Biomechanical Effects of EMST® on Swallowing Function in Parkinson's Disease

NCT07606547 · tracked via the Priya Life Science Germany tracker

Sponsor

University Hospital Muenster

Phase

Not applicable

Started

2026-06

Last updated

2026-06-03

Condition(s) studied

Parkinson's Disease (PD)Dysphagia

Investigational drug(s) / intervention(s)

exspiratory muscle strength training

exspiratory muscle strength training: 5 sets of 5 breaths with EMST per day, 5 days a week for 1 month

Study summary

The aim of this non-randomized intervention study is to investigate the detailed effects of a structured four-week EMST® training program on the biomechanics of swallowing function in dysphagic Parkinson's patients. A combination of fiberoptic endoscopic evaluation of swallowing (FEES) and pharyngeal high-resolution manometry (HRM) will be employed to comprehensively evaluate the neuromuscular changes in swallowing.

Eligibility

Sex

ALL

Min age

18 Years

Max age

—

Healthy volunteers

Inclusion Criteria: * diagnosis of Parkinson's disease, * PD-related dysphagia as objectively diagnosed with FEES Exclusion Criteria: * severe dementia, not able to give consent * dysphagia related to other diagnoses

Primary outcome measure(s)

Effect on swallowing biomechanics in pharyngeal high-resolution manometry as assessed by measurement of e.g. Pharyngeal contractile Integral (PhcI) — 1 month and 3 months
metrics of pharyngeal contraction and upper esophageal sphinkter opening in high-resolution pharyngeal manometry

Trial sites (1)

Facility	City	Region	Status
University Hospital Münster, Department of Neurology	Münster	Germany	Recruiting

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Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07606547 on ClinicalTrials.gov ↗ ← All trials in Germany