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Clinical Trials in France / NCT07626593
Recruiting Not applicable

The Extraordinary Endurance of the Human Species

NCT07626593 · tracked via the Priya Life Science France tracker
Sponsor
Centre Hospitalier Universitaire de Saint Etienne
Phase
Not applicable
Started
2026-02-03
Last updated
2026-06-04

Condition(s) studied

Healthy Volunteers

Investigational drug(s) / intervention(s)

Intensive training

Intensive training: participants will follow individualized coaching: starting at 5-6 hours per week and progressing to 7-10 hours (rarely 15 hours) per week before mountain ultra marathon

Study summary

We hypothesize, based on field and scientific data, that setting a very ambitious goal such as completing a mountain ultra-marathon could motivate sedentary and inactive individuals not only to begin training but also to follow a progressive yet extremely ambitious program that has not yet been studied comprehensively. Indeed, the effects of intense and prolonged endurance training (18 months) on the health and performance of completely sedentary individuals have never been investigated exhaustively.

Eligibility

Sex
ALL
Min age
25 Years
Max age
50 Years
Healthy volunteers
Accepted
Inclusion Criteria: * Affiliation to social security. * Informed consent signed. * Male or female, aged 25-50. * Sedentary (\>6h/day sitting) and inactive (no regular training), assessed by GPAQ questionnaire. Exclusion Criteria: * Chronic joint or cardiac diseases. * Neurological disorders. * Legal protection status. * Moderate to severe depression (BDI-13 \> 7) or use of antidepressants/anxiolytics. * Use of banned substances. * Excessive alcohol or caffeine consumption. * Pregnancy. * Inability to understand or consent.

Primary outcome measure(s)

  • Transition from sedentary lifestyle to regular activity and completion of a 100 km ultra-trail — up to 18 months
    Percentage of participants who (i) become sufficiently active to be ready to start the Courmayeur-Champex-Chamonix (CCC) 100 km ultra-trail of the Ultra Trail du Mont-Blanc, and (ii) complete the 100 km CCC race.

Trial sites (1)

FacilityCityRegionStatus
CHU de Saint-Etienne Saint-Etienne France Recruiting

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Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07626593 on ClinicalTrials.gov ↗ ← All trials in France