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Clinical Trials in France / NCT02829190
Recruiting Phase 3

Feasibility Study of Phase-contrast MRI for Flow in the External Carotid Branches Arteries

NCT02829190 · tracked via the Priya Life Science France tracker
Sponsor
Centre Hospitalier Universitaire, Amiens
Phase
Phase 3
Started
2014-01-06
Last updated
2026-05-13

Condition(s) studied

Carotid Artery, External

Investigational drug(s) / intervention(s)

Magnetic Resonance Imaging (MRI),

Magnetic Resonance Imaging (MRI),: Magnetic Resonance Imaging (MRI) of flow using phase contrast (PC) methods

Study summary

The phase-contrast MRI offers the advantage to combine precisely vascular flow measurements data with morphological images.

Even if the anatomy of the external carotid artery is well known, data obtained through Phase contrast MRI could permit to progress in several fields of cranio-maxillofacial surgery as for example arteriovenous malformations,radionecrosis, head and neck micro-reconstructive surgery.

The aim of this study is to establish and develop Phase-contrast MRI sequences for vascular flow characterization branches of the external carotid artery in healthy patients and in pathological cases.

Eligibility

Sex
ALL
Min age
18 Years
Max age
70 Years
Healthy volunteers
Accepted
Inclusion Criteria: * group 1 : healthy volunteer * group 2 : X-Ray treatment antecedent (at least 50 grays and older than one year) * group 3 : antecedent of embolization of branches of external carotid artery * group 4 : antecedent of muscular free flap surgery (older than one month) * free and informed consent Exclusion Criteria: * group 1 : facial pathology, antecedent of facial injury, antecedent of X-Ray treatment in head and neck localisation, antecedent of head and neck cancer * group 2 : antecedent of surgery for head and neck cancer or for vascular disease * group 3 : antecedent of surgery for head and neck cancer or for vascular disease ; antecedent of X-Ray treatment. * group 4 : antecedent of surgery for head and neck cancer or for vascular disease ; antecedent of X-Ray treatment or embolization * patient with guardianship or trusteeship * MRI cons-indications * pregnancy and lactation

Primary outcome measure(s)

  • measurability of flow 1 — 1 hour
    flow data in the branches of external carotid artery in every 4 groups, characterized by measuring the maximum speed
  • measurability of flow 2 — 1 hour
    flow data in the branches of external carotid artery in every 4 groups, characterized by measuring the minimum speed
  • measurability of flow 3 — 1 hour
    flow data in the branches of external carotid artery in every 4 groups, characterized by measuring the average speed
  • measurability of flow 4 — 1 hour
    flow data in the branches of external carotid artery in every 4 groups, characterized by measuring the maximum flow rates
  • measurability of flow 5 — 1 hour
    flow data in the branches of external carotid artery in every 4 groups, characterized by measuring the minimal flow rates
  • measurability of flow 6 — 1 hour
    flow data in the branches of external carotid artery in every 4 groups, characterized by measuring the medium flow rates

Trial sites (1)

FacilityCityRegionStatus
Departement of Maxillo-Facial Surgery, Amiens University Hospital Amiens Picardie Recruiting

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Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT02829190 on ClinicalTrials.gov ↗ ← All trials in France