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Clinical Trials in Germany / NCT05757960
Enrolling by invitation Not applicable

TMD-specific Physiotherapy in hEDS Patients Individuals With Hypermobile Ehlers-Danlos Syndrome

NCT05757960 · tracked via the Priya Life Science Germany tracker
Sponsor
University Hospital Muenster
Phase
Not applicable
Started
2023-02-02
Last updated
2025-04-27

Condition(s) studied

Hypermobile Ehlers-Danlos Syndrome

Investigational drug(s) / intervention(s)

Physiotherapy

Physiotherapy: Various physiotherapeutic techniques are used in three defined sessions. Before the first session, a dental examination is performed and a clinical functional status is obtained to assess the extent of temporomandibular dysfunction. The results are recorded on validated questionnaires.

Study summary

The aim of this study is to analyze the effects of strictly defined physiotherapy in patients temporomandibular dysfunction (TMD) and hypermobile Ehlers-Danlos Syndrome (hEDS). Patients will be clinically examined before starting physiotherapy and fill in the questionnaires. Subsequently, it will be followed up whether changes occur as a result of physiotherapy.

This study is a pilot study and is intended to be hypothesis generating in nature. Based on the resulting hypothesis, it will be verified by a study with a control group.

Eligibility

Sex
ALL
Min age
18 Years
Max age
—
Healthy volunteers
No
Inclusion Criteria: 1. written consent to participate in the study 2. confirmed diagnosis of hEDS (based on the diagnostic criteria of the current classification of 2017). 3. pain in the area of the masticatory muscles and/or the temporomandibular joints 4. command of the German language, both spoken and written Exclusion Criteria: 1. currently undergoing TMD-specific treatment (physiotherapy, pain therapy masticatory muscles and/or temporomandibular joint, orthopedic treatment, osteopathic treatment). 2. persons diagnosed with depression, anxiety or stress disorder 3. taking opiates 4. pregnant women 5. minors 6. persons with mental disability 7. persons who are not able to speak and write the German language 8. persons with legal representatives

Primary outcome measure(s)

  • Reduction of temporomandibular pain — Up to 3 months after the last physiotherapy intervention
    The German version of the Graded chronic pain scale (GCS) is used to measure the level of pain. The score ranges from level 0-IV, 0 representing no pain, I-II functional pain, and level III-IV dysfunctional, chronic pain.

Trial sites (1)

FacilityCityRegionStatus
Department for Prosthodontics and Biomaterials, University Hospital Münster Münster Germany

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Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT05757960 on ClinicalTrials.gov ↗ ← All trials in Germany