Long-term Evaluation of Fertility Preservation Options in Women in Cancer Remission or Haematological Pathology

Condition(s) studied

Study summary

Cancer treatments, despite their increasing effectiveness, carry a significant risk of gamete toxicity.

Women of reproductive age are commonly offered fertility preservation (FP) before starting their treatment.

However, few studies have analyzed the long-term reproductive outcomes of these interventions, nor how patients ultimately use or do not use the FP options once in remission.

This project aims to better understand the effectiveness, utilization, and psychological impacts of these strategies.

This work is part of an effort to understand and evaluate fertility preservation practices implemented for women of reproductive age undergoing cancer treatment at the Amiens-Picardie University Hospital (CHU).

Its objective is to document patient pathways, clinical decisions, techniques employed, and reproductive outcomes observed after remission, in order to identify potential areas for improvement in the support and follow-up of these patients, thereby enhancing the overall quality and coordination of care.

This work is conducted alongside the development of a fertility observatory at the Department of Medicine and Reproductive Biology, CHU Amiens-Picardie.

Eligibility

Primary outcome measure(s)

• Occurrence of an identifiable reproductive outcome — 1 year
  Identifiable reproductive outcome are Spontaneous pregnancy, Use of preserved gametes or ovarian tissue (whether or not resulting in pregnancy), Use of donor oocytes, Discontinuation of the parenthood project

Trial sites (1)

More Centre Hospitalier Universitaire, Amiens trials in France

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