 kg/m2) Exclusion Criteria: * blood pressure-lowering pharmacologic therapy. * WB-EMS application and regular resistance exercise training * Conditions and illnesses that preclude intensive physical exertion * Severe cardiac arrhythmia * Heart failure * acute pulmonary embolism * acute myocarditis * severe hypertension, e.g. blood pressure \> 200 mmHg systolic and/or \>110 mmHg diastolic * Contraindications for bioimpedance analysis (e.g. pacemaker) * Contraindications for WB-EMS application (e.g. acute infections/fever, epilepsy)

Primary outcome measure(s)

  • Resting blood pressure — At baseline and after 12 weeks of intervention
    Changes of mean arterial blood pressure after 10 min of rest in a sitting position as assessed by an automatic sphygmomanometer
  • Metabolic syndrome — At baseline and after 12 weeks of intervention
    Changes of the Metabolic Syndrome (MetS) as determined by the MetS-Z-Score

Trial sites (2)

FacilityCityRegionStatus
Faculty of Medicine, University of Tuebingen Erlangen Germany
Institute of Radiology, University Hospital Erlangen Erlangen Germany

More University of Erlangen-Nürnberg Medical School trials in Germany

Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07406191 on ClinicalTrials.gov ↗ ← All trials in Germany