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Starting soon Not applicable

Correlation Study Between the Classification of Arthrogenic Motor Inhibition (AMI) and Clinical Assessment After ACL Rupture

NCT06945133 · tracked via the Priya Life Science France tracker
Phase
Not applicable
Started
2026-10-01
Last updated
2026-08-20

Condition(s) studied

ACL - Anterior Cruciate Ligament Rupture

Investigational drug(s) / intervention(s)

Clinical testing

Clinical testing: Intervention includes : * Surface EMG to measure inhibition of the VM and the rectus femoris (RF) on the injured and non-injured sides during attempts at voluntary contractions of the knee extensor muscles. * Myotonometry to measure the stiffness of the semimembranosus and biceps femoris (long head) on the injured and non-injured sides under resting conditions

Study summary

The goal of this interventional study is to measure medial vastus inhibition and associate it with AMI classification in patients with ACL rupture. The main question it aims to answer is:

Is there a correlation between AMI classification and clinical assessment after ACL rupture ? Participants will undergo surface EMG and Myotonometry.

Eligibility

Sex
ALL
Min age
18 Years
Max age
44 Years
Healthy volunteers
No
Inclusion Criteria: * Patient, male or female, aged ≥ 18 years and \< 45 years * Patient with an ACL rupture confirmed by MRI * Patient with an ACL rupture ≤ 30 days old * French speaking patient who does not object to the use of his/her data Exclusion Criteria: * Patient with previous ipsi or contralateral knee injury/surgery * Patient with multi-ligament injury * Pregnant or breastfeeding woman

Primary outcome measure(s)

  • Muscle Surface EMG and AMI correlation — From enrollment to Day 30
    Electrical signal amplitude, expressed in mV, is evaluated at the level of the VM. This electrical signal amplitude is correlated with the level of muscle activation. It is measured with a surface EMG, which measures the activation of the VM during a voluntary attempt to contract the knee extensors. The ratio: Amplitude of the electrical signal from the injured side of the VM / Amplitude of the electrical signal from the non-injured side of the VM is used to determine the inhibition of the VM. AMI is assessed using the Sonnery-Cottet classification (Sonnery-Cottet et al, 2022)

Trial sites (1)

FacilityCityRegionStatus
Hôpital Privé Jean Mermoz Lyon France
Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT06945133 on ClinicalTrials.gov ↗ ← All trials in France